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Murcko scaffold

Ring system with 3 rings and 16 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
15
With full pages
5
Scaffold SMILES

O=C1CSC2=NCN(c3ccccc3)CN12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CSC2=NCN(c3ccccc3)CN12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

3-(4-Ethoxyphenyl)-3,4-dihydro-2H-[1,3]thiazolo[3,2-a][1,3,5]triazin-6(7H)-one chemical structure, C13H15N3O2S, CAS 361986-21-2
3-(4-Ethoxyphenyl)-3,4-dihydro-2H-[1,3]thiazolo[3,2-a][1,3,5]triazin-6(7H)-one
CAS 361986-21-2C13H15N3O2S
7,7-Bis(hydroxymethyl)-3-(4-methoxyphenyl)-3,4-dihydro-2H-[1,3]thiazolo[3,2-a][1,3,5]triazin-6(7H)-one chemical structure, C14H17N3O4S, CAS 303207-14-9
7,7-Bis(hydroxymethyl)-3-(4-methoxyphenyl)-3,4-dihydro-2H-[1,3]thiazolo[3,2-a][1,3,5]triazin-6(7H)-one
CAS 303207-14-9C14H17N3O4S
3-(3-Chlorophenyl)-3,4-dihydro-2H-[1,3]thiazolo[3,2-a][1,3,5]triazin-6(7H)-one chemical structure, C11H10ClN3OS, CAS 78153-33-0
3-(3-Chlorophenyl)-3,4-dihydro-2H-[1,3]thiazolo[3,2-a][1,3,5]triazin-6(7H)-one
CAS 78153-33-0C11H10ClN3OS
3-(4-Acetylphenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C13H13N3O2S, CAS 378213-41-3
3-(4-Acetylphenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 378213-41-3C13H13N3O2S
3-(3,5-Dimethylphenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C13H15N3OS, CAS 672886-30-5
3-(3,5-Dimethylphenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 672886-30-5C13H15N3OS
3-(4-Bromophenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C11H10BrN3OS, CAS 510721-24-1
3-(4-Bromophenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 510721-24-1C11H10BrN3OS
3-(4-Fluorophenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C11H10FN3OS, CAS 306735-78-4
3-(4-Fluorophenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 306735-78-4C11H10FN3OS
3-(3,4-Dimethylphenyl)-3,4-dihydro-2H-[1,3]thiazolo[3,2-a][1,3,5]triazin-6(7H)-one chemical structure, C13H15N3OS, CAS 326012-50-4
3-(3,4-Dimethylphenyl)-3,4-dihydro-2H-[1,3]thiazolo[3,2-a][1,3,5]triazin-6(7H)-one
CAS 326012-50-4C13H15N3OS
3-(4-Iodophenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C11H10IN3OS, CAS 326610-05-3
3-(4-Iodophenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 326610-05-3C11H10IN3OS
3-(3-Chloro-4-methylphenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C12H12ClN3OS, CAS 672894-71-2
3-(3-Chloro-4-methylphenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 672894-71-2C12H12ClN3OS
3-(4-Methoxyphenyl)-2,4-dihydrothiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C12H13N3O2S, CAS 78153-35-2
3-(4-Methoxyphenyl)-2,4-dihydrothiazolo[3,2-a][1,3,5]triazin-6-one
CAS 78153-35-2C12H13N3O2S
3-(3-Nitrophenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C11H10N4O3S, CAS 78659-62-8
3-(3-Nitrophenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 78659-62-8C11H10N4O3S
Ethyl 4-(6-oxo-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-3-yl)benzoate chemical structure, C14H15N3O3S, CAS 381196-19-6
Ethyl 4-(6-oxo-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-3-yl)benzoate
CAS 381196-19-6C14H15N3O3S
3-(4-Nitrophenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C11H10N4O3S, CAS 361986-32-5
3-(4-Nitrophenyl)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 361986-32-5C11H10N4O3S
2H-Thiazolo[3,2-a]-1,3,5-triazin-6(7H)-one, 3-(3-bromophenyl)-3,4-dihydro- chemical structure, C11H10BrN3OS, CAS 78153-34-1
2H-Thiazolo[3,2-a]-1,3,5-triazin-6(7H)-one, 3-(3-bromophenyl)-3,4-dihydro-
CAS 78153-34-1C11H10BrN3OS