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Murcko scaffold

Ring system with 3 rings and 23 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
8
With full pages
3
Scaffold SMILES

O=S(=O)(Nc1ccc(Oc2ncccn2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Nc1ccc(Oc2ncccn2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-(4-((3-Chloro-4-(2-pyrimidinyloxy)anilino)sulfonyl)phenyl)acetamide chemical structure, C18H15ClN4O4S, CAS 338413-30-2
N-(4-((3-Chloro-4-(2-pyrimidinyloxy)anilino)sulfonyl)phenyl)acetamide
CAS 338413-30-2C18H15ClN4O4S
Methyl 2-({4-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-2-methylanilino}sulfonyl)benzenecarboxylate chemical structure, C21H21N3O7S, CAS 866154-87-2
Methyl 2-({4-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-2-methylanilino}sulfonyl)benzenecarboxylate
CAS 866154-87-2C21H21N3O7S
N-[3-Chloro-4-(2-pyrimidinyloxy)phenyl]-4-methoxybenzenesulfonamide chemical structure, C17H14ClN3O4S, CAS 338413-19-7
N-[3-Chloro-4-(2-pyrimidinyloxy)phenyl]-4-methoxybenzenesulfonamide
CAS 338413-19-7C17H14ClN3O4S
4-(tert-Butyl)-N-{4-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-2-methylphenyl}benzenesulfonamide chemical structure, C23H27N3O5S, CAS 866154-88-3
4-(tert-Butyl)-N-{4-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-2-methylphenyl}benzenesulfonamide
CAS 866154-88-3C23H27N3O5S
2-Chloro-N-{4-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-2-methylphenyl}benzenesulfonamide chemical structure, C19H18ClN3O5S, CAS 866154-86-1
2-Chloro-N-{4-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-2-methylphenyl}benzenesulfonamide
CAS 866154-86-1C19H18ClN3O5S
N-[3-Chloro-4-(2-pyrimidinyloxy)phenyl]-4-fluorobenzenesulfonamide chemical structure, C16H11ClFN3O3S, CAS 338413-29-9
N-[3-Chloro-4-(2-pyrimidinyloxy)phenyl]-4-fluorobenzenesulfonamide
CAS 338413-29-9C16H11ClFN3O3S
4-Chloro-N-[3-chloro-4-(2-pyrimidinyloxy)phenyl]benzenesulfonamide chemical structure, C16H11Cl2N3O3S, CAS 338413-28-8
4-Chloro-N-[3-chloro-4-(2-pyrimidinyloxy)phenyl]benzenesulfonamide
CAS 338413-28-8C16H11Cl2N3O3S
Benzenesulfonamide, 3-chloro-N-[3-chloro-4-(2-pyrimidinyloxy)phenyl]- chemical structure, C16H11Cl2N3O3S, CAS 823782-55-4
Benzenesulfonamide, 3-chloro-N-[3-chloro-4-(2-pyrimidinyloxy)phenyl]-
CAS 823782-55-4C16H11Cl2N3O3S