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Murcko scaffold

Ring system with 3 rings and 18 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
14
With full pages
3
Scaffold SMILES

c1ccc(-c2ccnc(N3CCOCC3)c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccnc(N3CCOCC3)c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

2-Morpholino-4-phenylnicotinonitrile chemical structure, C16H15N3O, CAS 339103-55-8
2-Morpholino-4-phenylnicotinonitrile
CAS 339103-55-8C16H15N3O
4-(4-Chlorophenyl)-2-(4-morpholinyl)-3-pyridinecarbonitrile chemical structure, C16H14ClN3O, CAS 478080-41-0
4-(4-Chlorophenyl)-2-(4-morpholinyl)-3-pyridinecarbonitrile
CAS 478080-41-0C16H14ClN3O
4-(4-Fluorophenyl)-2-morpholinonicotinonitrile chemical structure, C16H14FN3O, CAS 478245-84-0
4-(4-Fluorophenyl)-2-morpholinonicotinonitrile
CAS 478245-84-0C16H14FN3O
6-Morpholin-4-yl-4-o-tolyl-nicotinamide chemical structure, C17H19N3O2, CAS 342417-06-5
6-Morpholin-4-yl-4-o-tolyl-nicotinamide
CAS 342417-06-5C17H19N3O2
3-Pyridinecarbonitrile, 4-(2-methylphenyl)-6-(4-morpholinyl)- chemical structure, C17H17N3O, CAS 825638-01-5
3-Pyridinecarbonitrile, 4-(2-methylphenyl)-6-(4-morpholinyl)-
CAS 825638-01-5C17H17N3O
3-Pyridinecarbonitrile, 2-chloro-4-(2-methylphenyl)-6-(4-morpholinyl)- chemical structure, C17H16ClN3O, CAS 873443-68-6
3-Pyridinecarbonitrile, 2-chloro-4-(2-methylphenyl)-6-(4-morpholinyl)-
CAS 873443-68-6C17H16ClN3O
N-tert-Butyl-6-morpholin-4-YL-4-O-tolyl-nicotinamide chemical structure, C21H27N3O2, CAS 342417-05-4
N-tert-Butyl-6-morpholin-4-YL-4-O-tolyl-nicotinamide
CAS 342417-05-4C21H27N3O2
(6-Morpholin-4-yl-4-o-tolyl-pyridin-3-yl)-carbamic acid methyl ester chemical structure, C18H21N3O3, CAS 342417-07-6
(6-Morpholin-4-yl-4-o-tolyl-pyridin-3-yl)-carbamic acid methyl ester
CAS 342417-07-6C18H21N3O3
6-Morpholin-4-yl-4-o-tolyl-pyridin-3-ylamine chemical structure, C16H19N3O, CAS 290297-35-7
6-Morpholin-4-yl-4-o-tolyl-pyridin-3-ylamine
CAS 290297-35-7C16H19N3O
2-Chloro-4-(2-methylphenyl)-6-(4-morpholinyl)nicotinamide chemical structure, C17H18ClN3O2, CAS 873443-63-1
2-Chloro-4-(2-methylphenyl)-6-(4-morpholinyl)nicotinamide
CAS 873443-63-1C17H18ClN3O2
3-[3-(2-Morpholin-4-yl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester chemical structure, C22H26N2O4, CAS 579476-69-0
3-[3-(2-Morpholin-4-yl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester
CAS 579476-69-0C22H26N2O4
3-(2-Chloro-6-morpholinopyridin-4-yl)-4-methylaniline chemical structure, C16H18ClN3O, CAS 1628840-11-8
3-(2-Chloro-6-morpholinopyridin-4-yl)-4-methylaniline
CAS 1628840-11-8C16H18ClN3O
3-(2-Chloro-3-fluoro-6-morpholinopyridin-4-yl)-4-methylaniline chemical structure, C16H17ClFN3O, CAS 1800400-02-5
3-(2-Chloro-3-fluoro-6-morpholinopyridin-4-yl)-4-methylaniline
CAS 1800400-02-5C16H17ClFN3O
3-(2-Fluoro-6-morpholinopyridin-4-yl)-4-methylaniline chemical structure, C16H18FN3O, CAS 1800401-62-0
3-(2-Fluoro-6-morpholinopyridin-4-yl)-4-methylaniline
CAS 1800401-62-0C16H18FN3O