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Murcko scaffold

Ring system with 3 rings and 18 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
13
With full pages
5
Scaffold SMILES

c1ccc(-c2ccnc(N3CCOCC3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccnc(N3CCOCC3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

2-Morpholin-4-yl-6-phenylpyrimidine-4-carboxamide chemical structure, C15H16N4O2, CAS 378766-17-7
2-Morpholin-4-yl-6-phenylpyrimidine-4-carboxamide
CAS 378766-17-7C15H16N4O2
4-(4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)morpholine chemical structure, C15H14F3N3O, CAS 615273-95-5
4-(4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)morpholine
CAS 615273-95-5C15H14F3N3O
4-[4-(4-Chlorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl]morpholine chemical structure, C15H13ClF3N3O, CAS 380876-91-5
4-[4-(4-Chlorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl]morpholine
CAS 380876-91-5C15H13ClF3N3O
4-[4-(3-Methoxyphenyl)-6-(trifluoromethyl)-2-pyrimidinyl]morpholine chemical structure, C16H16F3N3O2, CAS 686725-29-1
4-[4-(3-Methoxyphenyl)-6-(trifluoromethyl)-2-pyrimidinyl]morpholine
CAS 686725-29-1C16H16F3N3O2
4-[4-(2-Methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]morpholine chemical structure, C16H16F3N3O2, CAS 725695-33-0
4-[4-(2-Methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]morpholine
CAS 725695-33-0C16H16F3N3O2
4-(4-(3,4-Dimethoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl)morpholine chemical structure, C17H18F3N3O3, CAS 686725-39-3
4-(4-(3,4-Dimethoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl)morpholine
CAS 686725-39-3C17H18F3N3O3
4-(4-Methoxyphenyl)-2-morpholin-4-ylpyrimidine-5-carboxylic acid chemical structure, C16H17N3O4, CAS 1340872-36-7
4-(4-Methoxyphenyl)-2-morpholin-4-ylpyrimidine-5-carboxylic acid
CAS 1340872-36-7C16H17N3O4
4-(3-Methylphenyl)-2-morpholin-4-ylpyrimidine-5-carboxylic acid chemical structure, C16H17N3O3, CAS 1340705-83-0
4-(3-Methylphenyl)-2-morpholin-4-ylpyrimidine-5-carboxylic acid
CAS 1340705-83-0C16H17N3O3
4-(4-Chlorophenyl)-2-(morpholin-4-yl)pyrimidine-5-carboxylic acid chemical structure, C15H14ClN3O3, CAS 1775474-37-7
4-(4-Chlorophenyl)-2-(morpholin-4-yl)pyrimidine-5-carboxylic acid
CAS 1775474-37-7C15H14ClN3O3
4-(3-Methoxyphenyl)-2-morpholino-5-pyrimidinecarboxylic acid chemical structure, C16H17N3O4, CAS 1775400-37-7
4-(3-Methoxyphenyl)-2-morpholino-5-pyrimidinecarboxylic acid
CAS 1775400-37-7C16H17N3O4
4-(4-Methylphenyl)-2-morpholino-5-pyrimidinecarboxylic acid chemical structure, C16H17N3O3, CAS 1775368-12-1
4-(4-Methylphenyl)-2-morpholino-5-pyrimidinecarboxylic acid
CAS 1775368-12-1C16H17N3O3
4-(3,5-Difluorophenyl)-2-(morpholin-4-yl)pyrimidine-5-carboxylic acid chemical structure, C15H13F2N3O3, CAS 1775345-59-9
4-(3,5-Difluorophenyl)-2-(morpholin-4-yl)pyrimidine-5-carboxylic acid
CAS 1775345-59-9C15H13F2N3O3
4-(3-Chlorophenyl)-2-(morpholin-4-yl)pyrimidine-5-carboxylic acid chemical structure, C15H14ClN3O3, CAS 1798680-79-1
4-(3-Chlorophenyl)-2-(morpholin-4-yl)pyrimidine-5-carboxylic acid
CAS 1798680-79-1C15H14ClN3O3