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Murcko scaffold

1,7-Naphthyridine scaffold

293 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
293
With full pages
32
Scaffold SMILES

c1cnc2cnccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,7-Naphthyridine page
Murcko scaffold c1cnc2cnccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 240 of 293 chemicals

8-Amino-1,7-naphthyridine-5-carboxamide chemical structure, C9H8N4O, CAS 2092801-61-9
8-Amino-1,7-naphthyridine-5-carboxamide
CAS 2092801-61-9C9H8N4O
3,5-Diiodo-1,7-naphthyridine chemical structure, C8H4I2N2, CAS 2733876-50-9
3,5-Diiodo-1,7-naphthyridine
CAS 2733876-50-9C8H4I2N2
4-Chloro-2,8-dimethyl-1,7-naphthyridine chemical structure, C10H9ClN2, CAS 2205097-55-6
4-Chloro-2,8-dimethyl-1,7-naphthyridine
CAS 2205097-55-6C10H9ClN2
2-Chloro-6-fluoro-1,7-naphthyridine chemical structure, C8H4ClFN2, CAS 2089054-23-7
2-Chloro-6-fluoro-1,7-naphthyridine
CAS 2089054-23-7C8H4ClFN2
5-Bromo-8-chloro-3-fluoro-1,7-naphthyridine chemical structure, C8H3BrClFN2, CAS 2167672-12-8
5-Bromo-8-chloro-3-fluoro-1,7-naphthyridine
CAS 2167672-12-8C8H3BrClFN2
8-Chloro-3,5-difluoro-1,7-naphthyridine chemical structure, C8H3ClF2N2, CAS 2306276-07-1
8-Chloro-3,5-difluoro-1,7-naphthyridine
CAS 2306276-07-1C8H3ClF2N2
8-Chloro-5-iodo-1,7-naphthyridine chemical structure, C8H4ClIN2, CAS 2306278-22-6
8-Chloro-5-iodo-1,7-naphthyridine
CAS 2306278-22-6C8H4ClIN2
8-Chloro-5-fluoro-1,7-naphthyridine chemical structure, C8H4ClFN2, CAS 2306271-19-0
8-Chloro-5-fluoro-1,7-naphthyridine
CAS 2306271-19-0C8H4ClFN2
8-Chloro-2-(propan-2-yloxy)-1,7-naphthyridine-3-carbonitrile chemical structure, C12H10ClN3O, CAS 2306265-08-5
8-Chloro-2-(propan-2-yloxy)-1,7-naphthyridine-3-carbonitrile
CAS 2306265-08-5C12H10ClN3O
5-Hydroxy-1,7-naphthyridine-6-carboxylic acid chemical structure, C9H6N2O3, CAS 70730-35-7
5-Hydroxy-1,7-naphthyridine-6-carboxylic acid
CAS 70730-35-7C9H6N2O3
1,7-Naphthyridin-5-ol chemical structure, C8H6N2O, CAS 70730-36-8
1,7-Naphthyridin-5-ol
CAS 70730-36-8C8H6N2O
Ethyl 5-Hydroxy-3-iodo[1,7]naphthyridine-6-carboxylate chemical structure, C11H9IN2O3, CAS 1098588-14-7
Ethyl 5-Hydroxy-3-iodo[1,7]naphthyridine-6-carboxylate
CAS 1098588-14-7C11H9IN2O3
3-Hydroxy-1,7-naphthyridine chemical structure, C8H6N2O, CAS 67967-09-3
3-Hydroxy-1,7-naphthyridine
CAS 67967-09-3C8H6N2O
8-Chloro-1,7-naphthyridin-3-ol chemical structure, C8H5ClN2O, CAS 1620981-38-5
8-Chloro-1,7-naphthyridin-3-ol
CAS 1620981-38-5C8H5ClN2O
8-Chloro-5-fluoro-1,7-naphthyridin-3-ol chemical structure, C8H4ClFN2O, CAS 1600512-28-4
8-Chloro-5-fluoro-1,7-naphthyridin-3-ol
CAS 1600512-28-4C8H4ClFN2O
8-Bromo-5-fluoro-1,7-naphthyridin-3-ol chemical structure, C8H4BrFN2O, CAS 1600512-29-5
8-Bromo-5-fluoro-1,7-naphthyridin-3-ol
CAS 1600512-29-5C8H4BrFN2O
2-Chloro-1,7-naphthyridin-5-ol chemical structure, C8H5ClN2O, CAS 1416146-95-6
2-Chloro-1,7-naphthyridin-5-ol
CAS 1416146-95-6C8H5ClN2O
1,7-Naphthyridine-4-carbonitrile chemical structure, C9H5N3, CAS 1584652-43-6
1,7-Naphthyridine-4-carbonitrile
CAS 1584652-43-6C9H5N3
1,7-Naphthyridin-6-amine dihydrochloride chemical structure, C8H9Cl2N3, CAS 2059993-86-9
1,7-Naphthyridin-6-amine dihydrochloride
CAS 2059993-86-9C8H9Cl2N3
8-Chloro-1,7-naphthyridine-2-carboxylic acid chemical structure, C9H5ClN2O2, CAS 2248343-88-4
8-Chloro-1,7-naphthyridine-2-carboxylic acid
CAS 2248343-88-4C9H5ClN2O2
4-Chloro-1,7-naphthyridine-2-carboxylic acid chemical structure, C9H5ClN2O2, CAS 2260933-06-8
4-Chloro-1,7-naphthyridine-2-carboxylic acid
CAS 2260933-06-8C9H5ClN2O2
Methyl 8-amino-1,7-naphthyridine-3-carboxylate chemical structure, C10H9N3O2, CAS 2241130-57-2
Methyl 8-amino-1,7-naphthyridine-3-carboxylate
CAS 2241130-57-2C10H9N3O2
Methyl 6-chloro-1,7-naphthyridine-2-carboxylate chemical structure, C10H7ClN2O2, CAS 2305252-35-9
Methyl 6-chloro-1,7-naphthyridine-2-carboxylate
CAS 2305252-35-9C10H7ClN2O2
6-Bromo-3-methyl-1,7-naphthyridin-2-amine chemical structure, C9H8BrN3, CAS 2361634-06-0
6-Bromo-3-methyl-1,7-naphthyridin-2-amine
CAS 2361634-06-0C9H8BrN3