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Murcko scaffold

N-(1,3-Dioxoisoindolin-5-yl)-2-(phenylthio)acetamide scaffold

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
10
With full pages
5
Scaffold SMILES

O=C(CSc1ccccc1)Nc1ccc2c(c1)C(=O)NC2=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(1,3-Dioxoisoindolin-5-yl)-2-(phenylthio)acetamide page
Murcko scaffold O=C(CSc1ccccc1)Nc1ccc2c(c1)C(=O)NC2=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-(4-Chlorophenyl)sulfanyl-N-(1,3-dioxoisoindol-5-yl)acetamide chemical structure, C16H11ClN2O3S, CAS 500264-57-3
2-(4-Chlorophenyl)sulfanyl-N-(1,3-dioxoisoindol-5-yl)acetamide
CAS 500264-57-3C16H11ClN2O3S
N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-2-[(4-methylphenyl)sulfanyl]acetamide chemical structure, C17H14N2O3S, CAS 701272-49-3
N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-2-[(4-methylphenyl)sulfanyl]acetamide
CAS 701272-49-3C17H14N2O3S
3-(1,3-Dioxo-5-{[(phenylthio)acetyl]amino}-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C19H16N2O5S, CAS 823834-20-4
3-(1,3-Dioxo-5-{[(phenylthio)acetyl]amino}-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CAS 823834-20-4C19H16N2O5S
3-[5-({[(4-Chlorophenyl)sulfanyl]acetyl}amino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]propanoic acid chemical structure, C19H15ClN2O5S, CAS 831242-83-2
3-[5-({[(4-Chlorophenyl)sulfanyl]acetyl}amino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]propanoic acid
CAS 831242-83-2C19H15ClN2O5S
N-(1,3-Dioxoisoindolin-5-yl)-2-(phenylthio)acetamide chemical structure, C16H12N2O3S, CAS 518008-30-5
N-(1,3-Dioxoisoindolin-5-yl)-2-(phenylthio)acetamide
CAS 518008-30-5C16H12N2O3S
N-(2-Methyl-1,3-dioxoisoindol-5-yl)-2-(4-methylphenyl)sulfanylacetamide chemical structure, C18H16N2O3S, CAS 895455-86-4
N-(2-Methyl-1,3-dioxoisoindol-5-yl)-2-(4-methylphenyl)sulfanylacetamide
CAS 895455-86-4C18H16N2O3S
N-(2-Methyl-1,3-dioxoisoindol-5-yl)-2-phenylsulfanylacetamide chemical structure, C17H14N2O3S, CAS 895484-05-6
N-(2-Methyl-1,3-dioxoisoindol-5-yl)-2-phenylsulfanylacetamide
CAS 895484-05-6C17H14N2O3S
2-(4-Fluorophenyl)sulfanyl-N-(2-methyl-1,3-dioxoisoindol-5-yl)acetamide chemical structure, C17H13FN2O3S, CAS 896344-29-9
2-(4-Fluorophenyl)sulfanyl-N-(2-methyl-1,3-dioxoisoindol-5-yl)acetamide
CAS 896344-29-9C17H13FN2O3S
N-(1,3-Dioxoisoindolin-5-yl)-2-((4-methoxyphenyl)thio)acetamide chemical structure, C17H14N2O4S, CAS 851200-34-5
N-(1,3-Dioxoisoindolin-5-yl)-2-((4-methoxyphenyl)thio)acetamide
CAS 851200-34-5C17H14N2O4S
2-((4-Methoxyphenyl)thio)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)acetamide chemical structure, C18H16N2O4S, CAS 923103-09-7
2-((4-Methoxyphenyl)thio)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)acetamide
CAS 923103-09-7C18H16N2O4S