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Murcko scaffold

2,5-Diphenylpyrazolo[1,5-a]pyrimidin-7-ol scaffold

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
14
With full pages
3
Scaffold SMILES

O=c1cc(-c2ccccc2)nc2cc(-c3ccccc3)[nH]n12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,5-Diphenylpyrazolo[1,5-a]pyrimidin-7-ol page
Murcko scaffold O=c1cc(-c2ccccc2)nc2cc(-c3ccccc3)[nH]n12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

2-(2-Chlorophenyl)-5-phenylpyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C18H12ClN3O, CAS 603098-19-7
2-(2-Chlorophenyl)-5-phenylpyrazolo[1,5-a]pyrimidin-7-ol
CAS 603098-19-7C18H12ClN3O
2-(4-Bromophenyl)-5-{4-nitrophenyl}pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C18H11BrN4O3, CAS 333769-73-6
2-(4-Bromophenyl)-5-{4-nitrophenyl}pyrazolo[1,5-a]pyrimidin-7-ol
CAS 333769-73-6C18H11BrN4O3
5-{4-Nitrophenyl}-2-(4-iodophenyl)pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C18H11IN4O3, CAS 423149-88-6
5-{4-Nitrophenyl}-2-(4-iodophenyl)pyrazolo[1,5-a]pyrimidin-7-ol
CAS 423149-88-6C18H11IN4O3
2-(3-Fluorophenyl)-5-{4-nitrophenyl}pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C18H11FN4O3, CAS 333325-46-5
2-(3-Fluorophenyl)-5-{4-nitrophenyl}pyrazolo[1,5-a]pyrimidin-7-ol
CAS 333325-46-5C18H11FN4O3
2-(3,4-Dimethoxyphenyl)-5-phenylpyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C20H17N3O3, CAS 606116-42-1
2-(3,4-Dimethoxyphenyl)-5-phenylpyrazolo[1,5-a]pyrimidin-7-ol
CAS 606116-42-1C20H17N3O3
2-(3,5-Dimethoxyphenyl)-5-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one chemical structure, C20H17N3O3, CAS 606116-50-1
2-(3,5-Dimethoxyphenyl)-5-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
CAS 606116-50-1C20H17N3O3
2,5-Diphenylpyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C18H13N3O, CAS 5790-45-4
2,5-Diphenylpyrazolo[1,5-a]pyrimidin-7-ol
CAS 5790-45-4C18H13N3O
2-(3-Methoxyphenyl)-5-phenylpyrazolo[1,5-A]pyrimidin-7-ol chemical structure, C19H15N3O2, CAS 606116-33-0
2-(3-Methoxyphenyl)-5-phenylpyrazolo[1,5-A]pyrimidin-7-ol
CAS 606116-33-0C19H15N3O2
5-[3,5-Bis(Trifluoromethyl)phenyl]-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C20H11F6N3O, CAS 882285-70-3
5-[3,5-Bis(Trifluoromethyl)phenyl]-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
CAS 882285-70-3C20H11F6N3O
5-Phenyl-2-m-tolyl-pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C19H15N3O, CAS 331422-45-8
5-Phenyl-2-m-tolyl-pyrazolo[1,5-a]pyrimidin-7-ol
CAS 331422-45-8C19H15N3O
2-(3-Fluorophenyl)-5-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one chemical structure, C18H12FN3O, CAS 6137-13-9
2-(3-Fluorophenyl)-5-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
CAS 6137-13-9C18H12FN3O
2-(3,4-Dimethoxyphenyl)-5-(4-nitrophenyl)pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C20H16N4O5, CAS 606114-57-2
2-(3,4-Dimethoxyphenyl)-5-(4-nitrophenyl)pyrazolo[1,5-a]pyrimidin-7-ol
CAS 606114-57-2C20H16N4O5
2-(4-Methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C22H21N3O5, CAS 606114-56-1
2-(4-Methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-ol
CAS 606114-56-1C22H21N3O5
5-[3,5-Bis(Trifluoromethyl)phenyl]-2-(4-nitrophenyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C20H10F6N4O3, CAS 2246950-48-9
5-[3,5-Bis(Trifluoromethyl)phenyl]-2-(4-nitrophenyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
CAS 2246950-48-9C20H10F6N4O3