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Murcko scaffold

Ring system with 3 rings and 22 atoms

20 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 22
Chemicals: 20
With full pages: 3

Scaffold SMILES

O=C(COc1ccccc1)Nc1cnc2ccccn2c1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(COc1ccccc1)Nc1cnc2ccccn2c1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

N-(2-Methyl-4-oxopyrido[1,2-a]pyrimidin-3-yl)-2-phenoxyacetamide chemical structure, C17H15N3O3, CAS 897616-54-5

N-(2-Methyl-4-oxopyrido[1,2-a]pyrimidin-3-yl)-2-phenoxyacetamide

CAS 897616-54-5C₁₇H₁₅N₃O₃

2-(2,4-Dichlorophenoxy)-N-(2,8-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acetamide chemical structure, C18H15Cl2N3O3, CAS 897616-93-2

2-(2,4-Dichlorophenoxy)-N-(2,8-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acetamide

CAS 897616-93-2C₁₈H₁₅Cl₂N₃O₃

N-(2,8-Dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-phenoxyacetamide chemical structure, C18H17N3O3, CAS 897617-07-1

N-(2,8-Dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-phenoxyacetamide

CAS 897617-07-1C₁₈H₁₇N₃O₃

N-(2,7-Dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-phenoxyacetamide chemical structure, C18H17N3O3, CAS 941965-78-2

N-(2,7-Dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-phenoxyacetamide

CAS 941965-78-2C₁₈H₁₇N₃O₃

2-(4-Chlorophenoxy)-N-{2,7-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide chemical structure, C18H16ClN3O3, CAS 941923-63-3

2-(4-Chlorophenoxy)-N-{2,7-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide

CAS 941923-63-3C₁₈H₁₆ClN₃O₃

2-(2,4-Dichlorophenoxy)-N-{2,6-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide chemical structure, C18H15Cl2N3O3, CAS 941876-02-4

2-(2,4-Dichlorophenoxy)-N-{2,6-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide

CAS 941876-02-4C₁₈H₁₅Cl₂N₃O₃

2-(2,4-Dichlorophenoxy)-N-{2,9-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide chemical structure, C18H15Cl2N3O3, CAS 942001-28-7

2-(2,4-Dichlorophenoxy)-N-{2,9-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide

CAS 942001-28-7C₁₈H₁₅Cl₂N₃O₃

N-{2,9-Dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}-2-phenoxyacetamide chemical structure, C18H17N3O3, CAS 941965-54-4

N-{2,9-Dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}-2-phenoxyacetamide

CAS 941965-54-4C₁₈H₁₇N₃O₃

2-(4-Chlorophenoxy)-N-{2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide chemical structure, C17H14ClN3O3, CAS 946335-77-9

2-(4-Chlorophenoxy)-N-{2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide

CAS 946335-77-9C₁₇H₁₄ClN₃O₃

2-(4-Chlorophenoxy)-N-{2,8-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide chemical structure, C18H16ClN3O3, CAS 946381-80-2

2-(4-Chlorophenoxy)-N-{2,8-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide

CAS 946381-80-2C₁₈H₁₆ClN₃O₃

2-(4-Acetyl-2-methoxyphenoxy)-N-{2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide chemical structure, C20H19N3O5, CAS 1060292-97-8

2-(4-Acetyl-2-methoxyphenoxy)-N-{2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide

CAS 1060292-97-8C₂₀H₁₉N₃O₅

N-{2-Methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}-2-[3-(trifluoromethyl)phenoxy]acetamide chemical structure, C18H14F3N3O3, CAS 1060329-60-3

N-{2-Methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}-2-[3-(trifluoromethyl)phenoxy]acetamide

CAS 1060329-60-3C₁₈H₁₄F₃N₃O₃

2-(2,5-Dimethylphenoxy)-N-{2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}propanamide chemical structure, C20H21N3O3, CAS 1060244-76-9

2-(2,5-Dimethylphenoxy)-N-{2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}propanamide

CAS 1060244-76-9C₂₀H₂₁N₃O₃

2-(2-Fluorophenoxy)-N-(2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)propanamide chemical structure, C18H16FN3O3, CAS 1060293-88-0

2-(2-Fluorophenoxy)-N-(2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)propanamide

CAS 1060293-88-0C₁₈H₁₆FN₃O₃

2-(4-Acetyl-2-methoxyphenoxy)-N-{2,8-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide chemical structure, C21H21N3O5, CAS 1060246-13-0

2-(4-Acetyl-2-methoxyphenoxy)-N-{2,8-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide

CAS 1060246-13-0C₂₁H₂₁N₃O₅

N-(2,8-Dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-(3,4-dimethylphenoxy)propanamide chemical structure, C21H23N3O3, CAS 1060281-00-6

N-(2,8-Dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-(3,4-dimethylphenoxy)propanamide

CAS 1060281-00-6C₂₁H₂₃N₃O₃

N-(2,7-Dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-(2-fluorophenoxy)propanamide chemical structure, C19H18FN3O3, CAS 1060283-31-9

N-(2,7-Dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-(2-fluorophenoxy)propanamide

CAS 1060283-31-9C₁₉H₁₈FN₃O₃

2-(4-Acetyl-2-methoxyphenoxy)-N-{7-chloro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide chemical structure, C20H18ClN3O5, CAS 1060348-37-9

2-(4-Acetyl-2-methoxyphenoxy)-N-{7-chloro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}acetamide

CAS 1060348-37-9C₂₀H₁₈ClN₃O₅

N-(7-Chloro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-(2,5-dimethylphenoxy)propanamide chemical structure, C20H20ClN3O3, CAS 1060289-97-5

N-(7-Chloro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-(2,5-dimethylphenoxy)propanamide

CAS 1060289-97-5C₂₀H₂₀ClN₃O₃

N-(7-Chloro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-(3-fluorophenoxy)propanamide chemical structure, C18H15ClFN3O3, CAS 1070960-06-3

N-(7-Chloro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-(3-fluorophenoxy)propanamide

CAS 1070960-06-3C₁₈H₁₅ClFN₃O₃