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Murcko scaffold

Ring system with 2 rings and 15 atoms

143 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
143
With full pages
31
Scaffold SMILES

C(=Nc1ncccn1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Nc1ncccn1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 143 chemicals

1-(4,6-Dimethylpyrimidin-2-yl)-3-(3-hydroxyphenyl)guanidine chemical structure, C13H15N5O, CAS 351190-45-9
1-(4,6-Dimethylpyrimidin-2-yl)-3-(3-hydroxyphenyl)guanidine
CAS 351190-45-9C13H15N5O
1-(4,6-Dimethylpyrimidin-2-yl)-3-(4-ethoxyphenyl)guanidine chemical structure, C15H19N5O, CAS 34747-53-0
1-(4,6-Dimethylpyrimidin-2-yl)-3-(4-ethoxyphenyl)guanidine
CAS 34747-53-0C15H19N5O
1-(4-Butylphenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine chemical structure, C17H23N5, CAS 332073-85-5
1-(4-Butylphenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine
CAS 332073-85-5C17H23N5
1-(3,5-Dimethylphenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine chemical structure, C15H19N5, CAS 332073-86-6
1-(3,5-Dimethylphenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine
CAS 332073-86-6C15H19N5
N-({4-[N'-(4,6-dimethylpyrimidin-2-yl)carbamimidamido]phenyl}sulfonyl)acetamide chemical structure, C15H18N6O3S
N-({4-[N'-(4,6-dimethylpyrimidin-2-yl)carbamimidamido]phenyl}sulfonyl)acetamide
C15H18N6O3S
1-(4,6-Dimethylpyrimidin-2-yl)-3-(3-nitrophenyl)guanidine chemical structure, C13H14N6O2, CAS 332144-44-2
1-(4,6-Dimethylpyrimidin-2-yl)-3-(3-nitrophenyl)guanidine
CAS 332144-44-2C13H14N6O2
1-(4,6-Dimethylpyrimidin-2-yl)-3-(2-methyl-4-nitrophenyl)guanidine chemical structure, C14H16N6O2, CAS 332144-43-1
1-(4,6-Dimethylpyrimidin-2-yl)-3-(2-methyl-4-nitrophenyl)guanidine
CAS 332144-43-1C14H16N6O2
2-(4,6-Dimethylpyrimidin-2-yl)-1-(2-methyl-5-nitrophenyl)guanidine chemical structure, C14H16N6O2, CAS 337494-04-9
2-(4,6-Dimethylpyrimidin-2-yl)-1-(2-methyl-5-nitrophenyl)guanidine
CAS 337494-04-9C14H16N6O2
2-(4,6-Dimethylpyrimidin-2-yl)-1-(4-methyl-3-nitrophenyl)guanidine chemical structure, C14H16N6O2, CAS 337494-07-2
2-(4,6-Dimethylpyrimidin-2-yl)-1-(4-methyl-3-nitrophenyl)guanidine
CAS 337494-07-2C14H16N6O2
1-(4,6-Dimethylpyrimidin-2-yl)-3-(2-hydroxyphenyl)guanidine chemical structure, C13H15N5O, CAS 354993-68-3
1-(4,6-Dimethylpyrimidin-2-yl)-3-(2-hydroxyphenyl)guanidine
CAS 354993-68-3C13H15N5O
2-(4,6-Dimethylpyrimidin-2-yl)-1-(2-methoxy-4-nitrophenyl)guanidine chemical structure, C14H16N6O3, CAS 364625-13-8
2-(4,6-Dimethylpyrimidin-2-yl)-1-(2-methoxy-4-nitrophenyl)guanidine
CAS 364625-13-8C14H16N6O3
