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Murcko scaffold

Ring system with 3 rings and 20 atoms

4 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
4
With full pages
4
Scaffold SMILES

O=C(Cc1ccccc1)N1N=CCC1c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)N1N=CCC1c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

1-(5-Hydroxy-3-methyl-5-pyridin-3-yl-4H-pyrazol-1-yl)-2-phenylethanone chemical structure, C17H17N3O2, CAS 301321-64-2
1-(5-Hydroxy-3-methyl-5-pyridin-3-yl-4H-pyrazol-1-yl)-2-phenylethanone
CAS 301321-64-2C17H17N3O2
1-(5-Hydroxy-3-methyl-5-pyridin-3-yl-4H-pyrazol-1-yl)-2-(4-nitrophenyl)ethanone chemical structure, C17H16N4O4, CAS 312520-26-6
1-(5-Hydroxy-3-methyl-5-pyridin-3-yl-4H-pyrazol-1-yl)-2-(4-nitrophenyl)ethanone
CAS 312520-26-6C17H16N4O4
1-[5-Hydroxy-3-methyl-5-(3-pyridinyl)-4H-pyrazol-1-yl]-2-(4-methylphenyl)ethanone chemical structure, C18H19N3O2, CAS 296887-91-7
1-[5-Hydroxy-3-methyl-5-(3-pyridinyl)-4H-pyrazol-1-yl]-2-(4-methylphenyl)ethanone
CAS 296887-91-7C18H19N3O2
2-(3,4-Dimethoxyphenyl)-1-(5-hydroxy-3-methyl-5-pyridin-3-yl-4H-pyrazol-1-yl)ethanone chemical structure, C19H21N3O4, CAS 312533-28-1
2-(3,4-Dimethoxyphenyl)-1-(5-hydroxy-3-methyl-5-pyridin-3-yl-4H-pyrazol-1-yl)ethanone
CAS 312533-28-1C19H21N3O4