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Murcko scaffold

4-Phenyl-1,2,3,4-tetrahydro-isoquinoline scaffold

112 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
112
With full pages
18
Scaffold SMILES

c1ccc(C2CNCc3ccccc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenyl-1,2,3,4-tetrahydro-isoquinoline page
Murcko scaffold c1ccc(C2CNCc3ccccc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 112 of 112 chemicals

6-Chloro-4-phenyl-1,2,3,4-tetrahydroisoquinoline chemical structure, C15H14ClN, CAS 1344692-70-1
6-Chloro-4-phenyl-1,2,3,4-tetrahydroisoquinoline
CAS 1344692-70-1C15H14ClN
4-(4-Fluorophenyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride chemical structure, C15H15ClFN, CAS 1231254-47-9
4-(4-Fluorophenyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride
CAS 1231254-47-9C15H15ClFN
4-(4-Methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride chemical structure, C16H18ClNO, CAS 1231254-48-0
4-(4-Methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride
CAS 1231254-48-0C16H18ClNO
4-(2-Methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride chemical structure, C16H18ClNO, CAS 2098032-70-1
4-(2-Methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride
CAS 2098032-70-1C16H18ClNO
(S)-4-(3-Bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride chemical structure, C16H15BrCl3N, CAS 2306247-91-4
(S)-4-(3-Bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride
CAS 2306247-91-4C16H15BrCl3N
7-Methoxy-4-(4-methylphenyl)-1,2,3,4-tetrahydroisoquinoline chemical structure, C17H19NO, CAS 746542-81-4
7-Methoxy-4-(4-methylphenyl)-1,2,3,4-tetrahydroisoquinoline
CAS 746542-81-4C17H19NO
Nomifensine N-hydroxylamine chemical structure, C16H18N2O, CAS 1311205-35-2
Nomifensine N-hydroxylamine
CAS 1311205-35-2C16H18N2O
6-Bromo-4-phenyl-1,2,3,4-tetrahydroisoquinoline chemical structure, C15H14BrN, CAS 2121100-47-6
6-Bromo-4-phenyl-1,2,3,4-tetrahydroisoquinoline
CAS 2121100-47-6C15H14BrN
(S)-4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride chemical structure, C15H16ClN, CAS 2322690-99-1
(S)-4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride
CAS 2322690-99-1C15H16ClN
Nomifensine-d3 (maleate) chemical structure, C20H22N2O4, CAS 1795140-41-8
Nomifensine-d3 (maleate)
CAS 1795140-41-8C20H22N2O4
Nomifensine hydrochloride, (R)- chemical structure, C16H19ClN2, CAS 106976-99-2
Nomifensine hydrochloride, (R)-
CAS 106976-99-2C16H19ClN2
Nomifensine hydrochloride, (S)- chemical structure, C16H19ClN2, CAS 106976-98-1
Nomifensine hydrochloride, (S)-
CAS 106976-98-1C16H19ClN2
4-(4-Methylphenyl)-1,2,3,4-tetrahydroisoquinolinehydrochloride chemical structure, C16H18ClN, CAS 1231254-49-1
4-(4-Methylphenyl)-1,2,3,4-tetrahydroisoquinolinehydrochloride
CAS 1231254-49-1C16H18ClN
tert-Butyl 4-(4-methylphenyl)-1,2,3,4-tetrahydroisoquinoline-2-carboxylate chemical structure, C21H25NO2, CAS 2803846-40-2
tert-Butyl 4-(4-methylphenyl)-1,2,3,4-tetrahydroisoquinoline-2-carboxylate
CAS 2803846-40-2C21H25NO2
Nomifensine-d3 maleic acid salt chemical structure, C20H22N2O4
Nomifensine-d3 maleic acid salt
C20H22N2O4
Tenapanor impurity 2 chemical structure, C16H15BrCl3N, CAS 2200552-25-4
Tenapanor impurity 2
CAS 2200552-25-4C16H15BrCl3N