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Murcko scaffold

3-[(Pyrrolidin-1-yl)sulphonyl]pyridine scaffold

68 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
68
With full pages
6
Scaffold SMILES

O=S(=O)(c1cccnc1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-[(Pyrrolidin-1-yl)sulphonyl]pyridine page
Murcko scaffold O=S(=O)(c1cccnc1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 68 of 68 chemicals

N-(1-((6-Chloropyridin-3-yl)sulfonyl)pyrrolidin-3-yl)acetamide chemical structure, C11H14ClN3O3S, CAS 1988861-26-2
N-(1-((6-Chloropyridin-3-yl)sulfonyl)pyrrolidin-3-yl)acetamide
CAS 1988861-26-2C11H14ClN3O3S
(2S)-1-[[6-(Trifluoromethyl)-3-pyridinyl]sulfonyl]pyrrolidine-2-carboxylic acid chemical structure, C11H11F3N2O4S, CAS 1938701-97-3
(2S)-1-[[6-(Trifluoromethyl)-3-pyridinyl]sulfonyl]pyrrolidine-2-carboxylic acid
CAS 1938701-97-3C11H11F3N2O4S
(2R)-1-[[6-(Trifluoromethyl)-3-pyridinyl]sulfonyl]pyrrolidine-2-carboxylic acid chemical structure, C11H11F3N2O4S, CAS 1938472-97-9
(2R)-1-[[6-(Trifluoromethyl)-3-pyridinyl]sulfonyl]pyrrolidine-2-carboxylic acid
CAS 1938472-97-9C11H11F3N2O4S
tert-Butyl (1-((5-bromopyridin-3-yl)sulfonyl)pyrrolidin-3-yl)carbamate chemical structure, C14H20BrN3O4S, CAS 1953094-12-6
tert-Butyl (1-((5-bromopyridin-3-yl)sulfonyl)pyrrolidin-3-yl)carbamate
CAS 1953094-12-6C14H20BrN3O4S
5-(1-Pyrrolidinylsulfonyl)pyridine-3-boronic Acid chemical structure, C9H13BN2O4S, CAS 1617514-68-7
5-(1-Pyrrolidinylsulfonyl)pyridine-3-boronic Acid
CAS 1617514-68-7C9H13BN2O4S
2,5-Dichloro-3-[(2,2-dimethylpyrrolidin-1-yl)sulfonyl]pyridine chemical structure, C11H14Cl2N2O2S, CAS 2094528-55-7
2,5-Dichloro-3-[(2,2-dimethylpyrrolidin-1-yl)sulfonyl]pyridine
CAS 2094528-55-7C11H14Cl2N2O2S
3-[(2,2-Dimethylpyrrolidin-1-yl)sulfonyl]-2,6-difluoropyridine chemical structure, C11H14F2N2O2S, CAS 2094526-51-7
3-[(2,2-Dimethylpyrrolidin-1-yl)sulfonyl]-2,6-difluoropyridine
CAS 2094526-51-7C11H14F2N2O2S
6-Chloro-3-[(2,2-dimethylpyrrolidin-1-yl)sulfonyl]-2-fluoropyridine chemical structure, C11H14ClFN2O2S, CAS 2094624-58-3
6-Chloro-3-[(2,2-dimethylpyrrolidin-1-yl)sulfonyl]-2-fluoropyridine
CAS 2094624-58-3C11H14ClFN2O2S
3-[(2,2-Dimethylpyrrolidin-1-yl)sulfonyl]-2-fluoropyridine chemical structure, C11H15FN2O2S, CAS 2000826-03-7
3-[(2,2-Dimethylpyrrolidin-1-yl)sulfonyl]-2-fluoropyridine
CAS 2000826-03-7C11H15FN2O2S
2-Chloro-5-[(2,2-dimethylpyrrolidin-1-yl)sulfonyl]-4-(trifluoromethyl)pyridine chemical structure, C12H14ClF3N2O2S, CAS 2094484-23-6
