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Murcko scaffold

Ring system with 3 rings and 18 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
13
With full pages
3
Scaffold SMILES

c1ccc(Sc2cnn(-c3ccccc3)c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Sc2cnn(-c3ccccc3)c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

3,5-Dimethyl-4-[(4-nitrophenyl)sulfanyl]-1-phenyl-1H-pyrazole chemical structure, C17H15N3O2S, CAS 245725-86-4
3,5-Dimethyl-4-[(4-nitrophenyl)sulfanyl]-1-phenyl-1H-pyrazole
CAS 245725-86-4C17H15N3O2S
3,5-Dimethyl-1-phenyl-4-(phenylthio)-1H-pyrazole chemical structure, C17H16N2S, CAS 245725-85-3
3,5-Dimethyl-1-phenyl-4-(phenylthio)-1H-pyrazole
CAS 245725-85-3C17H16N2S
5-Methoxy-3-methyl-4-[(4-nitrophenyl)sulfanyl]-1-phenyl-1H-pyrazole chemical structure, C17H15N3O3S, CAS 245725-82-0
5-Methoxy-3-methyl-4-[(4-nitrophenyl)sulfanyl]-1-phenyl-1H-pyrazole
CAS 245725-82-0C17H15N3O3S
3,5-Dimethyl-4-((2-nitrophenyl)thio)-1-phenyl-1H-pyrazole chemical structure, C17H15N3O2S, CAS 93332-34-4
3,5-Dimethyl-4-((2-nitrophenyl)thio)-1-phenyl-1H-pyrazole
CAS 93332-34-4C17H15N3O2S
Methyl 2-({3-methyl-4-[(4-nitrophenyl)sulfanyl]-1-phenyl-1H-pyrazol-5-yl}oxy)acetate chemical structure, C19H17N3O5S, CAS 956158-96-6
Methyl 2-({3-methyl-4-[(4-nitrophenyl)sulfanyl]-1-phenyl-1H-pyrazol-5-yl}oxy)acetate
CAS 956158-96-6C19H17N3O5S
4-((4-Bromophenyl)thio)-3,5-dimethyl-1-phenyl-1H-pyrazole chemical structure, C17H15BrN2S, CAS 394236-62-5
4-((4-Bromophenyl)thio)-3,5-dimethyl-1-phenyl-1H-pyrazole
CAS 394236-62-5C17H15BrN2S
4-((4-Chlorophenyl)thio)-3-methyl-1-phenyl-1H-pyrazol-5-yl isobutyrate chemical structure, C20H19ClN2O2S, CAS 851126-53-9
4-((4-Chlorophenyl)thio)-3-methyl-1-phenyl-1H-pyrazol-5-yl isobutyrate
CAS 851126-53-9C20H19ClN2O2S
[4-(4-Chlorophenyl)sulfanyl-5-methyl-2-phenylpyrazol-3-yl] butanoate chemical structure, C20H19ClN2O2S, CAS 851126-54-0
[4-(4-Chlorophenyl)sulfanyl-5-methyl-2-phenylpyrazol-3-yl] butanoate
CAS 851126-54-0C20H19ClN2O2S
3-Methyl-1-phenyl-4-(p-tolylthio)-1H-pyrazol-5-yl 2-methoxyacetate chemical structure, C20H20N2O3S, CAS 851126-62-0
3-Methyl-1-phenyl-4-(p-tolylthio)-1H-pyrazol-5-yl 2-methoxyacetate
CAS 851126-62-0C20H20N2O3S
3-Methyl-1-phenyl-4-(p-tolylthio)-1H-pyrazol-5-yl pivalate chemical structure, C22H24N2O2S, CAS 851126-66-4
3-Methyl-1-phenyl-4-(p-tolylthio)-1H-pyrazol-5-yl pivalate
CAS 851126-66-4C22H24N2O2S
5-Methyl-4-(4-nitrophenyl)sulfanyl-2-phenylpyrazol-3-amine chemical structure, C16H14N4O2S, CAS 32527-84-7
5-Methyl-4-(4-nitrophenyl)sulfanyl-2-phenylpyrazol-3-amine
CAS 32527-84-7C16H14N4O2S
4-[(3-Chlorophenyl)thio]-3-methyl-1-(4-nitrophenyl)-1H-pyrazole chemical structure, C16H12ClN3O2S, CAS 2197053-48-6
4-[(3-Chlorophenyl)thio]-3-methyl-1-(4-nitrophenyl)-1H-pyrazole
CAS 2197053-48-6C16H12ClN3O2S
Orb3210333 chemical structure, C16H14ClN3S, CAS 2743456-25-7
Orb3210333
CAS 2743456-25-7C16H14ClN3S