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Murcko scaffold

6-(Piperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine scaffold

30 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
30
With full pages
3
Scaffold SMILES

c1cc2nncn2nc1N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-(Piperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine page
Murcko scaffold c1cc2nncn2nc1N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

3-Chloro-6-(4-methylpiperazin-1-yl)[1,2,4]triazolo[4,3-b]pyridazine chemical structure, C10H13ClN6, CAS 52494-60-7
3-Chloro-6-(4-methylpiperazin-1-yl)[1,2,4]triazolo[4,3-b]pyridazine
CAS 52494-60-7C10H13ClN6
Piperazine-1-carboxylic acid, 4-(3-trifluoromethyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-, ethyl ester chemical structure, C13H15F3N6O2, CAS 300689-09-2
Piperazine-1-carboxylic acid, 4-(3-trifluoromethyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-, ethyl ester
CAS 300689-09-2C13H15F3N6O2
3-Methyl-6-(4-methylpiperazin-1-yl)[1,2,4]triazolo[4,3-b]pyridazine chemical structure, C11H16N6, CAS 300586-17-8
3-Methyl-6-(4-methylpiperazin-1-yl)[1,2,4]triazolo[4,3-b]pyridazine
CAS 300586-17-8C11H16N6
1-{3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine chemical structure, C10H14N6, CAS 300588-79-8
1-{3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine
CAS 300588-79-8C10H14N6
6-(4-Methylpiperazin-1-yl)-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine chemical structure, C11H13F3N6, CAS 338748-53-1
6-(4-Methylpiperazin-1-yl)-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine
CAS 338748-53-1C11H13F3N6
6-Piperazino-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine chemical structure, C10H11F3N6, CAS 338748-56-4
6-Piperazino-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine
CAS 338748-56-4C10H11F3N6
1-Methanesulfonyl-4-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperazine chemical structure, C11H13F3N6O2S, CAS 930987-75-0
1-Methanesulfonyl-4-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperazine
CAS 930987-75-0C11H13F3N6O2S
1-{4-[3-(Trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperazin-1-yl}ethanone chemical structure, C12H13F3N6O, CAS 930856-78-3
1-{4-[3-(Trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperazin-1-yl}ethanone
CAS 930856-78-3C12H13F3N6O
6-(4-Ethylpiperazin-1-yl)-3-methyl[1,2,4]triazolo[4,3-b]pyridazine chemical structure, C12H18N6, CAS 931727-40-1
6-(4-Ethylpiperazin-1-yl)-3-methyl[1,2,4]triazolo[4,3-b]pyridazine
CAS 931727-40-1C12H18N6
6-(4-Ethylpiperazin-1-yl)-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine chemical structure, C12H15F3N6, CAS 1010623-73-0
6-(4-Ethylpiperazin-1-yl)-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine
CAS 1010623-73-0C12H15F3N6
1-(Ethanesulfonyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine chemical structure, C12H18N6O2S, CAS 1060224-04-5
1-(Ethanesulfonyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine
CAS 1060224-04-5C12H18N6O2S
1-{3-Ethyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-4-(propane-1-sulfonyl)piperazine chemical structure, C14H22N6O2S, CAS 1021225-71-7
1-{3-Ethyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-4-(propane-1-sulfonyl)piperazine
CAS 1021225-71-7C14H22N6O2S
Ethyl 4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperazine-1-carboxylate chemical structure, C12H16N6O2, CAS 931943-55-4
Ethyl 4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperazine-1-carboxylate
CAS 931943-55-4C12H16N6O2
6-(4-Ethylpiperazin-1-yl)[1,2,4]triazolo[4,3-b]pyridazine chemical structure, C11H16N6, CAS 931943-59-8
6-(4-Ethylpiperazin-1-yl)[1,2,4]triazolo[4,3-b]pyridazine
CAS 931943-59-8C11H16N6
1-(Prop-2-yn-1-yl)-4-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperazine chemical structure, C13H13F3N6, CAS 1197779-45-5
1-(Prop-2-yn-1-yl)-4-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperazine
CAS 1197779-45-5C13H13F3N6
6-(4-Methylpiperazino)-1,2,4-triazolo[4,3-b]pyridazine chemical structure, C10H14N6, CAS 243444-80-6
6-(4-Methylpiperazino)-1,2,4-triazolo[4,3-b]pyridazine
CAS 243444-80-6C10H14N6
6-(4-Ethylpiperazino)-3-isopropyl[1,2,4]triazolo[4,3-b]pyridazine chemical structure, C14H22N6, CAS 1144434-22-9
6-(4-Ethylpiperazino)-3-isopropyl[1,2,4]triazolo[4,3-b]pyridazine
CAS 1144434-22-9C14H22N6
3-Ethyl-6-(4-ethylpiperazino)[1,2,4]triazolo[4,3-b]pyridazine chemical structure, C13H20N6, CAS 1144445-34-0
3-Ethyl-6-(4-ethylpiperazino)[1,2,4]triazolo[4,3-b]pyridazine
CAS 1144445-34-0C13H20N6
1-(4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)piperazin-1-yl)ethanone chemical structure, C11H14N6O, CAS 1144483-83-9
1-(4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)piperazin-1-yl)ethanone
CAS 1144483-83-9C11H14N6O
6-(Piperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine chemical structure, C9H12N6, CAS 1204296-27-4
6-(Piperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine
CAS 1204296-27-4C9H12N6
3-Ethyl-6-piperazin-1-yl[1,2,4]triazolo[4,3-b]pyridazine chemical structure, C11H16N6, CAS 1204296-47-8
3-Ethyl-6-piperazin-1-yl[1,2,4]triazolo[4,3-b]pyridazine
CAS 1204296-47-8C11H16N6
tert-Butyl 4-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperazine-1-carboxylate chemical structure, C15H19F3N6O2, CAS 1166819-50-6
tert-Butyl 4-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperazine-1-carboxylate
CAS 1166819-50-6C15H19F3N6O2
tert-Butyl 4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperazine-1-carboxylate chemical structure, C15H22N6O2, CAS 1313823-83-4
tert-Butyl 4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperazine-1-carboxylate
CAS 1313823-83-4C15H22N6O2
2-Methyl-1-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine chemical structure, C10H14N6, CAS 1306605-92-4
2-Methyl-1-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine
CAS 1306605-92-4C10H14N6