2-Chloro-5-[(2,2-dimethylpyrrolidin-1-yl)sulfonyl]-4-(trifluoromethyl)pyridine
CAS 2094484-23-6C12H14ClF3N2O2S
5-{[(2s,4s)-4-Fluoro-2-(hydroxymethyl)pyrrolidin-1-yl]sulfonyl}pyridine-2-carbonitrile chemical structure, C11H12FN3O3S, CAS 2223382-31-6
5-{[(2s,4s)-4-Fluoro-2-(hydroxymethyl)pyrrolidin-1-yl]sulfonyl}pyridine-2-carbonitrile
CAS 2223382-31-6C11H12FN3O3S
3-{[(2s,4s)-4-Fluoro-2-(hydroxymethyl)pyrrolidin-1-yl]sulfonyl}pyridine-2-carbonitrile chemical structure, C11H12FN3O3S, CAS 2223226-92-2
3-{[(2s,4s)-4-Fluoro-2-(hydroxymethyl)pyrrolidin-1-yl]sulfonyl}pyridine-2-carbonitrile
CAS 2223226-92-2C11H12FN3O3S
5-{[(3s,4s)-3-(Hydroxymethyl)-4-methylpyrrolidin-1-yl]sulfonyl}pyridine-2-carbonitrile chemical structure, C12H15N3O3S, CAS 2223445-89-2
5-{[(3s,4s)-3-(Hydroxymethyl)-4-methylpyrrolidin-1-yl]sulfonyl}pyridine-2-carbonitrile
CAS 2223445-89-2C12H15N3O3S
3-[2-(2,2-Dimethylpropyl)pyrrolidin-1-yl]sulfonylpyridine-2-carbonitrile chemical structure, C15H21N3O2S, CAS 2134314-46-6
3-[2-(2,2-Dimethylpropyl)pyrrolidin-1-yl]sulfonylpyridine-2-carbonitrile
CAS 2134314-46-6C15H21N3O2S
3-[3-(Ethoxymethyl)pyrrolidin-1-yl]sulfonylpyridine-2-carbonitrile chemical structure, C13H17N3O3S, CAS 2224368-64-1
3-[3-(Ethoxymethyl)pyrrolidin-1-yl]sulfonylpyridine-2-carbonitrile
CAS 2224368-64-1C13H17N3O3S
[(2S,4S)-1-(5-Chloro-6-fluoropyridin-3-yl)sulfonyl-4-methoxypyrrolidin-2-yl]methanol chemical structure, C11H14ClFN2O4S, CAS 2248506-93-4
[(2S,4S)-1-(5-Chloro-6-fluoropyridin-3-yl)sulfonyl-4-methoxypyrrolidin-2-yl]methanol
CAS 2248506-93-4C11H14ClFN2O4S
1-(Pyridin-3-ylsulfonyl)pyrrolidin-3-amine dihydrochloride chemical structure, C9H15Cl2N3O2S, CAS 2839128-63-9
1-(Pyridin-3-ylsulfonyl)pyrrolidin-3-amine dihydrochloride
CAS 2839128-63-9C9H15Cl2N3O2S
(3R)-1-(Pyridine-3-sulfonyl)pyrrolidin-3-amine dihydrochloride chemical structure, C9H15Cl2N3O2S, CAS 1824925-72-5
(3R)-1-(Pyridine-3-sulfonyl)pyrrolidin-3-amine dihydrochloride
CAS 1824925-72-5C9H15Cl2N3O2S
3-Bromo-5-((3,3-difluoropyrrolidin-1-yl)sulfonyl)pyridine chemical structure, C9H9BrF2N2O2S, CAS 1995706-05-2
3-Bromo-5-((3,3-difluoropyrrolidin-1-yl)sulfonyl)pyridine
CAS 1995706-05-2C9H9BrF2N2O2S
tert-Butyl N-[5-bromo-3-(pyrrolidine-1-sulfonyl)pyridin-2-yl]carbamate chemical structure, C14H20BrN3O4S, CAS 2680715-21-1
tert-Butyl N-[5-bromo-3-(pyrrolidine-1-sulfonyl)pyridin-2-yl]carbamate
CAS 2680715-21-1C14H20BrN3O4S