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Murcko scaffold

Ring system with 3 rings and 19 atoms

20 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 19
Chemicals: 20
With full pages: 6

Scaffold SMILES

c1ccc(OCc2nncn2-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(OCc2nncn2-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

2-[[5-[(2,6-Dimethylphenoxy)methyl]-4-(2,6-dimethylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetic acid chemical structure, C21H23N3O3S, CAS 64013-65-6

2-[[5-[(2,6-Dimethylphenoxy)methyl]-4-(2,6-dimethylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetic acid

CAS 64013-65-6C₂₁H₂₃N₃O₃S

2-((5-(Phenoxymethyl)-4-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid chemical structure, C17H15N3O3S, CAS 131142-09-1

2-((5-(Phenoxymethyl)-4-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid

CAS 131142-09-1C₁₇H₁₅N₃O₃S

3-(Isobutylsulfanyl)-5-[(3-methylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazole chemical structure, C20H23N3OS, CAS 443742-28-7

3-(Isobutylsulfanyl)-5-[(3-methylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazole

CAS 443742-28-7C₂₀H₂₃N₃OS

Propan-2-yl {[4-(4-methylphenyl)-5-(phenoxymethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate chemical structure, C21H23N3O3S, CAS 482654-49-9

Propan-2-yl {[4-(4-methylphenyl)-5-(phenoxymethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate

CAS 482654-49-9C₂₁H₂₃N₃O₃S

2-{5-[(2-Methylphenoxy)methyl]-4-phenyl-1,2,4-triazol-3-ylthio}acetamide chemical structure, C18H18N4O2S, CAS 482646-13-9

2-{5-[(2-Methylphenoxy)methyl]-4-phenyl-1,2,4-triazol-3-ylthio}acetamide

CAS 482646-13-9C₁₈H₁₈N₄O₂S

2-((5-((2-Methylphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid chemical structure, C18H17N3O3S, CAS 131142-10-4

2-((5-((2-Methylphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid

CAS 131142-10-4C₁₈H₁₇N₃O₃S

2-[[5-[(4-Bromophenoxy)methyl]-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C17H15BrN4O2S, CAS 482651-45-6

2-[[5-[(4-Bromophenoxy)methyl]-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide

CAS 482651-45-6C₁₇H₁₅BrN₄O₂S

2-({5-[(2-Methoxyphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide chemical structure, C18H18N4O3S, CAS 412922-99-7

2-({5-[(2-Methoxyphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide

CAS 412922-99-7C₁₈H₁₈N₄O₃S

2-[[4-(2-Ethylphenyl)-5-[(2-methylphenoxy)methyl]-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C20H22N4O2S, CAS 570390-00-0

2-[[4-(2-Ethylphenyl)-5-[(2-methylphenoxy)methyl]-1,2,4-triazol-3-yl]sulfanyl]acetamide

CAS 570390-00-0C₂₀H₂₂N₄O₂S

3-(Methylsulfanyl)-4-phenyl-5-{[3-(trifluoromethyl)phenoxy]methyl}-4H-1,2,4-triazole chemical structure, C17H14F3N3OS, CAS 383145-82-2

3-(Methylsulfanyl)-4-phenyl-5-{[3-(trifluoromethyl)phenoxy]methyl}-4H-1,2,4-triazole

CAS 383145-82-2C₁₇H₁₄F₃N₃OS

2-[(4-Phenyl-5-{[3-(trifluoromethyl)phenoxy]methyl}-4H-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C18H15F3N4O2S, CAS 383145-84-4

2-[(4-Phenyl-5-{[3-(trifluoromethyl)phenoxy]methyl}-4H-1,2,4-triazol-3-yl)sulfanyl]acetamide

CAS 383145-84-4C₁₈H₁₅F₃N₄O₂S

2-({5-[(2,6-Dimethylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)-N-(2-methylpropyl)acetamide chemical structure, C23H28N4O2S, CAS 941133-80-8

2-({5-[(2,6-Dimethylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)-N-(2-methylpropyl)acetamide

CAS 941133-80-8C₂₃H₂₈N₄O₂S

2-((5-((4-Chlorophenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C17H15ClN4O2S, CAS 332911-17-8

2-((5-((4-Chlorophenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide

CAS 332911-17-8C₁₇H₁₅ClN₄O₂S

2-((5-((2,6-Dimethylphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid chemical structure, C19H19N3O3S, CAS 64013-61-2

2-((5-((2,6-Dimethylphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid

CAS 64013-61-2C₁₉H₁₉N₃O₃S

(Z)-2-[4-(4-Chlorophenyl)-5-[[3-(trifluoromethyl)phenoxy]methyl]-1,2,4-triazol-3-yl]-N,N-dimethyl-2-nitroethenamine chemical structure, C20H17ClF3N5O3, CAS 400078-60-6

(Z)-2-[4-(4-Chlorophenyl)-5-[[3-(trifluoromethyl)phenoxy]methyl]-1,2,4-triazol-3-yl]-N,N-dimethyl-2-nitroethenamine

CAS 400078-60-6C₂₀H₁₇ClF₃N₅O₃

3-[(4-Chlorophenoxy)methyl]-5-(methylsulfanyl)-4-phenyl-4H-1,2,4-triazole chemical structure, C16H14ClN3OS, CAS 116454-44-5

3-[(4-Chlorophenoxy)methyl]-5-(methylsulfanyl)-4-phenyl-4H-1,2,4-triazole

CAS 116454-44-5C₁₆H₁₄ClN₃OS

2-{[4-(4-Ethoxyphenyl)-5-(phenoxymethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid chemical structure, C19H19N3O4S, CAS 893725-77-4

2-{[4-(4-Ethoxyphenyl)-5-(phenoxymethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid

CAS 893725-77-4C₁₉H₁₉N₃O₄S

2-((4-(4-Bromophenyl)-5-(phenoxymethyl)-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid chemical structure, C17H14BrN3O3S, CAS 893725-81-0

2-((4-(4-Bromophenyl)-5-(phenoxymethyl)-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid

CAS 893725-81-0C₁₇H₁₄BrN₃O₃S

2-((4-(4-Methoxyphenyl)-5-(phenoxymethyl)-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid chemical structure, C18H17N3O4S, CAS 893725-85-4

2-((4-(4-Methoxyphenyl)-5-(phenoxymethyl)-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid

CAS 893725-85-4C₁₈H₁₇N₃O₄S

2-{[5-(1-Phenoxyethyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C18H18N4O2S, CAS 950233-55-3

2-{[5-(1-Phenoxyethyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 950233-55-3C₁₈H₁₈N₄O₂S