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Murcko scaffold

Ring system with 3 rings and 12 atoms

46 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
12
Chemicals
46
With full pages
3
Scaffold SMILES

c1ccc2c(c1)OCCC21CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(c1)OCCC21CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 46 of 46 chemicals

2,3-Dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-carboxylic acid chemical structure, C12H12O3, CAS 1247429-55-5
2,3-Dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-carboxylic acid
CAS 1247429-55-5C12H12O3
2,3-Dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-amine hydrochloride chemical structure, C11H14ClNO, CAS 1354958-26-1
2,3-Dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-amine hydrochloride
CAS 1354958-26-1C11H14ClNO
2,3-Dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-amine chemical structure, C11H13NO, CAS 1251368-34-9
2,3-Dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-amine
CAS 1251368-34-9C11H13NO
{2,3-Dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-yl}methanamine chemical structure, C12H15NO, CAS 1479808-72-4
{2,3-Dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-yl}methanamine
CAS 1479808-72-4C12H15NO
Methyl 8-chloro-2,2-dimethylspiro[chroman-4,1'-cyclopropane]-6-carboxylate chemical structure, C15H17ClO3, CAS 1350761-59-9
Methyl 8-chloro-2,2-dimethylspiro[chroman-4,1'-cyclopropane]-6-carboxylate
CAS 1350761-59-9C15H17ClO3
Methyl 2,2-dimethylspiro[chroman-4,1'-cyclopropane]-6-carboxylate chemical structure, C15H18O3, CAS 1350761-55-5
Methyl 2,2-dimethylspiro[chroman-4,1'-cyclopropane]-6-carboxylate
CAS 1350761-55-5C15H18O3
5-(Methoxymethoxy)spiro[chromane-4,1'-cyclopropane] chemical structure, C13H16O3, CAS 1380699-12-6
5-(Methoxymethoxy)spiro[chromane-4,1'-cyclopropane]
CAS 1380699-12-6C13H16O3
8-(1,1-Dimethylethyl)-2,3-dihydrospiro[4H-1-benzopyran-4,1'-cyclopropane] chemical structure, C15H20O, CAS 1402888-64-5
8-(1,1-Dimethylethyl)-2,3-dihydrospiro[4H-1-benzopyran-4,1'-cyclopropane]
CAS 1402888-64-5C15H20O
2,2-Dimethyl-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-2'-carboxylic acid chemical structure, C14H16O3, CAS 1536183-36-4
2,2-Dimethyl-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-2'-carboxylic acid
CAS 1536183-36-4C14H16O3
8-Chloro-2,2-dimethylspiro[chroman-4,1'-cyclopropane]-6-carbaldehyde chemical structure, C14H15ClO2, CAS 1350761-61-3
8-Chloro-2,2-dimethylspiro[chroman-4,1'-cyclopropane]-6-carbaldehyde
CAS 1350761-61-3C14H15ClO2
Spiro[chromane-4,1'-cyclopropan]-5-ol chemical structure, C11H12O2, CAS 1380699-13-7
Spiro[chromane-4,1'-cyclopropan]-5-ol
CAS 1380699-13-7C11H12O2
2,2-Dimethylspiro[chroman-4,1'-cyclopropane]-6-carbaldehyde chemical structure, C14H16O2, CAS 1350761-57-7
2,2-Dimethylspiro[chroman-4,1'-cyclopropane]-6-carbaldehyde
CAS 1350761-57-7C14H16O2
8-Bromo-2,3-dihydro-spiro[4H-1-benzopyran-4,1'-cyclopropane] chemical structure, C11H11BrO, CAS 1403387-60-9
8-Bromo-2,3-dihydro-spiro[4H-1-benzopyran-4,1'-cyclopropane]
CAS 1403387-60-9C11H11BrO
rac-(3'R,4R)-2,3-Dihydrospiro[1-benzopyran-4,1'-cyclopropan]-3'-amine chemical structure, C11H13NO, CAS 2305184-90-9
rac-(3'R,4R)-2,3-Dihydrospiro[1-benzopyran-4,1'-cyclopropan]-3'-amine
CAS 2305184-90-9C11H13NO
rac-(3'R,4S)-2,3-Dihydrospiro(1-benzopyran-4,1'-cyclopropane)-3'-carboxylic acid chemical structure, C12H12O3, CAS 2102608-14-8
rac-(3'R,4S)-2,3-Dihydrospiro(1-benzopyran-4,1'-cyclopropane)-3'-carboxylic acid
CAS 2102608-14-8C12H12O3
Cis-2,3-dihydrospiro1-benzopyran-4,1'-cyclopropane-3'-carboxylic acid chemical structure, C12H12O3, CAS 1807901-36-5
Cis-2,3-dihydrospiro1-benzopyran-4,1'-cyclopropane-3'-carboxylic acid
CAS 1807901-36-5C12H12O3
rac-(2'R,4S)-6-Methoxy-2,3-dihydrospiro(1-benzopyran-4,1'-cyclopropane)-2'-carboxylic acid chemical structure, C13H14O4, CAS 2307736-46-3
rac-(2'R,4S)-6-Methoxy-2,3-dihydrospiro(1-benzopyran-4,1'-cyclopropane)-2'-carboxylic acid
CAS 2307736-46-3C13H14O4
(3'S,4R)-6-Fluoro-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-carboxylic acid chemical structure, C12H11FO3, CAS 1807937-73-0
(3'S,4R)-6-Fluoro-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-carboxylic acid
CAS 1807937-73-0C12H11FO3
rac-(3'R,4S)-6-Fluoro-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-carboxylic acid, trans chemical structure, C12H11FO3, CAS 2059911-08-7
rac-(3'R,4S)-6-Fluoro-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-carboxylic acid, trans
CAS 2059911-08-7C12H11FO3
rac-(2'R,4S)-6,7-Dimethyl-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-2'-carboxylic acid, trans chemical structure, C14H16O3, CAS 2059915-15-8
rac-(2'R,4S)-6,7-Dimethyl-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-2'-carboxylic acid, trans
CAS 2059915-15-8C14H16O3
(2'R,4S)-6,7-Dimethyl-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-2'-carboxylic acid chemical structure, C14H16O3, CAS 1807887-95-1
(2'R,4S)-6,7-Dimethyl-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-2'-carboxylic acid
CAS 1807887-95-1C14H16O3
(3'R,4S)-6-Chloro-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-carboxylic acid chemical structure, C12H11ClO3, CAS 1807940-24-4
(3'R,4S)-6-Chloro-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-carboxylic acid
CAS 1807940-24-4C12H11ClO3
6-Methoxy-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-2'-carboxylic acid chemical structure, C13H14O4, CAS 1780014-73-4
6-Methoxy-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-2'-carboxylic acid
CAS 1780014-73-4C13H14O4
6-Fluorospiro[chroman-4,1'-cyclopropane]-2'-carboxylic acid chemical structure, C12H11FO3, CAS 1785229-57-3
6-Fluorospiro[chroman-4,1'-cyclopropane]-2'-carboxylic acid
CAS 1785229-57-3C12H11FO3