CompoundList
Sign in
Murcko scaffold

1-Benzyl-6-hydroxy-2-oxo-N-phenyl-1,2-dihydro-4-pyrimidinecarboxamide scaffold

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
21
With full pages
3
Scaffold SMILES

O=C(Nc1ccccc1)c1cc(=O)n(Cc2ccccc2)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzyl-6-hydroxy-2-oxo-N-phenyl-1,2-dihydro-4-pyrimidinecarboxamide page
Murcko scaffold O=C(Nc1ccccc1)c1cc(=O)n(Cc2ccccc2)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

1-Benzyl-N-(2,6-dichlorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C18H13Cl2N3O3, CAS 338412-53-6
1-Benzyl-N-(2,6-dichlorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-53-6C18H13Cl2N3O3
1-Benzyl-N-(4-chlorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C18H14ClN3O3, CAS 338412-47-8
1-Benzyl-N-(4-chlorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-47-8C18H14ClN3O3
1-Benzyl-N-(3-chloro-2-methylphenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C19H16ClN3O3, CAS 338412-67-2
1-Benzyl-N-(3-chloro-2-methylphenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-67-2C19H16ClN3O3
1-Benzyl-N-(2-fluorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C18H14FN3O3, CAS 338412-73-0
1-Benzyl-N-(2-fluorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-73-0C18H14FN3O3
1-Benzyl-N-(3,5-dichlorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C18H13Cl2N3O3, CAS 338412-50-3
1-Benzyl-N-(3,5-dichlorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-50-3C18H13Cl2N3O3
1-Benzyl-N-(3,4-dichlorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C18H13Cl2N3O3, CAS 338412-54-7
1-Benzyl-N-(3,4-dichlorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-54-7C18H13Cl2N3O3
1-Benzyl-N-(2,4-difluorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C18H13F2N3O3, CAS 338412-75-2
1-Benzyl-N-(2,4-difluorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-75-2C18H13F2N3O3
1-Benzyl-N-(3-chloro-2,4-difluorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C18H12ClF2N3O3, CAS 861212-11-5
1-Benzyl-N-(3-chloro-2,4-difluorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 861212-11-5C18H12ClF2N3O3
1-Benzyl-6-hydroxy-N-(4-methoxyphenyl)-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C19H17N3O4, CAS 861212-17-1
1-Benzyl-6-hydroxy-N-(4-methoxyphenyl)-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 861212-17-1C19H17N3O4
1-Benzyl-6-hydroxy-2-oxo-N-[3-(trifluoromethyl)phenyl]-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C19H14F3N3O3, CAS 338412-63-8
1-Benzyl-6-hydroxy-2-oxo-N-[3-(trifluoromethyl)phenyl]-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-63-8C19H14F3N3O3
1-Benzyl-N-(3,4-dimethylphenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C20H19N3O3, CAS 338412-52-5
1-Benzyl-N-(3,4-dimethylphenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-52-5C20H19N3O3
1-Benzyl-N-(4-bromophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C18H14BrN3O3, CAS 338412-51-4
1-Benzyl-N-(4-bromophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-51-4C18H14BrN3O3
1-Benzyl-6-hydroxy-2-oxo-N-[4-(trifluoromethoxy)phenyl]-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C19H14F3N3O4, CAS 338412-65-0
1-Benzyl-6-hydroxy-2-oxo-N-[4-(trifluoromethoxy)phenyl]-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-65-0C19H14F3N3O4
1-Benzyl-6-hydroxy-N-(3-methoxyphenyl)-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C19H17N3O4, CAS 338412-64-9
1-Benzyl-6-hydroxy-N-(3-methoxyphenyl)-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-64-9C19H17N3O4
1-Benzyl-6-hydroxy-N-(3-methylphenyl)-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C19H17N3O3, CAS 861212-10-4
1-Benzyl-6-hydroxy-N-(3-methylphenyl)-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 861212-10-4C19H17N3O3
1-Benzyl-6-hydroxy-2-oxo-N-phenyl-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C18H15N3O3, CAS 338412-66-1
1-Benzyl-6-hydroxy-2-oxo-N-phenyl-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-66-1C18H15N3O3
1-Benzyl-N-(2,4-dichlorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C18H13Cl2N3O3, CAS 338412-48-9
1-Benzyl-N-(2,4-dichlorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-48-9C18H13Cl2N3O3
1-Benzyl-N-(2,3-dichlorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C18H13Cl2N3O3, CAS 338412-49-0
1-Benzyl-N-(2,3-dichlorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-49-0C18H13Cl2N3O3
1-Benzyl-6-hydroxy-2-oxo-N-[4-(trifluoromethyl)phenyl]-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C19H14F3N3O3, CAS 338412-62-7
1-Benzyl-6-hydroxy-2-oxo-N-[4-(trifluoromethyl)phenyl]-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-62-7C19H14F3N3O3
1-Benzyl-N-(4-fluorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C18H14FN3O3, CAS 338412-74-1
1-Benzyl-N-(4-fluorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-74-1C18H14FN3O3
1-Benzyl-N-(3,4-difluorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide chemical structure, C18H13F2N3O3, CAS 338412-76-3
1-Benzyl-N-(3,4-difluorophenyl)-6-hydroxy-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide
CAS 338412-76-3C18H13F2N3O3