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Murcko scaffold

Ring system with 3 rings and 12 atoms

56 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
12
Chemicals
56
With full pages
7
Scaffold SMILES

c1ccc2c(c1)CCCC21CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(c1)CCCC21CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 56 chemicals

3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-2'-amine chemical structure, C12H15N, CAS 1891305-41-1
3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-2'-amine
CAS 1891305-41-1C12H15N
3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-3-carboxylic acid chemical structure, C13H14O2, CAS 1248314-77-3
3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-3-carboxylic acid
CAS 1248314-77-3C13H14O2
4',4'-Dimethyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-2-amine chemical structure, C14H19N, CAS 1250115-55-9
4',4'-Dimethyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-2-amine
CAS 1250115-55-9C14H19N
3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-3-amine chemical structure, C12H15N, CAS 1250796-74-7
3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-3-amine
CAS 1250796-74-7C12H15N
(4',4'-Dimethyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-2-yl)methanamine chemical structure, C15H21N, CAS 1432792-63-6
(4',4'-Dimethyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-2-yl)methanamine
CAS 1432792-63-6C15H21N
(3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-2-yl)methanamine chemical structure, C13H17N, CAS 1342661-90-8
(3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-2-yl)methanamine
CAS 1342661-90-8C13H17N
3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-3-ylmethanamine hydrochloride chemical structure, C13H18ClN, CAS 1394040-37-9
3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-3-ylmethanamine hydrochloride
CAS 1394040-37-9C13H18ClN
4',4'-Dimethyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-2-amine hydrochloride chemical structure, C14H20ClN, CAS 1427380-49-1
4',4'-Dimethyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-2-amine hydrochloride
CAS 1427380-49-1C14H20ClN
4',4'-Dimethyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-2-ylmethanamine hydrochloride chemical structure, C15H22ClN, CAS 1432679-84-9
4',4'-Dimethyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-2-ylmethanamine hydrochloride
CAS 1432679-84-9C15H22ClN
3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-2-amine hydrochloride chemical structure, C12H16ClN, CAS 1375474-45-5
3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-2-amine hydrochloride
CAS 1375474-45-5C12H16ClN
7'-Bromo-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene] chemical structure, C12H13Br, CAS 1467345-82-9
7'-Bromo-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]
CAS 1467345-82-9C12H13Br
8'-Bromo-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene] chemical structure, C12H13Br, CAS 1781879-96-6
8'-Bromo-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]
CAS 1781879-96-6C12H13Br
3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-3-carboxamide chemical structure, C13H15NO, CAS 1444307-33-8
3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-3-carboxamide
CAS 1444307-33-8C13H15NO
rac-(1R,3S)-3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-3-amine chemical structure, C12H15N, CAS 2287249-12-9
rac-(1R,3S)-3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-3-amine
CAS 2287249-12-9C12H15N
rel-(1R,2S)-3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-2-carboxylic acid chemical structure, C13H14O2, CAS 1499188-88-3
rel-(1R,2S)-3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-2-carboxylic acid
CAS 1499188-88-3C13H14O2
rac-(1R,3R)-3',4'-Dihydro-2'H-spiro(cyclopropane-1,1'-naphthalene)-3-carboxylic acid chemical structure, C13H14O2, CAS 2287249-01-6
rac-(1R,3R)-3',4'-Dihydro-2'H-spiro(cyclopropane-1,1'-naphthalene)-3-carboxylic acid
CAS 2287249-01-6C13H14O2
rac-1-[(1R,3R)-3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-3-yl]methanamine chemical structure, C13H17N, CAS 2287236-87-5
rac-1-[(1R,3R)-3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-3-yl]methanamine
CAS 2287236-87-5C13H17N
rac-(1R,3R)-3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-3-carboxamide chemical structure, C13H15NO, CAS 2743228-24-0
rac-(1R,3R)-3',4'-Dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-3-carboxamide
CAS 2743228-24-0C13H15NO
(1'R,4R)-Spiro[2,3-dihydro-1H-naphthalene-4,2'-cyclopropane]-1'-carboxamide chemical structure, C13H15NO, CAS 2287237-23-2
(1'R,4R)-Spiro[2,3-dihydro-1H-naphthalene-4,2'-cyclopropane]-1'-carboxamide
CAS 2287237-23-2C13H15NO
7'-Bromo-spiro[cyclopropane-2,1'-tetralin]-1-amine chemical structure, C12H14BrN, CAS 1781099-65-7
7'-Bromo-spiro[cyclopropane-2,1'-tetralin]-1-amine
CAS 1781099-65-7C12H14BrN
6'-Bromo-spiro[cyclopropane-2,1'-tetralin]-1-amine chemical structure, C12H14BrN, CAS 1781081-32-0
6'-Bromo-spiro[cyclopropane-2,1'-tetralin]-1-amine
CAS 1781081-32-0C12H14BrN
(7'-Bromo-3',4'-dihydro-2'H-spiro(cyclopropane-1,1'-naphthalene)-3-yl)methanamine chemical structure, C13H16BrN, CAS 1781457-55-3
(7'-Bromo-3',4'-dihydro-2'H-spiro(cyclopropane-1,1'-naphthalene)-3-yl)methanamine
CAS 1781457-55-3C13H16BrN
6-Bromospiro[2,3-dihydro-1H-naphthalene-4,2'-cyclopropane]-1'-carboxylic acid chemical structure, C13H13BrO2, CAS 1784950-81-7
6-Bromospiro[2,3-dihydro-1H-naphthalene-4,2'-cyclopropane]-1'-carboxylic acid
CAS 1784950-81-7C13H13BrO2
6'-Bromo-spiro[cyclopropane-2,1-tetralin]-1-carboxylic acid chemical structure, C13H13BrO2, CAS 1780017-87-9
6'-Bromo-spiro[cyclopropane-2,1-tetralin]-1-carboxylic acid
CAS 1780017-87-9C13H13BrO2