Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

2,5-Diphenyl-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one scaffold

45 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 22
Chemicals: 45
With full pages: 14

Scaffold SMILES

O=C1CC(c2ccccc2)Sc2nc(-c3ccccc3)nn21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2,5-Diphenyl-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one page

Murcko scaffold O=C1CC(c2ccccc2)Sc2nc(-c3ccccc3)nn21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 45 of 45 chemicals

5-(4-Chlorophenyl)-2-phenyl-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one chemical structure, C17H12ClN3OS, CAS 403830-67-1

5-(4-Chlorophenyl)-2-phenyl-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one

CAS 403830-67-1C₁₇H₁₂ClN₃OS

5-(4-Methoxyphenyl)-2-phenyl-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C18H15N3O2S, CAS 403830-66-0

5-(4-Methoxyphenyl)-2-phenyl-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 403830-66-0C₁₈H₁₅N₃O₂S

2-Phenyl-5-(3,4,5-trimethoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C20H19N3O4S, CAS 384849-36-9

2-Phenyl-5-(3,4,5-trimethoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 384849-36-9C₂₀H₁₉N₃O₄S

5-(3,4-Dimethoxyphenyl)-2-phenyl-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one chemical structure, C19H17N3O3S, CAS 384849-37-0

5-(3,4-Dimethoxyphenyl)-2-phenyl-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one

CAS 384849-37-0C₁₉H₁₇N₃O₃S

2,5-Diphenyl-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C17H13N3OS, CAS 326907-47-5

2,5-Diphenyl-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 326907-47-5C₁₇H₁₃N₃OS

2-(4-Nitrophenyl)-5-phenyl-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C17H12N4O3S, CAS 384849-41-6

2-(4-Nitrophenyl)-5-phenyl-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 384849-41-6C₁₇H₁₂N₄O₃S

5-(4-Chlorophenyl)-2-(4-methoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C18H14ClN3O2S, CAS 403830-64-8

5-(4-Chlorophenyl)-2-(4-methoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 403830-64-8C₁₈H₁₄ClN₃O₂S

5-(4-Methoxyphenyl)-2-(4-methylphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C19H17N3O2S, CAS 433243-06-2

5-(4-Methoxyphenyl)-2-(4-methylphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 433243-06-2C₁₉H₁₇N₃O₂S

5-(4-Ethoxy-3-methoxyphenyl)-2-(4-methylphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C21H21N3O3S, CAS 433248-12-5

5-(4-Ethoxy-3-methoxyphenyl)-2-(4-methylphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 433248-12-5C₂₁H₂₁N₃O₃S

2-(4-Methylphenyl)-5-(3-nitrophenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C18H14N4O3S, CAS 433241-02-2

2-(4-Methylphenyl)-5-(3-nitrophenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 433241-02-2C₁₈H₁₄N₄O₃S

2-(4-Fluorophenyl)-5-(3,4,5-trimethoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C20H18FN3O4S, CAS 433327-67-4

2-(4-Fluorophenyl)-5-(3,4,5-trimethoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 433327-67-4C₂₀H₁₈FN₃O₄S

2-(4-Fluorophenyl)-5-phenyl-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C17H12FN3OS, CAS 433328-69-9

2-(4-Fluorophenyl)-5-phenyl-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 433328-69-9C₁₇H₁₂FN₃OS

2-(4-Methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C21H21N3O5S, CAS 433697-98-4

2-(4-Methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 433697-98-4C₂₁H₂₁N₃O₅S

5-(4-Ethoxy-3-methoxyphenyl)-2-(4-fluorophenyl)-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one chemical structure, C20H18FN3O3S, CAS 442556-14-1

5-(4-Ethoxy-3-methoxyphenyl)-2-(4-fluorophenyl)-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one

CAS 442556-14-1C₂₀H₁₈FN₃O₃S

2-(4-Fluorophenyl)-5-(3-nitrophenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C17H11FN4O3S, CAS 433699-97-9

2-(4-Fluorophenyl)-5-(3-nitrophenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 433699-97-9C₁₇H₁₁FN₄O₃S

2-(4-Fluorophenyl)-5-(4-methoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C18H14FN3O2S, CAS 433701-11-2

2-(4-Fluorophenyl)-5-(4-methoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 433701-11-2C₁₈H₁₄FN₃O₂S

2-(3,4-Diethoxyphenyl)-5-phenyl-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one chemical structure, C21H21N3O3S, CAS 609792-73-6

2-(3,4-Diethoxyphenyl)-5-phenyl-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one

CAS 609792-73-6C₂₁H₂₁N₃O₃S

2-(3,4-Diethoxyphenyl)-5-(4-fluorophenyl)-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one chemical structure, C21H20FN3O3S, CAS 609792-41-8

2-(3,4-Diethoxyphenyl)-5-(4-fluorophenyl)-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one

CAS 609792-41-8C₂₁H₂₀FN₃O₃S

5-(3-Fluorophenyl)-2-(4-methoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C18H14FN3O2S, CAS 609792-28-1

5-(3-Fluorophenyl)-2-(4-methoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 609792-28-1C₁₈H₁₄FN₃O₂S

5-(4-Methoxyphenyl)-2-(m-tolyl)-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one chemical structure, C19H17N3O2S, CAS 620569-82-6

5-(4-Methoxyphenyl)-2-(m-tolyl)-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one

CAS 620569-82-6C₁₉H₁₇N₃O₂S

2-(4-Chlorophenyl)-5-(3,4-dimethoxyphenyl)-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one chemical structure, C19H16ClN3O3S, CAS 620570-79-8

2-(4-Chlorophenyl)-5-(3,4-dimethoxyphenyl)-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one

CAS 620570-79-8C₁₉H₁₆ClN₃O₃S

2-(4-Chlorophenyl)-5-(3-nitrophenyl)-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one chemical structure, C17H11ClN4O3S, CAS 637320-39-9

2-(4-Chlorophenyl)-5-(3-nitrophenyl)-5H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7(6H)-one

CAS 637320-39-9C₁₇H₁₁ClN₄O₃S

5-(3,4-Dichlorophenyl)-2-phenyl-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C17H11Cl2N3OS, CAS 637325-88-3

5-(3,4-Dichlorophenyl)-2-phenyl-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 637325-88-3C₁₇H₁₁Cl₂N₃OS

2-(3,4-Dichlorophenyl)-5-(3-fluorophenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one chemical structure, C17H10Cl2FN3OS, CAS 690246-58-3

2-(3,4-Dichlorophenyl)-5-(3-fluorophenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

CAS 690246-58-3C₁₇H₁₀Cl₂FN₃OS