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Murcko scaffold

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] scaffold

95 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 12
Chemicals: 95
With full pages: 7

Scaffold SMILES

c1ccc2c(c1)CNCC21CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] page

Murcko scaffold c1ccc2c(c1)CNCC21CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 95 chemicals

2'-Methyl-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinolin]-7'-amine chemical structure, C12H16N2, CAS 1092794-11-0

2'-Methyl-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinolin]-7'-amine

CAS 1092794-11-0C₁₂H₁₆N₂

5'-Chloro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] chemical structure, C11H12ClN, CAS 885269-14-7

5'-Chloro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]

CAS 885269-14-7C₁₁H₁₂ClN

5'-Methoxy-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] chemical structure, C12H15NO, CAS 885269-19-2

5'-Methoxy-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]

CAS 885269-19-2C₁₂H₁₅NO

6'-Chloro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] chemical structure, C11H12ClN, CAS 885269-22-7

6'-Chloro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]

CAS 885269-22-7C₁₁H₁₂ClN

6'-Methoxy-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] chemical structure, C12H15NO, CAS 885269-27-2

6'-Methoxy-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]

CAS 885269-27-2C₁₂H₁₅NO

7'-Chloro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] chemical structure, C11H12ClN, CAS 885269-29-4

7'-Chloro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]

CAS 885269-29-4C₁₁H₁₂ClN

7'-Methoxy-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] chemical structure, C12H15NO, CAS 885269-33-0

7'-Methoxy-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]

CAS 885269-33-0C₁₂H₁₅NO

8'-Chloro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] chemical structure, C11H12ClN, CAS 885269-35-2

8'-Chloro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]

CAS 885269-35-2C₁₁H₁₂ClN

8'-Methoxy-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] chemical structure, C12H15NO, CAS 885269-39-6

8'-Methoxy-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]

CAS 885269-39-6C₁₂H₁₅NO

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] chemical structure, C11H13N, CAS 1159010-39-5

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]

CAS 1159010-39-5C₁₁H₁₃N

2',3'-Dihydro-2'-methyl-7'-nitrospiro[cyclopropane-1,4'(1'H)-isoquinoline] chemical structure, C12H14N2O2, CAS 1092794-10-9

2',3'-Dihydro-2'-methyl-7'-nitrospiro[cyclopropane-1,4'(1'H)-isoquinoline]

CAS 1092794-10-9C₁₂H₁₄N₂O₂

7'-Nitro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] chemical structure, C11H12N2O2, CAS 561297-87-8

7'-Nitro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]

CAS 561297-87-8C₁₁H₁₂N₂O₂

2'-Methyl-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinolin]-7'-amine dihydrochloride chemical structure, C12H18Cl2N2, CAS 1092795-12-4

2'-Methyl-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinolin]-7'-amine dihydrochloride

CAS 1092795-12-4C₁₂H₁₈Cl₂N₂

Spiro[cyclopropane-1,4'(1'H)-isoquinoline], 2',3'-dihydro-2'-methyl-7'-nitro-, hydrochloride chemical structure, C12H15ClN2O2, CAS 1092795-11-3

Spiro[cyclopropane-1,4'(1'H)-isoquinoline], 2',3'-dihydro-2'-methyl-7'-nitro-, hydrochloride

CAS 1092795-11-3C₁₂H₁₅ClN₂O₂

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinolin]-7'-amine chemical structure, C11H14N2, CAS 1395030-56-4

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinolin]-7'-amine

CAS 1395030-56-4C₁₁H₁₄N₂

tert-Butyl 7'-amino-1'H-spiro[cyclopropane-1,4'-isoquinoline]-2'(3'H)-carboxylate chemical structure, C16H22N2O2, CAS 561297-88-9

tert-Butyl 7'-amino-1'H-spiro[cyclopropane-1,4'-isoquinoline]-2'(3'H)-carboxylate

CAS 561297-88-9C₁₆H₂₂N₂O₂

tert-Butyl 7'-bromo-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-2'-carboxylate chemical structure, C16H20BrNO2, CAS 1203684-92-7

tert-Butyl 7'-bromo-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-2'-carboxylate

CAS 1203684-92-7C₁₆H₂₀BrNO₂

7'-(Trifluoromethyl)-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] chemical structure, C12H12F3N, CAS 1203683-05-9

7'-(Trifluoromethyl)-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]

CAS 1203683-05-9C₁₂H₁₂F₃N

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-5'-carbonitrile hydrochloride chemical structure, C12H13ClN2, CAS 1203685-03-3

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-5'-carbonitrile hydrochloride

CAS 1203685-03-3C₁₂H₁₃ClN₂

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-6'-carbonitrile hydrochloride chemical structure, C12H13ClN2, CAS 1203682-92-1

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-6'-carbonitrile hydrochloride

CAS 1203682-92-1C₁₂H₁₃ClN₂

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-6'-carbonitrile chemical structure, C12H12N2, CAS 1203686-68-3

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-6'-carbonitrile

CAS 1203686-68-3C₁₂H₁₂N₂

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-7'-carbonitrile chemical structure, C12H12N2, CAS 1203686-91-2

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-7'-carbonitrile

CAS 1203686-91-2C₁₂H₁₂N₂

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-8'-carbonitrile hydrochloride chemical structure, C12H13ClN2, CAS 1203683-22-0

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-8'-carbonitrile hydrochloride

CAS 1203683-22-0C₁₂H₁₃ClN₂

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-8'-carbonitrile chemical structure, C12H12N2, CAS 1203686-35-4

2',3'-Dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-8'-carbonitrile

CAS 1203686-35-4C₁₂H₁₂N₂