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Murcko scaffold

2-[5-(Phenoxymethyl)-1,2,4-oxadiazol-3-yl]pyridine scaffold

28 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
28
With full pages
6
Scaffold SMILES

c1ccc(OCc2nc(-c3ccccn3)no2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-[5-(Phenoxymethyl)-1,2,4-oxadiazol-3-yl]pyridine page
Murcko scaffold c1ccc(OCc2nc(-c3ccccn3)no2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

5-[(2-Methoxyphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C15H13N3O3, CAS 421581-86-4
5-[(2-Methoxyphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 421581-86-4C15H13N3O3
2-{5-[(4-Chloro-3,5-dimethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C16H14ClN3O2, CAS 352025-04-8
2-{5-[(4-Chloro-3,5-dimethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 352025-04-8C16H14ClN3O2
5-[(4-Chloro-2-methylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C15H12ClN3O2, CAS 568555-72-6
5-[(4-Chloro-2-methylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 568555-72-6C15H12ClN3O2
5-[(2,3-Dimethylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C16H15N3O2, CAS 690973-04-7
5-[(2,3-Dimethylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 690973-04-7C16H15N3O2
2-{5-[(4-Bromo-2-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H12BrN3O2, CAS 352343-82-9
2-{5-[(4-Bromo-2-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 352343-82-9C15H12BrN3O2
2-{5-[(4-Ethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C16H15N3O2, CAS 431921-96-9
2-{5-[(4-Ethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 431921-96-9C16H15N3O2
5-[(4-Propan-2-ylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C17H17N3O2, CAS 432510-75-3
5-[(4-Propan-2-ylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 432510-75-3C17H17N3O2
5-[(3,4-Dimethylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C16H15N3O2, CAS 432509-33-6
5-[(3,4-Dimethylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 432509-33-6C16H15N3O2
2-{5-[(4-Chloro-3-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H12ClN3O2, CAS 421584-07-8
2-{5-[(4-Chloro-3-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 421584-07-8C15H12ClN3O2
2-{5-[(2-Methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H13N3O2, CAS 352343-79-4
2-{5-[(2-Methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 352343-79-4C15H13N3O2
2-{5-[(4-Methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H13N3O2, CAS 442649-25-4
2-{5-[(4-Methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 442649-25-4C15H13N3O2
5-[(4-Bromophenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C14H10BrN3O2, CAS 381696-78-2
5-[(4-Bromophenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 381696-78-2C14H10BrN3O2
2-{5-[(4-Bromo-3-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H12BrN3O2, CAS 383371-23-1
2-{5-[(4-Bromo-3-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 383371-23-1C15H12BrN3O2
2-{5-[(2,5-Dimethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C16H15N3O2, CAS 431908-21-3
2-{5-[(2,5-Dimethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 431908-21-3C16H15N3O2
2-{5-[(3,5-Dimethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C16H15N3O2, CAS 378771-32-5
2-{5-[(3,5-Dimethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 378771-32-5C16H15N3O2
5-[(3-Methylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C15H13N3O2, CAS 421581-80-8
5-[(3-Methylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 421581-80-8C15H13N3O2
2-[5-(Phenoxymethyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C14H11N3O2, CAS 442651-09-4
2-[5-(Phenoxymethyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 442651-09-4C14H11N3O2
2-{5-[(4-tert-Butylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C18H19N3O2, CAS 420824-21-1
2-{5-[(4-tert-Butylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 420824-21-1C18H19N3O2
5-[(2-Bromo-4-chlorophenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C14H9BrClN3O2, CAS 378770-10-6
5-[(2-Bromo-4-chlorophenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 378770-10-6C14H9BrClN3O2
2-{5-[(2,4,5-Trichlorophenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C14H8Cl3N3O2, CAS 701253-73-8
2-{5-[(2,4,5-Trichlorophenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 701253-73-8C14H8Cl3N3O2
5-[(2-Bromo-4-methylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C15H12BrN3O2, CAS 421581-81-9
5-[(2-Bromo-4-methylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 421581-81-9C15H12BrN3O2
2-[5-[(3-Methoxyphenoxy)methyl]-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C15H13N3O3, CAS 351898-84-5
2-[5-[(3-Methoxyphenoxy)methyl]-1,2,4-oxadiazol-3-yl]pyridine
CAS 351898-84-5C15H13N3O3
2-{5-[1-(2,4-Dichlorophenoxy)ethyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H11Cl2N3O2, CAS 421575-58-8
2-{5-[1-(2,4-Dichlorophenoxy)ethyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 421575-58-8C15H11Cl2N3O2
5-[(2-Bromo-4-ethylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C16H14BrN3O2, CAS 587006-83-5
5-[(2-Bromo-4-ethylphenoxy)methyl]-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 587006-83-5C16H14BrN3O2