CompoundList
Sign in
Murcko scaffold

6,10-Dioxaspiro[4.5]decane scaffold

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
22
With full pages
3
Scaffold SMILES

C1COC2(CCCC2)OC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6,10-Dioxaspiro[4.5]decane page
Murcko scaffold C1COC2(CCCC2)OC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

5,5-Dimethyl-1,3-dioxane-2-spirocyclopentane chemical structure, C10H18O2, CAS 702-75-0
5,5-Dimethyl-1,3-dioxane-2-spirocyclopentane
CAS 702-75-0C10H18O2
7-Methyl-6,10-dioxaspiro[4.5]decane chemical structure, C9H16O2, CAS 5413-44-5
7-Methyl-6,10-dioxaspiro[4.5]decane
CAS 5413-44-5C9H16O2
7,9-Dimethyl-6,10-dioxaspiro[4.5]decane chemical structure, C10H18O2, CAS 6413-22-5
7,9-Dimethyl-6,10-dioxaspiro[4.5]decane
CAS 6413-22-5C10H18O2
8-Ethyl-7-propyl-6,10-dioxaspiro[4.5]decane chemical structure, C13H24O2, CAS 5421-08-9
8-Ethyl-7-propyl-6,10-dioxaspiro[4.5]decane
CAS 5421-08-9C13H24O2
8-Methyl-8-nitro-6,10-dioxaspiro[4.5]decane chemical structure, C9H15NO4, CAS 6282-90-2
8-Methyl-8-nitro-6,10-dioxaspiro[4.5]decane
CAS 6282-90-2C9H15NO4
8-Butyl-8-ethyl-6,10-dioxaspiro[4.5]decane chemical structure, C14H26O2, CAS 6471-99-4
8-Butyl-8-ethyl-6,10-dioxaspiro[4.5]decane
CAS 6471-99-4C14H26O2
8,8-Diethyl-6,10-dioxaspiro[4.5]decane chemical structure, C12H22O2, CAS 24571-14-0
8,8-Diethyl-6,10-dioxaspiro[4.5]decane
CAS 24571-14-0C12H22O2
6,10-Dioxaspiro[4.5]decane, 8,8-dimethyl-7-(1-methylethyl)- chemical structure, C13H24O2, CAS 62406-73-9
6,10-Dioxaspiro[4.5]decane, 8,8-dimethyl-7-(1-methylethyl)-
CAS 62406-73-9C13H24O2
8-Ethyl-8-nitro-6,10-dioxaspiro[4.5]decane chemical structure, C10H17NO4, CAS 6413-68-9
8-Ethyl-8-nitro-6,10-dioxaspiro[4.5]decane
CAS 6413-68-9C10H17NO4
(7R,9R)-7,9-Dimethyl-6,10-dioxaspiro[4.5]decane chemical structure, C10H18O2, CAS 128993-92-0
(7R,9R)-7,9-Dimethyl-6,10-dioxaspiro[4.5]decane
CAS 128993-92-0C10H18O2
8,8-Dimethyl-6,10-dioxaspiro[4.5]decane-2-carboxylic acid chemical structure, C11H18O4, CAS 159644-55-0
8,8-Dimethyl-6,10-dioxaspiro[4.5]decane-2-carboxylic acid
CAS 159644-55-0C11H18O4
6,10-Dioxaspiro[4.5]decane chemical structure, C8H14O2, CAS 177-35-5
6,10-Dioxaspiro[4.5]decane
CAS 177-35-5C8H14O2
1,1-Dimethylethyl (7R,9R)-9-(cyanomethyl)-6,10-dioxaspiro(4.5)decane-7-acetate chemical structure, C16H25NO4, CAS 1035204-82-0
1,1-Dimethylethyl (7R,9R)-9-(cyanomethyl)-6,10-dioxaspiro(4.5)decane-7-acetate
CAS 1035204-82-0C16H25NO4
1,1-Dimethylethyl (7R,9R)-9-(2-aminoethyl)-6,10-dioxaspiro[4.5]decane-7-acetate chemical structure, C16H29NO4, CAS 125988-02-5
1,1-Dimethylethyl (7R,9R)-9-(2-aminoethyl)-6,10-dioxaspiro[4.5]decane-7-acetate
CAS 125988-02-5C16H29NO4
(7S,9R)-7,9-Dimethyl-6,10-dioxaspiro[4.5]decane chemical structure, C10H18O2, CAS 128994-14-9
(7S,9R)-7,9-Dimethyl-6,10-dioxaspiro[4.5]decane
CAS 128994-14-9C10H18O2
(8-Methyl-6,10-dioxaspiro[4.5]dec-8-yl)amine chemical structure, C9H17NO2, CAS 873379-68-1
(8-Methyl-6,10-dioxaspiro[4.5]dec-8-yl)amine
CAS 873379-68-1C9H17NO2
(S)-8,8-Dimethyl-6,10-dioxaspiro[4.5]decane-2-carboxylic acid chemical structure, C11H18O4, CAS 159701-41-4
(S)-8,8-Dimethyl-6,10-dioxaspiro[4.5]decane-2-carboxylic acid
CAS 159701-41-4C11H18O4
6,10-Dioxaspiro[4.5]dec-8-ylmethanol chemical structure, C9H16O3, CAS 4933-22-6
6,10-Dioxaspiro[4.5]dec-8-ylmethanol
CAS 4933-22-6C9H16O3
2,8,8-Trimethyl-7-(propan-2-yl)-6,10-dioxaspiro[4.5]decane chemical structure, C14H26O2, CAS 62406-75-1
2,8,8-Trimethyl-7-(propan-2-yl)-6,10-dioxaspiro[4.5]decane
CAS 62406-75-1C14H26O2
6,10-Dioxaspiro[4.5]decan-8-amine chemical structure, C8H15NO2, CAS 1519815-95-2
6,10-Dioxaspiro[4.5]decan-8-amine
CAS 1519815-95-2C8H15NO2
(S)-1-Phenylethan-1-amine (S)-8,8-dimethyl-6,10-dioxaspiro[4.5]decane-2-carboxylate chemical structure, C19H29NO4, CAS 159701-43-6
(S)-1-Phenylethan-1-amine (S)-8,8-dimethyl-6,10-dioxaspiro[4.5]decane-2-carboxylate
CAS 159701-43-6C19H29NO4
(1S,2S)-1-(2-Bromoethyl)-2-ethenyl-1,8,8-trimethyl-6,10-dioxaspiro[4.5]decane chemical structure, C15H25BrO2, CAS 114673-86-8
(1S,2S)-1-(2-Bromoethyl)-2-ethenyl-1,8,8-trimethyl-6,10-dioxaspiro[4.5]decane
CAS 114673-86-8C15H25BrO2