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Murcko scaffold

Ring system with 3 rings and 21 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
8
With full pages
5
Scaffold SMILES

O=C1CCc2cc(S(=O)(=O)Nc3ccccc3)ccc2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCc2cc(S(=O)(=O)Nc3ccccc3)ccc2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-(4-Methylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide chemical structure, C16H16N2O3S, CAS 878949-29-2
N-(4-Methylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide
CAS 878949-29-2C16H16N2O3S
N-(3,4-Dimethylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide chemical structure, C17H18N2O3S, CAS 899717-26-1
N-(3,4-Dimethylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide
CAS 899717-26-1C17H18N2O3S
N-(3-Fluoro-2-methylphenyl)-2-oxo-1,2,3,4-tetrahydroquinoline-6-sulfonamide chemical structure, C16H15FN2O3S, CAS 893778-64-8
N-(3-Fluoro-2-methylphenyl)-2-oxo-1,2,3,4-tetrahydroquinoline-6-sulfonamide
CAS 893778-64-8C16H15FN2O3S
N-(4-Acetylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide chemical structure, C17H16N2O4S, CAS 878949-48-5
N-(4-Acetylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide
CAS 878949-48-5C17H16N2O4S
N-(2-Fluorophenyl)-2-oxo-1,2,3,4-tetrahydroquinoline-6-sulfonamide chemical structure, C15H13FN2O3S, CAS 879178-93-5
N-(2-Fluorophenyl)-2-oxo-1,2,3,4-tetrahydroquinoline-6-sulfonamide
CAS 879178-93-5C15H13FN2O3S
N-(4-Fluorophenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide chemical structure, C15H13FN2O3S, CAS 879178-88-8
N-(4-Fluorophenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide
CAS 879178-88-8C15H13FN2O3S
N-(3,4-Dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinoline-6-sulfonamide chemical structure, C15H12Cl2N2O3S, CAS 1030222-01-5
N-(3,4-Dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinoline-6-sulfonamide
CAS 1030222-01-5C15H12Cl2N2O3S
PKM2 activator 3 chemical structure, C15H11ClF2N2O3S, CAS 1346113-84-5
PKM2 activator 3
CAS 1346113-84-5C15H11ClF2N2O3S