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Murcko scaffold

Ring system with 2 rings and 17 atoms

13 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
13
With full pages
3
Scaffold SMILES

C=C(N=Nc1ccccc1)C(=O)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C=C(N=Nc1ccccc1)C(=O)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

Propane-1,2,3-trione, 1-(2-thienyl)-, 2-(4-methoxyphenyl)hydrazone chemical structure, C14H12N2O3S, CAS 338400-20-7
Propane-1,2,3-trione, 1-(2-thienyl)-, 2-(4-methoxyphenyl)hydrazone
CAS 338400-20-7C14H12N2O3S
2-[2-(3-Methylphenyl)hydrazono]-3-oxo-3-(2-thienyl)propanal chemical structure, C14H12N2O2S, CAS 338400-27-4
2-[2-(3-Methylphenyl)hydrazono]-3-oxo-3-(2-thienyl)propanal
CAS 338400-27-4C14H12N2O2S
3-Oxo-2-(2-phenylhydrazono)-3-(2-thienyl)propanal chemical structure, C13H10N2O2S, CAS 337512-14-8
3-Oxo-2-(2-phenylhydrazono)-3-(2-thienyl)propanal
CAS 337512-14-8C13H10N2O2S
(2E)-3-Oxo-2-(2-phenylhydrazin-1-ylidene)-3-(thiophen-2-yl)propanal chemical structure, C13H10N2O2S
(2E)-3-Oxo-2-(2-phenylhydrazin-1-ylidene)-3-(thiophen-2-yl)propanal
C13H10N2O2S
(Z)-2-[(4-Chlorophenyl)diazenyl]-3-hydroxy-1-thiophen-2-ylprop-2-en-1-one chemical structure, C13H9ClN2O2S
(Z)-2-[(4-Chlorophenyl)diazenyl]-3-hydroxy-1-thiophen-2-ylprop-2-en-1-one
C13H9ClN2O2S
(2E)-2-[(4-Methoxyphenyl)hydrazono]-3-oxo-3-(2-thienyl)propanal chemical structure, C14H12N2O3S
(2E)-2-[(4-Methoxyphenyl)hydrazono]-3-oxo-3-(2-thienyl)propanal
C14H12N2O3S
Ethyl 2,4-dioxo-4-(2-thienyl)-3-{2-[2-(trifluoromethyl)phenyl]hydrazono}butanoate chemical structure, C17H13F3N2O4S, CAS 265307-60-6
Ethyl 2,4-dioxo-4-(2-thienyl)-3-{2-[2-(trifluoromethyl)phenyl]hydrazono}butanoate
CAS 265307-60-6C17H13F3N2O4S
(2E)-2-[2-(4-Chlorophenyl)hydrazin-1-ylidene]-3-oxo-3-(thiophen-2-yl)propanal chemical structure, C13H9ClN2O2S, CAS 338400-26-3
(2E)-2-[2-(4-Chlorophenyl)hydrazin-1-ylidene]-3-oxo-3-(thiophen-2-yl)propanal
CAS 338400-26-3C13H9ClN2O2S
(2Z)-2-[2-(3-Methylphenyl)hydrazin-1-ylidene]-3-oxo-3-(thiophen-2-yl)propanal chemical structure, C14H12N2O2S
(2Z)-2-[2-(3-Methylphenyl)hydrazin-1-ylidene]-3-oxo-3-(thiophen-2-yl)propanal
C14H12N2O2S
(2E)-3-Oxo-2-(2-phenylhydrazin-1-ylidene)-3-(thiophen-2-yl)propanal chemical structure, C13H10N2O2S
(2E)-3-Oxo-2-(2-phenylhydrazin-1-ylidene)-3-(thiophen-2-yl)propanal
C13H10N2O2S
2-[2-(4-Methoxyphenyl)hydrazono]-3-oxo-3-(2-thienyl)propanal chemical structure, C14H12N2O3S
2-[2-(4-Methoxyphenyl)hydrazono]-3-oxo-3-(2-thienyl)propanal
C14H12N2O3S
2-[2-(4-Chlorophenyl)hydrazono]-3-oxo-3-(2-thienyl)propanal chemical structure, C13H9ClN2O2S
2-[2-(4-Chlorophenyl)hydrazono]-3-oxo-3-(2-thienyl)propanal
C13H9ClN2O2S
(E)-3-Hydroxy-2-[(3-methylphenyl)diazenyl]-1-thiophen-2-ylprop-2-en-1-one chemical structure, C14H12N2O2S
(E)-3-Hydroxy-2-[(3-methylphenyl)diazenyl]-1-thiophen-2-ylprop-2-en-1-one
C14H12N2O2S