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Murcko scaffold

Ring system with 3 rings and 22 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
15
With full pages
5
Scaffold SMILES

O=C(COc1ccc2ccc(=O)oc2c1)NC1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccc2ccc(=O)oc2c1)NC1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

N-Cyclohexyl-2-(4-methyl-2-oxochromen-7-yl)oxyacetamide chemical structure, C18H21NO4, CAS 300814-09-9
N-Cyclohexyl-2-(4-methyl-2-oxochromen-7-yl)oxyacetamide
CAS 300814-09-9C18H21NO4
N-Cyclohexyl-2-[(6-ethyl-4-methyl-2-oxo-2H-chromen-7-yl)oxy]acetamide chemical structure, C20H25NO4, CAS 749214-31-1
N-Cyclohexyl-2-[(6-ethyl-4-methyl-2-oxo-2H-chromen-7-yl)oxy]acetamide
CAS 749214-31-1C20H25NO4
2-(6-Chloro-4-methyl-2-oxochromen-7-yl)oxy-N-cyclohexylacetamide chemical structure, C18H20ClNO4, CAS 853723-26-9
2-(6-Chloro-4-methyl-2-oxochromen-7-yl)oxy-N-cyclohexylacetamide
CAS 853723-26-9C18H20ClNO4
2-[(6-Chloro-4-methyl-2-oxo-2H-chromen-7-yl)oxy]-N-(1-cyanocyclohexyl)acetamide chemical structure, C19H19ClN2O4, CAS 849181-07-3
2-[(6-Chloro-4-methyl-2-oxo-2H-chromen-7-yl)oxy]-N-(1-cyanocyclohexyl)acetamide
CAS 849181-07-3C19H19ClN2O4
2-[(6-Chloro-2-oxo-4-propyl-2H-chromen-7-yl)oxy]-N-(2,3-dimethylcyclohexyl)acetamide chemical structure, C22H28ClNO4, CAS 1005085-04-0
2-[(6-Chloro-2-oxo-4-propyl-2H-chromen-7-yl)oxy]-N-(2,3-dimethylcyclohexyl)acetamide
CAS 1005085-04-0C22H28ClNO4
N-(1-Cyanocyclohexyl)-2-[(2-oxo-2H-chromen-7-yl)oxy]acetamide chemical structure, C18H18N2O4, CAS 926585-96-8
N-(1-Cyanocyclohexyl)-2-[(2-oxo-2H-chromen-7-yl)oxy]acetamide
CAS 926585-96-8C18H18N2O4
N-(1-Cyanocyclohexyl)-2-(4-methyl-2-oxochromen-7-yl)oxyacetamide chemical structure, C19H20N2O4, CAS 1090339-75-5
N-(1-Cyanocyclohexyl)-2-(4-methyl-2-oxochromen-7-yl)oxyacetamide
CAS 1090339-75-5C19H20N2O4
N-(1-Cyanocyclohexyl)-N-methyl-2-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]propanamide chemical structure, C21H24N2O4, CAS 930075-70-0
N-(1-Cyanocyclohexyl)-N-methyl-2-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]propanamide
CAS 930075-70-0C21H24N2O4
N-(1-Cyanocyclohexyl)-2-(4-methyl-2-oxochromen-7-yl)oxypropanamide chemical structure, C20H22N2O4, CAS 875471-95-7
N-(1-Cyanocyclohexyl)-2-(4-methyl-2-oxochromen-7-yl)oxypropanamide
CAS 875471-95-7C20H22N2O4
N-(1-Cyanocyclohexyl)-2-[(2-oxo-2H-chromen-7-yl)oxy]propanamide chemical structure, C19H20N2O4, CAS 875630-66-3
N-(1-Cyanocyclohexyl)-2-[(2-oxo-2H-chromen-7-yl)oxy]propanamide
CAS 875630-66-3C19H20N2O4
N-(1-Cyanocyclohexyl)-2-{[2-oxo-4-(propan-2-yl)-2H-chromen-7-yl]oxy}acetamide chemical structure, C21H24N2O4, CAS 930891-78-4
N-(1-Cyanocyclohexyl)-2-{[2-oxo-4-(propan-2-yl)-2H-chromen-7-yl]oxy}acetamide
CAS 930891-78-4C21H24N2O4
2-[(6-Chloro-4-methyl-2-oxo-2H-chromen-7-yl)oxy]-N-(1-cyanocyclohexyl)-N-methylacetamide chemical structure, C20H21ClN2O4, CAS 940235-70-1
2-[(6-Chloro-4-methyl-2-oxo-2H-chromen-7-yl)oxy]-N-(1-cyanocyclohexyl)-N-methylacetamide
CAS 940235-70-1C20H21ClN2O4
N-(1-Cyanocyclohexyl)-N-methyl-2-[(2-oxo-2H-chromen-7-yl)oxy]acetamide chemical structure, C19H20N2O4, CAS 940816-55-7
N-(1-Cyanocyclohexyl)-N-methyl-2-[(2-oxo-2H-chromen-7-yl)oxy]acetamide
CAS 940816-55-7C19H20N2O4
N-(1-Cyanocyclohexyl)-2-(4,8-dimethyl-2-oxochromen-7-yl)oxy-N-methylacetamide chemical structure, C21H24N2O4, CAS 940816-57-9
N-(1-Cyanocyclohexyl)-2-(4,8-dimethyl-2-oxochromen-7-yl)oxy-N-methylacetamide
CAS 940816-57-9C21H24N2O4
N-(1-Cyanocyclohexyl)-N-methyl-2-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]acetamide chemical structure, C20H22N2O4, CAS 926780-53-2
N-(1-Cyanocyclohexyl)-N-methyl-2-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]acetamide
CAS 926780-53-2C20H22N2O4