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Murcko scaffold

1-Oxaspiro[4.5]decan-2-one scaffold

35 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
35
With full pages
2
Scaffold SMILES

O=C1CCC2(CCCCC2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Oxaspiro[4.5]decan-2-one page
Murcko scaffold O=C1CCC2(CCCCC2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

1-Oxaspiro[4.5]decan-2-one chemical structure, C9H14O2, CAS 699-61-6
1-Oxaspiro[4.5]decan-2-one
CAS 699-61-6C9H14O2
2-Oxo-1-oxaspiro(4.5)decane-4-carboxylic acid chemical structure, C10H14O4, CAS 2819-56-9
2-Oxo-1-oxaspiro(4.5)decane-4-carboxylic acid
CAS 2819-56-9C10H14O4
1-Oxaspiro(4.5)decane-4-carboxylic acid, 2-oxo-, methyl ester chemical structure, C11H16O4, CAS 2819-57-0
1-Oxaspiro(4.5)decane-4-carboxylic acid, 2-oxo-, methyl ester
CAS 2819-57-0C11H16O4
1-Oxaspiro(4.5)decan-2-one, 8-methyl- chemical structure, C10H16O2, CAS 94201-19-1
1-Oxaspiro(4.5)decan-2-one, 8-methyl-
CAS 94201-19-1C10H16O2
3-(Trifluoromethyl)-1-oxaspiro[4.5]decan-2-one chemical structure, C10H13F3O2, CAS 236736-26-8
3-(Trifluoromethyl)-1-oxaspiro[4.5]decan-2-one
CAS 236736-26-8C10H13F3O2
2-Oxo-1-oxa-spiro[4.5]decane-3,4-dicarboxylic acid diethyl ester chemical structure, C15H22O6, CAS 134515-27-8
2-Oxo-1-oxa-spiro[4.5]decane-3,4-dicarboxylic acid diethyl ester
CAS 134515-27-8C15H22O6
2-Oxo-1-oxa-spiro[4.5]decane-4-carboxylic acid ethyl ester chemical structure, C12H18O4, CAS 61858-03-5
2-Oxo-1-oxa-spiro[4.5]decane-4-carboxylic acid ethyl ester
CAS 61858-03-5C12H18O4
1-Oxaspiro(4.5)decane-4-carboxamide, N,N-diethyl-2-oxo- chemical structure, C14H23NO3, CAS 136547-40-5
1-Oxaspiro(4.5)decane-4-carboxamide, N,N-diethyl-2-oxo-
CAS 136547-40-5C14H23NO3
N-(sec-Butyl)-2-oxo-1-oxaspiro[4.5]decane-4-carboxamide chemical structure, C14H23NO3, CAS 433966-81-5
N-(sec-Butyl)-2-oxo-1-oxaspiro[4.5]decane-4-carboxamide
CAS 433966-81-5C14H23NO3
1-Oxaspiro(4.5)decane-4-carboxamide, 2-oxo- chemical structure, C10H15NO3, CAS 136547-37-0
1-Oxaspiro(4.5)decane-4-carboxamide, 2-oxo-
CAS 136547-37-0C10H15NO3
1-Oxaspiro(4.5)decane-4-carboxamide, N,N-dimethyl-2-oxo- chemical structure, C12H19NO3, CAS 136547-39-2
1-Oxaspiro(4.5)decane-4-carboxamide, N,N-dimethyl-2-oxo-
CAS 136547-39-2C12H19NO3
N-Isopentyl-2-oxo-1-oxaspiro[4.5]decane-4-carboxamide chemical structure, C15H25NO3, CAS 440109-76-2
N-Isopentyl-2-oxo-1-oxaspiro[4.5]decane-4-carboxamide
CAS 440109-76-2C15H25NO3
2-Oxo-N-pentyl-1-oxaspiro[4.5]decane-4-carboxamide chemical structure, C15H25NO3, CAS 440109-78-4
2-Oxo-N-pentyl-1-oxaspiro[4.5]decane-4-carboxamide
CAS 440109-78-4C15H25NO3
1-Oxaspiro[4.5]decan-2-one, 4-(chloroacetyl)-(9CI) chemical structure, C11H15ClO3, CAS 137180-64-4
1-Oxaspiro[4.5]decan-2-one, 4-(chloroacetyl)-(9CI)
CAS 137180-64-4C11H15ClO3
8-(1,1-Dimethylethyl)-1-oxaspiro[4.5]decan-2-one chemical structure, C13H22O2, CAS 72258-83-4
8-(1,1-Dimethylethyl)-1-oxaspiro[4.5]decan-2-one
CAS 72258-83-4C13H22O2
1-Oxaspiro[4.5]decane-4-carbothioamide, 2-oxo- chemical structure, C10H15NO2S, CAS 137180-69-9
1-Oxaspiro[4.5]decane-4-carbothioamide, 2-oxo-
CAS 137180-69-9C10H15NO2S
1-Oxaspiro(4.5)decan-2-one, 8-(1-methylethyl)-, trans- chemical structure, C12H20O2, CAS 4625-90-5
1-Oxaspiro(4.5)decan-2-one, 8-(1-methylethyl)-, trans-
CAS 4625-90-5C12H20O2
Methyl 3-methyl-2-oxo-1-oxaspiro[4.5]decane-4-carboxylate chemical structure, C12H18O4, CAS 16149-81-8
Methyl 3-methyl-2-oxo-1-oxaspiro[4.5]decane-4-carboxylate
CAS 16149-81-8C12H18O4
3-Hydroxy-1-oxaspiro[4.5]decan-2-one chemical structure, C9H14O3, CAS 274913-93-8
3-Hydroxy-1-oxaspiro[4.5]decan-2-one
CAS 274913-93-8C9H14O3
1-Oxaspiro(4.5)decan-2-one, 8-ethyl-, cis- chemical structure, C11H18O2, CAS 91069-39-5
1-Oxaspiro(4.5)decan-2-one, 8-ethyl-, cis-
CAS 91069-39-5C11H18O2
8-(1,1-Dimethylethyl)-4-methoxy-1-oxaspiro[4.5]decan-2-one chemical structure, C14H24O3, CAS 63413-92-3
8-(1,1-Dimethylethyl)-4-methoxy-1-oxaspiro[4.5]decan-2-one
CAS 63413-92-3C14H24O3
1-Oxaspiro(4.5)decane-4-carboxylic acid, 2-oxo-, sodium salt chemical structure, C10H13NaO4, CAS 51706-66-2
1-Oxaspiro(4.5)decane-4-carboxylic acid, 2-oxo-, sodium salt
CAS 51706-66-2C10H13NaO4
1-Oxaspiro(4.5)decane-4-carboxylic acid, 3-methyl-2-oxo-, sodium salt chemical structure, C11H15NaO4, CAS 52417-17-1
1-Oxaspiro(4.5)decane-4-carboxylic acid, 3-methyl-2-oxo-, sodium salt
CAS 52417-17-1C11H15NaO4
3,6-Dimethyl-1-oxaspiro(4.5)decan-2-one chemical structure, C11H18O2, CAS 93840-81-4
3,6-Dimethyl-1-oxaspiro(4.5)decan-2-one
CAS 93840-81-4C11H18O2