Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-4'-one scaffold

27 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 13
Chemicals: 27
With full pages: 1

Scaffold SMILES

O=C1CCC2(CC2)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-4'-one page

Murcko scaffold O=C1CCC2(CC2)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

6'-Bromo-2',3'-dihydro-4'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C12H11BrO, CAS 1781457-40-6

6'-Bromo-2',3'-dihydro-4'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 1781457-40-6C₁₂H₁₁BrO

3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-4'-one chemical structure, C12H12O, CAS 67688-27-1

3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-4'-one

CAS 67688-27-1C₁₂H₁₂O

5',7'-Difluoro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-4'-one chemical structure, C12H10F2O, CAS 2167089-74-7

5',7'-Difluoro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-4'-one

CAS 2167089-74-7C₁₂H₁₀F₂O

3,3-Difluoro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-4'-one chemical structure, C12H10F2O, CAS 2243514-80-7

3,3-Difluoro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-4'-one

CAS 2243514-80-7C₁₂H₁₀F₂O

5'-Chloro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C12H11ClO, CAS 2169524-39-2

5'-Chloro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2169524-39-2C₁₂H₁₁ClO

7'-Ethyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C14H16O, CAS 2167542-16-5

7'-Ethyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2167542-16-5C₁₄H₁₆O

5'-Bromo-7'-methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C13H13BrO, CAS 2168636-03-9

5'-Bromo-7'-methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2168636-03-9C₁₃H₁₃BrO

7'-Bromo-5'-methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C13H13BrO, CAS 2169443-83-6

7'-Bromo-5'-methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2169443-83-6C₁₃H₁₃BrO

7'-(Dimethylamino)-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C14H17NO, CAS 2168846-53-3

7'-(Dimethylamino)-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2168846-53-3C₁₄H₁₇NO

7'-Chloro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C12H11ClO, CAS 2166731-32-2

7'-Chloro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2166731-32-2C₁₂H₁₁ClO

7'-Fluoro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C12H11FO, CAS 2168648-06-2

7'-Fluoro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2168648-06-2C₁₂H₁₁FO

7'-(Propan-2-yl)-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C15H18O, CAS 2167102-91-0

7'-(Propan-2-yl)-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2167102-91-0C₁₅H₁₈O

7'-Ethoxy-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C14H16O2, CAS 2169489-78-3

7'-Ethoxy-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2169489-78-3C₁₄H₁₆O₂

5'-Methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C13H14O, CAS 2167155-04-4

5'-Methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2167155-04-4C₁₃H₁₄O

7'-Methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C13H14O, CAS 2167671-24-9

7'-Methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2167671-24-9C₁₃H₁₄O

5'-Bromo-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C12H11BrO, CAS 2167198-51-6

5'-Bromo-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2167198-51-6C₁₂H₁₁BrO

6',8'-Dibromo-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C12H10Br2O, CAS 2166745-87-3

6',8'-Dibromo-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2166745-87-3C₁₂H₁₀Br₂O

5'-Fluoro-8'-methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C13H13FO, CAS 2167593-46-4

5'-Fluoro-8'-methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2167593-46-4C₁₃H₁₃FO

7'-(Trifluoromethyl)-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C13H11F3O, CAS 2172523-35-0

7'-(Trifluoromethyl)-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2172523-35-0C₁₃H₁₁F₃O

7'-Bromo-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-4'-one chemical structure, C12H11BrO, CAS 2168568-30-5

7'-Bromo-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-4'-one

CAS 2168568-30-5C₁₂H₁₁BrO

5'-Fluoro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C12H11FO, CAS 2167187-57-5

5'-Fluoro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2167187-57-5C₁₂H₁₁FO

7'-Fluoro-5'-methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C13H13FO, CAS 2166529-78-6

7'-Fluoro-5'-methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2166529-78-6C₁₃H₁₃FO

6',8'-Difluoro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C12H10F2O, CAS 2167304-67-6

6',8'-Difluoro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2167304-67-6C₁₂H₁₀F₂O

7'-(Diethylamino)-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one chemical structure, C16H21NO, CAS 2171834-97-0

7'-(Diethylamino)-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-one

CAS 2171834-97-0C₁₆H₂₁NO