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Murcko scaffold

Ring system with 3 rings and 18 atoms

17 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 18
Chemicals: 17
With full pages: 4

Scaffold SMILES

c1ccc(COc2cnc3ccccc3c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(COc2cnc3ccccc3c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

3-[(4-Chlorophenyl)methoxy]-2-methylquinoline chemical structure, C17H14ClNO, CAS 861206-10-2

3-[(4-Chlorophenyl)methoxy]-2-methylquinoline

CAS 861206-10-2C₁₇H₁₄ClNO

6,8-Dibromo-3-[(4-chlorophenyl)methoxy]-2-methylquinoline chemical structure, C17H12Br2ClNO, CAS 861210-57-3

6,8-Dibromo-3-[(4-chlorophenyl)methoxy]-2-methylquinoline

CAS 861210-57-3C₁₇H₁₂Br₂ClNO

3-[(4-Fluorophenyl)methoxy]-2-methylquinoline chemical structure, C17H14FNO, CAS 861206-47-5

3-[(4-Fluorophenyl)methoxy]-2-methylquinoline

CAS 861206-47-5C₁₇H₁₄FNO

3-[(3-Methoxyphenyl)methoxy]-2-methylquinoline chemical structure, C18H17NO2, CAS 861206-46-4

3-[(3-Methoxyphenyl)methoxy]-2-methylquinoline

CAS 861206-46-4C₁₈H₁₇NO₂

3-(Benzyloxy)-2-methylquinoline chemical structure, C17H15NO, CAS 5264-03-9

3-(Benzyloxy)-2-methylquinoline

CAS 5264-03-9C₁₇H₁₅NO

3-(Benzyloxy)quinoline-2-carboxylic acid chemical structure, C17H13NO3, CAS 110429-24-8

3-(Benzyloxy)quinoline-2-carboxylic acid

CAS 110429-24-8C₁₇H₁₃NO₃

3-(Benzyloxy)quinoline-2-carbaldehyde chemical structure, C17H13NO2, CAS 110429-25-9

3-(Benzyloxy)quinoline-2-carbaldehyde

CAS 110429-25-9C₁₇H₁₃NO₂

3-(Benzyloxy)-8-nitroquinoline chemical structure, C16H12N2O3, CAS 1201437-19-5

3-(Benzyloxy)-8-nitroquinoline

CAS 1201437-19-5C₁₆H₁₂N₂O₃

1,3-Diethyl 2-[[[3-(phenylmethoxy)-8-quinolinyl]amino]methylene]propanedioate chemical structure, C24H24N2O5, CAS 887407-40-1

1,3-Diethyl 2-[[[3-(phenylmethoxy)-8-quinolinyl]amino]methylene]propanedioate

CAS 887407-40-1C₂₄H₂₄N₂O₅

3-(Benzyloxy)-8-bromo-6-chloroquinoline chemical structure, C16H11BrClNO, CAS 2173070-84-1

3-(Benzyloxy)-8-bromo-6-chloroquinoline

CAS 2173070-84-1C₁₆H₁₁BrClNO

3-(Benzyloxy)-8-bromo-6-methylquinoline chemical structure, C17H14BrNO, CAS 2173070-87-4

3-(Benzyloxy)-8-bromo-6-methylquinoline

CAS 2173070-87-4C₁₇H₁₄BrNO

7-Chloro-6-fluoro-3-((4-methoxybenzyl)oxy)quinolin-2-amine chemical structure, C17H14ClFN2O2, CAS 2435612-29-4

7-Chloro-6-fluoro-3-((4-methoxybenzyl)oxy)quinolin-2-amine

CAS 2435612-29-4C₁₇H₁₄ClFN₂O₂

6-Fluoro-3-((4-methoxybenzyl)oxy)quinolin-2-amine chemical structure, C17H15FN2O2, CAS 2435612-27-2

6-Fluoro-3-((4-methoxybenzyl)oxy)quinolin-2-amine

CAS 2435612-27-2C₁₇H₁₅FN₂O₂

Methyl 2-amino-3-((4-methoxybenzyl)oxy)quinoline-6-carboxylate chemical structure, C19H18N2O4, CAS 2435612-38-5

Methyl 2-amino-3-((4-methoxybenzyl)oxy)quinoline-6-carboxylate

CAS 2435612-38-5C₁₉H₁₈N₂O₄

6,8-Difluoro-3-((4-methoxybenzyl)oxy)quinolin-2-amine chemical structure, C17H14F2N2O2, CAS 2435612-30-7

6,8-Difluoro-3-((4-methoxybenzyl)oxy)quinolin-2-amine

CAS 2435612-30-7C₁₇H₁₄F₂N₂O₂

tert-Butyl 2-(3-(benzyloxy)quinolin-6-yl)-2,2-difluoroacetate chemical structure, C22H21F2NO3, CAS 1310419-10-3

tert-Butyl 2-(3-(benzyloxy)quinolin-6-yl)-2,2-difluoroacetate

CAS 1310419-10-3C₂₂H₂₁F₂NO₃

3-Benzyloxyquinolin-8-ol chemical structure, C16H13NO2, CAS 1140520-27-9

3-Benzyloxyquinolin-8-ol

CAS 1140520-27-9C₁₆H₁₃NO₂