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Murcko scaffold

2-Azetidinone scaffold

485 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
485
With full pages
48
Scaffold SMILES

O=C1CCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 2-Azetidinone page
Murcko scaffold O=C1CCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 485 chemicals

tert-Butyl 2,2-dimethyl-4-oxoazetidine-1-carboxylate chemical structure, C10H17NO3, CAS 155300-46-2
tert-Butyl 2,2-dimethyl-4-oxoazetidine-1-carboxylate
CAS 155300-46-2C10H17NO3
2-Azetidinone, 4-ethyl-3-methyl-, trans- chemical structure, C6H11NO, CAS 5303-66-2
2-Azetidinone, 4-ethyl-3-methyl-, trans-
CAS 5303-66-2C6H11NO
3,3-Dimethyl-4-acetoxyazetidin-2-one chemical structure, C7H11NO3, CAS 28562-59-6
3,3-Dimethyl-4-acetoxyazetidin-2-one
CAS 28562-59-6C7H11NO3
2-Azetidinecarboxaldehyde, 1-(3-butynyl)-3-methoxy-4-oxo-, (2R,3R)- chemical structure, C9H11NO3, CAS 277757-71-8
2-Azetidinecarboxaldehyde, 1-(3-butynyl)-3-methoxy-4-oxo-, (2R,3R)-
CAS 277757-71-8C9H11NO3
(2S)-1-[tert-Butyl(dimethyl)silyl]-4-oxoazetidine-2-carboxylic acid chemical structure, C10H19NO3Si, CAS 82938-50-9
(2S)-1-[tert-Butyl(dimethyl)silyl]-4-oxoazetidine-2-carboxylic acid
CAS 82938-50-9C10H19NO3Si
2-Azetidinone, 4-ethenyl-, (S)- chemical structure, C5H7NO, CAS 28763-13-5
2-Azetidinone, 4-ethenyl-, (S)-
CAS 28763-13-5C5H7NO
2-Azetidinecarboxaldehyde, 3-methoxy-4-oxo-1-(2-propenyl)-, (2R,3R)- chemical structure, C8H11NO3, CAS 331258-83-4
2-Azetidinecarboxaldehyde, 3-methoxy-4-oxo-1-(2-propenyl)-, (2R,3R)-
CAS 331258-83-4C8H11NO3
[(2R,3S)-4-Oxo-3-propan-2-ylazetidin-2-yl] formate chemical structure, C7H11NO3, CAS 184424-12-2
[(2R,3S)-4-Oxo-3-propan-2-ylazetidin-2-yl] formate
CAS 184424-12-2C7H11NO3
2-Azetidinone, 1-methyl-4-(2-propenyl)- chemical structure, C7H11NO, CAS 216856-61-0
2-Azetidinone, 1-methyl-4-(2-propenyl)-
CAS 216856-61-0C7H11NO
2-Azetidinone, 4-(3-butenyl)- chemical structure, C7H11NO, CAS 74373-13-0
2-Azetidinone, 4-(3-butenyl)-
CAS 74373-13-0C7H11NO
3,3-Dimethyl-4-(propan-2-yl)azetidin-2-one chemical structure, C8H15NO, CAS 45735-37-3
3,3-Dimethyl-4-(propan-2-yl)azetidin-2-one
CAS 45735-37-3C8H15NO
Methyl (2S)-2-(hydroxymethyl)-4-oxoazetidine-2-carboxylate chemical structure, C6H9NO4, CAS 174283-17-1
Methyl (2S)-2-(hydroxymethyl)-4-oxoazetidine-2-carboxylate
CAS 174283-17-1C6H9NO4
(2S)-2-[(2S,3S)-3-[(1R)-1-[(tert-Butyldimethylsilyl)oxy]ethyl]-4-oxoazetidin-2-yl]propanoic acid chemical structure, C14H27NO4Si, CAS 97101-07-0
(2S)-2-[(2S,3S)-3-[(1R)-1-[(tert-Butyldimethylsilyl)oxy]ethyl]-4-oxoazetidin-2-yl]propanoic acid
CAS 97101-07-0C14H27NO4Si
4-Ethenyl-4-methylazetidin-2-one chemical structure, C6H9NO, CAS 20012-94-6
4-Ethenyl-4-methylazetidin-2-one
CAS 20012-94-6C6H9NO
Ethyl 4-oxoazetidine-2-carboxylate chemical structure, C6H9NO3, CAS 94271-43-9
Ethyl 4-oxoazetidine-2-carboxylate
CAS 94271-43-9C6H9NO3
4-(2-Oxopropyl)azetidin-2-one chemical structure, C6H9NO2, CAS 68485-90-5
4-(2-Oxopropyl)azetidin-2-one
CAS 68485-90-5C6H9NO2
4-(Vinyloxy)azetidin-2-one chemical structure, C5H7NO2, CAS 183319-83-7
4-(Vinyloxy)azetidin-2-one
CAS 183319-83-7C5H7NO2
[(2S,3S)-4-Oxo-3-propan-2-ylazetidin-2-yl] acetate chemical structure, C8H13NO3, CAS 127127-61-1
[(2S,3S)-4-Oxo-3-propan-2-ylazetidin-2-yl] acetate
CAS 127127-61-1C8H13NO3
Azetidon chemical structure, C13H25NO4Si, CAS 76855-69-1
Azetidon
CAS 76855-69-1C13H25NO4Si
1-Propanoylazetidin-2-one chemical structure, C6H9NO2, CAS 186819-35-2
1-Propanoylazetidin-2-one
CAS 186819-35-2C6H9NO2
2,2-Dimethyl-4-oxoazetidine-1-sulfonyl chloride chemical structure, C5H8ClNO3S, CAS 17174-96-8
2,2-Dimethyl-4-oxoazetidine-1-sulfonyl chloride
CAS 17174-96-8C5H8ClNO3S
(4S)-4-(Hydroxymethyl)azetidin-2-one chemical structure, C4H7NO2, CAS 72776-07-9
(4S)-4-(Hydroxymethyl)azetidin-2-one
CAS 72776-07-9C4H7NO2
Tebipenem pivoxil impurity 15 chemical structure, C13H25NO4Si, CAS 76899-07-5
Tebipenem pivoxil impurity 15
CAS 76899-07-5C13H25NO4Si
2-((2S,3S)-1-(tert-Butyldimethylsilyl)-3-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-4-oxoazetidin-2-yl)-2-methylmalonic acid chemical structure, C21H41NO6Si2, CAS 156630-85-2
2-((2S,3S)-1-(tert-Butyldimethylsilyl)-3-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-4-oxoazetidin-2-yl)-2-methylmalonic acid
CAS 156630-85-2C21H41NO6Si2