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Murcko scaffold

1-Benzyl-3-(phenylamino)pyrrolidine-2,5-dione scaffold

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
10
With full pages
4
Scaffold SMILES

O=C1CC(Nc2ccccc2)C(=O)N1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzyl-3-(phenylamino)pyrrolidine-2,5-dione page
Murcko scaffold O=C1CC(Nc2ccccc2)C(=O)N1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1-Benzyl-3-(hydroxyanilino)-2,5-pyrrolidinedione chemical structure, C17H16N2O3, CAS 308101-38-4
1-Benzyl-3-(hydroxyanilino)-2,5-pyrrolidinedione
CAS 308101-38-4C17H16N2O3
1-Benzyl-3-[(4-fluorophenyl)amino]pyrrolidine-2,5-dione chemical structure, C17H15FN2O2, CAS 306275-89-8
1-Benzyl-3-[(4-fluorophenyl)amino]pyrrolidine-2,5-dione
CAS 306275-89-8C17H15FN2O2
1-Benzyl-3-(4-methoxyanilino)pyrrolidine-2,5-dione chemical structure, C18H18N2O3, CAS 106058-35-9
1-Benzyl-3-(4-methoxyanilino)pyrrolidine-2,5-dione
CAS 106058-35-9C18H18N2O3
1-Benzyl-3-(phenylamino)pyrrolidine-2,5-dione chemical structure, C17H16N2O2, CAS 27036-51-7
1-Benzyl-3-(phenylamino)pyrrolidine-2,5-dione
CAS 27036-51-7C17H16N2O2
1-Benzyl-3-(p-tolylamino)pyrrolidine-2,5-dione chemical structure, C18H18N2O2, CAS 1009770-02-8
1-Benzyl-3-(p-tolylamino)pyrrolidine-2,5-dione
CAS 1009770-02-8C18H18N2O2
3-((4-Ethoxyphenyl)amino)-1-(1-phenylethyl)pyrrolidine-2,5-dione chemical structure, C20H22N2O3, CAS 106058-47-3
3-((4-Ethoxyphenyl)amino)-1-(1-phenylethyl)pyrrolidine-2,5-dione
CAS 106058-47-3C20H22N2O3
2-[4-({1-[(4-Chlorophenyl)methyl]-2,5-dioxopyrrolidin-3-yl}amino)phenyl]acetic acid chemical structure, C19H17ClN2O4, CAS 1009720-68-6
2-[4-({1-[(4-Chlorophenyl)methyl]-2,5-dioxopyrrolidin-3-yl}amino)phenyl]acetic acid
CAS 1009720-68-6C19H17ClN2O4
3-((4-Methoxyphenyl)amino)-1-(4-methylbenzyl)pyrrolidine-2,5-dione chemical structure, C19H20N2O3, CAS 1008080-67-8
3-((4-Methoxyphenyl)amino)-1-(4-methylbenzyl)pyrrolidine-2,5-dione
CAS 1008080-67-8C19H20N2O3
1-Benzyl-3-((4-(dimethylamino)phenyl)amino)pyrrolidine-2,5-dione chemical structure, C19H21N3O2, CAS 1025396-05-7
1-Benzyl-3-((4-(dimethylamino)phenyl)amino)pyrrolidine-2,5-dione
CAS 1025396-05-7C19H21N3O2
1-Benzyl-3-[(2-hydroxyphenyl)amino]pyrrolidine-2,5-dione chemical structure, C17H16N2O3, CAS 1008433-69-9
1-Benzyl-3-[(2-hydroxyphenyl)amino]pyrrolidine-2,5-dione
CAS 1008433-69-9C17H16N2O3