CompoundList
Sign in
Murcko scaffold

4-Phenyl-1,2,3,4-tetrahydro-isoquinoline scaffold

112 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
112
With full pages
18
Scaffold SMILES

c1ccc(C2CNCc3ccccc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenyl-1,2,3,4-tetrahydro-isoquinoline page
Murcko scaffold c1ccc(C2CNCc3ccccc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 112 chemicals

4-(3-Methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride chemical structure, C16H18ClNO, CAS 108772-71-0
4-(3-Methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride
CAS 108772-71-0C16H18ClNO
4-(3-Chloro-4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline chemical structure, C16H16ClNO, CAS 110014-07-8
4-(3-Chloro-4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline
CAS 110014-07-8C16H16ClNO
8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-4-ol chemical structure, C16H18N2O, CAS 113527-33-6
8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-4-ol
CAS 113527-33-6C16H18N2O
7,8-Dihydroxy-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline chemical structure, C15H15NO4, CAS 119085-25-5
7,8-Dihydroxy-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline
CAS 119085-25-5C15H15NO4
6-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline chemical structure, C16H17N, CAS 133390-36-0
6-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline
CAS 133390-36-0C16H17N
6,7-Dimethoxy-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline chemical structure, C18H21NO2, CAS 128942-65-4
6,7-Dimethoxy-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline
CAS 128942-65-4C18H21NO2
4-Phenyl-1,2,3,4-tetrahydroisoquinolin-4-ol chemical structure, C15H15NO, CAS 157017-51-1
4-Phenyl-1,2,3,4-tetrahydroisoquinolin-4-ol
CAS 157017-51-1C15H15NO
2-Methyl-4-(4-methylphenyl)-1,2,3,4-tetrahydroisoquinolin-8-amine chemical structure, C17H20N2, CAS 89543-62-4
2-Methyl-4-(4-methylphenyl)-1,2,3,4-tetrahydroisoquinolin-8-amine
CAS 89543-62-4C17H20N2
3-tert-Butyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline chemical structure, C19H23N, CAS 55792-04-6
3-tert-Butyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline
CAS 55792-04-6C19H23N
4-(4-Chlorophenyl)-1,2,3,4-tetrahydro-2-methyl-7-isoquinolinol chemical structure, C16H16ClNO, CAS 34041-71-9
4-(4-Chlorophenyl)-1,2,3,4-tetrahydro-2-methyl-7-isoquinolinol
CAS 34041-71-9C16H16ClNO
7-Isoquinolinol, 2-acetyl-1,2,3,4-tetrahydro-4-(4-hydroxyphenyl)-6-methoxy-, (S)- chemical structure, C18H19NO4, CAS 56771-98-3
7-Isoquinolinol, 2-acetyl-1,2,3,4-tetrahydro-4-(4-hydroxyphenyl)-6-methoxy-, (S)-
CAS 56771-98-3C18H19NO4
3-(6,8-Dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzoic acid chemical structure, C17H15Cl2NO2, CAS 543737-13-9
3-(6,8-Dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzoic acid
CAS 543737-13-9C17H15Cl2NO2
4-(3-Bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride chemical structure, C16H15BrCl3N, CAS 543739-81-7
4-(3-Bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride
CAS 543739-81-7C16H15BrCl3N
4-(3-Bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline chemical structure, C16H14BrCl2N, CAS 543737-10-6
4-(3-Bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline
CAS 543737-10-6C16H14BrCl2N
Diclofensine, (R)- chemical structure, C17H17Cl2NO, CAS 50560-45-7
Diclofensine, (R)-
CAS 50560-45-7C17H17Cl2NO
Diclofensine, (S)- chemical structure, C17H17Cl2NO, CAS 50560-38-8
Diclofensine, (S)-
CAS 50560-38-8C17H17Cl2NO
4-(4-Hydroxy-3-methylphenyl)-7-methoxy-1,2,3,4-tetrahydroisoquinolin-8-ol--hydrogen chloride (1/1) chemical structure, C17H20ClNO3, CAS 23230-77-5
4-(4-Hydroxy-3-methylphenyl)-7-methoxy-1,2,3,4-tetrahydroisoquinolin-8-ol--hydrogen chloride (1/1)
CAS 23230-77-5C17H20ClNO3
6,7-Dimethoxy-4-phenyl 1,2,3,4-tetrahydroisoquinoline hydrocholoride chemical structure, C17H20ClNO2, CAS 78238-94-5
6,7-Dimethoxy-4-phenyl 1,2,3,4-tetrahydroisoquinoline hydrocholoride
CAS 78238-94-5C17H20ClNO2
Acetamide, 2-(ethylamino)-N-(1,2,3,4-tetrahydro-4-(p-chlorophenyl)-2-methyl-8-isoquinolinyl)-, maleate chemical structure, C24H28ClN3O5, CAS 91454-41-0
Acetamide, 2-(ethylamino)-N-(1,2,3,4-tetrahydro-4-(p-chlorophenyl)-2-methyl-8-isoquinolinyl)-, maleate
CAS 91454-41-0C24H28ClN3O5
Acetamide, 2-(ethylamino)-N-(1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolinyl)-, maleate chemical structure, C24H29N3O5, CAS 91454-23-8
Acetamide, 2-(ethylamino)-N-(1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolinyl)-, maleate
CAS 91454-23-8C24H29N3O5
Acetamide, 2-(ethylamino)-N-(1,2,3,4-tetrahydro-2-methyl-4-p-tolyl-8-isoquinolinyl)-, maleate chemical structure, C25H31N3O5, CAS 91454-45-4
Acetamide, 2-(ethylamino)-N-(1,2,3,4-tetrahydro-2-methyl-4-p-tolyl-8-isoquinolinyl)-, maleate
CAS 91454-45-4C25H31N3O5
Acetamide, 2-(isopropylamino)-N-(1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolinyl)-, maleate chemical structure, C25H31N3O5, CAS 91454-25-0
Acetamide, 2-(isopropylamino)-N-(1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolinyl)-, maleate
CAS 91454-25-0C25H31N3O5
(S)-6,7-Dimethoxy-4-phenyl-1,2,3,4-tetrahydroisoquinoline chemical structure, C17H19NO2, CAS 139560-06-8
(S)-6,7-Dimethoxy-4-phenyl-1,2,3,4-tetrahydroisoquinoline
CAS 139560-06-8C17H19NO2
Selandopam hydrochloride hydrate chemical structure, C15H18ClNO5, CAS 138086-00-7
Selandopam hydrochloride hydrate
CAS 138086-00-7C15H18ClNO5