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Murcko scaffold

Ring system with 3 rings and 20 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
12
With full pages
3
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc2[nH]ccc(=O)c2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccc2[nH]ccc(=O)c2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

4-Hydroxy-2-methyl-N-(m-tolyl)quinoline-6-carboxamide chemical structure, C18H16N2O2, CAS 940983-96-0
4-Hydroxy-2-methyl-N-(m-tolyl)quinoline-6-carboxamide
CAS 940983-96-0C18H16N2O2
4-Hydroxy-N-(2-methoxyphenyl)-2-methylquinoline-6-carboxamide chemical structure, C18H16N2O3, CAS 941252-05-7
4-Hydroxy-N-(2-methoxyphenyl)-2-methylquinoline-6-carboxamide
CAS 941252-05-7C18H16N2O3
N-(4-Methoxyphenyl)-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxamide chemical structure, C18H16N2O3, CAS 1015559-79-1
N-(4-Methoxyphenyl)-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxamide
CAS 1015559-79-1C18H16N2O3
N-(2,5-Dimethoxyphenyl)-4-hydroxy-2-methylquinoline-6-carboxamide chemical structure, C19H18N2O4, CAS 1010886-26-6
N-(2,5-Dimethoxyphenyl)-4-hydroxy-2-methylquinoline-6-carboxamide
CAS 1010886-26-6C19H18N2O4
4-[(4-Hydroxy-2-methyl-6-quinolyl)carbonylamino]benzamide chemical structure, C18H15N3O3, CAS 1010927-86-2
4-[(4-Hydroxy-2-methyl-6-quinolyl)carbonylamino]benzamide
CAS 1010927-86-2C18H15N3O3
N-(3-Acetylphenyl)-4-hydroxy-2-methylquinoline-6-carboxamide chemical structure, C19H16N2O3, CAS 1010879-13-6
N-(3-Acetylphenyl)-4-hydroxy-2-methylquinoline-6-carboxamide
CAS 1010879-13-6C19H16N2O3
N-(2,5-Dimethoxyphenyl)-1-ethyl-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxamide chemical structure, C21H22N2O4, CAS 1010904-29-6
N-(2,5-Dimethoxyphenyl)-1-ethyl-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxamide
CAS 1010904-29-6C21H22N2O4
1-Ethyl-N-(2-methoxyphenyl)-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxamide chemical structure, C20H20N2O3, CAS 1010923-33-7
1-Ethyl-N-(2-methoxyphenyl)-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxamide
CAS 1010923-33-7C20H20N2O3
N-(4-Acetylphenyl)-1-ethyl-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxamide chemical structure, C21H20N2O3, CAS 1010908-07-2
N-(4-Acetylphenyl)-1-ethyl-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxamide
CAS 1010908-07-2C21H20N2O3
1-Ethyl-N-(3-methoxyphenyl)-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxamide chemical structure, C20H20N2O3, CAS 1010908-37-8
1-Ethyl-N-(3-methoxyphenyl)-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxamide
CAS 1010908-37-8C20H20N2O3
N-(3-Acetylphenyl)-1-ethyl-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxamide chemical structure, C21H20N2O3, CAS 1010917-12-0
N-(3-Acetylphenyl)-1-ethyl-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxamide
CAS 1010917-12-0C21H20N2O3
Methyl 4-{[(1-ethyl-2-methyl-4-oxo-1,4-dihydroquinolin-6-yl)carbonyl]amino}benzoate chemical structure, C21H20N2O4, CAS 1010890-95-5
Methyl 4-{[(1-ethyl-2-methyl-4-oxo-1,4-dihydroquinolin-6-yl)carbonyl]amino}benzoate
CAS 1010890-95-5C21H20N2O4