1-(2,4-Dimethoxyphenyl)-2-(4,6-dimethylpyrimidin-2-yl)guanidine chemical structure, C15H19N5O2, CAS 354993-66-1
1-(2,4-Dimethoxyphenyl)-2-(4,6-dimethylpyrimidin-2-yl)guanidine
CAS 354993-66-1C15H19N5O2
1-(5-Chloro-2-methylphenyl)-2-(4,6-dimethylpyrimidin-2-yl)guanidine chemical structure, C14H16ClN5, CAS 354993-65-0
1-(5-Chloro-2-methylphenyl)-2-(4,6-dimethylpyrimidin-2-yl)guanidine
CAS 354993-65-0C14H16ClN5
2-(4,6-Dimethylpyrimidin-2-yl)-1-(2-nitrophenyl)guanidine chemical structure, C13H14N6O2, CAS 374617-46-6
2-(4,6-Dimethylpyrimidin-2-yl)-1-(2-nitrophenyl)guanidine
CAS 374617-46-6C13H14N6O2
4-(N'-(4,6-Dimethylpyrimidin-2-yl)formohydrazonamido)benzoic acid chemical structure, C14H15N5O2
4-(N'-(4,6-Dimethylpyrimidin-2-yl)formohydrazonamido)benzoic acid
C14H15N5O2
4-(3-(4,6-Dimethylpyrimidin-2-yl)guanidino)benzenesulfonic acid chemical structure, C13H15N5O3S, CAS 352659-32-6
4-(3-(4,6-Dimethylpyrimidin-2-yl)guanidino)benzenesulfonic acid
CAS 352659-32-6C13H15N5O3S
N-{3-[N'-(4,6-dimethylpyrimidin-2-yl)carbamimidamido]phenyl}acetamide chemical structure, C15H18N6O, CAS 364602-61-9
N-{3-[N'-(4,6-dimethylpyrimidin-2-yl)carbamimidamido]phenyl}acetamide
CAS 364602-61-9C15H18N6O
1-(2,5-Dimethylphenyl)-2-(4,6-dimethylpyrimidin-2-yl)guanidine chemical structure, C15H19N5, CAS 372493-50-0
1-(2,5-Dimethylphenyl)-2-(4,6-dimethylpyrimidin-2-yl)guanidine
CAS 372493-50-0C15H19N5
Propan-2-yl {4-[N'-(4,6-dimethylpyrimidin-2-yl)carbamimidamido]phenyl}acetate chemical structure, C18H23N5O2, CAS 443321-86-6
Propan-2-yl {4-[N'-(4,6-dimethylpyrimidin-2-yl)carbamimidamido]phenyl}acetate
CAS 443321-86-6C18H23N5O2
1-(4-Chloro-2,5-dimethoxyphenyl)-2-(4,6-dimethylpyrimidin-2-yl)guanidine chemical structure, C15H18ClN5O2, CAS 511515-12-1
1-(4-Chloro-2,5-dimethoxyphenyl)-2-(4,6-dimethylpyrimidin-2-yl)guanidine
CAS 511515-12-1C15H18ClN5O2
Dimethyl 5-(3-(4,6-dimethylpyrimidin-2-yl)guanidino)isophthalate chemical structure, C17H19N5O4, CAS 524057-28-1
Dimethyl 5-(3-(4,6-dimethylpyrimidin-2-yl)guanidino)isophthalate
CAS 524057-28-1C17H19N5O4
N-(3,5-Dimethoxy-phenyl)-N'-(4,6-dimethyl-pyrimidin-2-yl)-guanidine chemical structure, C15H19N5O2, CAS 524057-27-0
N-(3,5-Dimethoxy-phenyl)-N'-(4,6-dimethyl-pyrimidin-2-yl)-guanidine
CAS 524057-27-0C15H19N5O2
N-(2-Bromophenyl)-N'-(4,6-dimethylpyrimidin-2-yl)guanidine chemical structure, C13H14BrN5, CAS 524057-23-6
N-(2-Bromophenyl)-N'-(4,6-dimethylpyrimidin-2-yl)guanidine
CAS 524057-23-6C13H14BrN5
N-(3-Chloro-4-fluorophenyl)-N'-(4,6-dimethylpyrimidin-2-yl)guanidine chemical structure, C13H13ClFN5, CAS 524057-25-8
N-(3-Chloro-4-fluorophenyl)-N'-(4,6-dimethylpyrimidin-2-yl)guanidine
CAS 524057-25-8C13H13ClFN5