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Murcko scaffold

1,7-Naphthyridine scaffold

293 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
293
With full pages
32
Scaffold SMILES

c1cnc2cnccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,7-Naphthyridine page
Murcko scaffold c1cnc2cnccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 288 of 293 chemicals

3-(Bromomethyl)-8-chloro-1,7-naphthyridine chemical structure, C9H6BrClN2, CAS 2540618-61-7
3-(Bromomethyl)-8-chloro-1,7-naphthyridine
CAS 2540618-61-7C9H6BrClN2
tert-Butyl (8-chloro-1,7-naphthyridin-3-yl)carbamate chemical structure, C13H14ClN3O2, CAS 2708286-96-6
tert-Butyl (8-chloro-1,7-naphthyridin-3-yl)carbamate
CAS 2708286-96-6C13H14ClN3O2
2-Chloro-1,7-naphthyridin-4-amine chemical structure, C8H6ClN3, CAS 2167760-55-4
2-Chloro-1,7-naphthyridin-4-amine
CAS 2167760-55-4C8H6ClN3
4-Chloro-1,7-naphthyridin-2-amine chemical structure, C8H6ClN3, CAS 2168130-42-3
4-Chloro-1,7-naphthyridin-2-amine
CAS 2168130-42-3C8H6ClN3
Ethyl 4-chloro-3-methyl-1,7-naphthyridine-2-carboxylate chemical structure, C12H11ClN2O2, CAS 2633071-59-5
Ethyl 4-chloro-3-methyl-1,7-naphthyridine-2-carboxylate
CAS 2633071-59-5C12H11ClN2O2
1,7-Naphthyridine-6-carbonitrile, 4-chloro- chemical structure, C9H4ClN3, CAS 2636672-70-1
1,7-Naphthyridine-6-carbonitrile, 4-chloro-
CAS 2636672-70-1C9H4ClN3
2-Chloro-8-methoxy-1,7-naphthyridine chemical structure, C9H7ClN2O, CAS 2636048-66-1
2-Chloro-8-methoxy-1,7-naphthyridine
CAS 2636048-66-1C9H7ClN2O
2,4,6-Trichloro-1,7-naphthyridine chemical structure, C8H3Cl3N2, CAS 2641328-59-6
2,4,6-Trichloro-1,7-naphthyridine
CAS 2641328-59-6C8H3Cl3N2
2-Amino-3-bromo-1,7-naphthyridine-6-carboxylic acid chemical structure, C9H6BrN3O2, CAS 2691878-65-4
2-Amino-3-bromo-1,7-naphthyridine-6-carboxylic acid
CAS 2691878-65-4C9H6BrN3O2
Methyl 2-amino-3-chloro-1,7-naphthyridine-6-carboxylate chemical structure, C10H8ClN3O2, CAS 2691881-60-2
Methyl 2-amino-3-chloro-1,7-naphthyridine-6-carboxylate
CAS 2691881-60-2C10H8ClN3O2
Methyl 2-amino-3-bromo-1,7-naphthyridine-6-carboxylate chemical structure, C10H8BrN3O2, CAS 2691881-61-3
Methyl 2-amino-3-bromo-1,7-naphthyridine-6-carboxylate
CAS 2691881-61-3C10H8BrN3O2
2-Amino-3-chloro-1,7-naphthyridine-6-carboxylic acid chemical structure, C9H6ClN3O2, CAS 2691878-64-3
2-Amino-3-chloro-1,7-naphthyridine-6-carboxylic acid
CAS 2691878-64-3C9H6ClN3O2
2-Amino-3-methyl-1,7-naphthyridine-6-carboxylic acid chemical structure, C10H9N3O2, CAS 2691878-63-2
2-Amino-3-methyl-1,7-naphthyridine-6-carboxylic acid
CAS 2691878-63-2C10H9N3O2
8-Ethynyl-6-methyl-1,7-naphthyridine chemical structure, C11H8N2, CAS 2705536-49-6
8-Ethynyl-6-methyl-1,7-naphthyridine
CAS 2705536-49-6C11H8N2
3,8-Dibromo-1,7-naphthyridine chemical structure, C8H4Br2N2, CAS 2759952-06-0
3,8-Dibromo-1,7-naphthyridine
CAS 2759952-06-0C8H4Br2N2
8-(Dimethylamino)-1,7-naphthyridine-5-carboxylic acid chemical structure, C11H11N3O2, CAS 2740660-59-5
8-(Dimethylamino)-1,7-naphthyridine-5-carboxylic acid
CAS 2740660-59-5C11H11N3O2
3-Bromo-8-chloro-6-methyl-1,7-naphthyridine chemical structure, C9H6BrClN2, CAS 2692638-19-8
3-Bromo-8-chloro-6-methyl-1,7-naphthyridine
CAS 2692638-19-8C9H6BrClN2
6-Chloro-1,7-naphthyridine-5-carbonitrile chemical structure, C9H4ClN3, CAS 1256463-74-7
6-Chloro-1,7-naphthyridine-5-carbonitrile
CAS 1256463-74-7C9H4ClN3
8-Chloro-1,7-naphthyridine-6-carboxylic acid hydrochloride chemical structure, C9H6Cl2N2O2, CAS 2803861-53-0
8-Chloro-1,7-naphthyridine-6-carboxylic acid hydrochloride
CAS 2803861-53-0C9H6Cl2N2O2
(1,7-Naphthyridin-8-yl)methanamine hydrochloride chemical structure, C9H10ClN3, CAS 2413867-05-5
(1,7-Naphthyridin-8-yl)methanamine hydrochloride
CAS 2413867-05-5C9H10ClN3
8-{[(tert-Butoxy)carbonyl]amino}-1,7-naphthyridine-3-carboxylic acid chemical structure, C14H15N3O4, CAS 2580248-65-1
8-{[(tert-Butoxy)carbonyl]amino}-1,7-naphthyridine-3-carboxylic acid
CAS 2580248-65-1C14H15N3O4
tert-Butyl 8-amino-1,7-naphthyridine-3-carboxylate chemical structure, C13H15N3O2, CAS 2639413-93-5
tert-Butyl 8-amino-1,7-naphthyridine-3-carboxylate
CAS 2639413-93-5C13H15N3O2
8-Acetamido-1,7-naphthyridine-3-carboxylic acid chemical structure, C11H9N3O3, CAS 2680749-97-5
8-Acetamido-1,7-naphthyridine-3-carboxylic acid
CAS 2680749-97-5C11H9N3O3
8-(2,2,2-Trifluoroacetamido)-1,7-naphthyridine-3-carboxylic acid chemical structure, C11H6F3N3O3, CAS 2680717-04-6
8-(2,2,2-Trifluoroacetamido)-1,7-naphthyridine-3-carboxylic acid
CAS 2680717-04-6C11H6F3N3O3