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Murcko scaffold

Ring system with 3 rings and 18 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
12
With full pages
3
Scaffold SMILES

c1ccc(Oc2cc(-c3ccccc3)n[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Oc2cc(-c3ccccc3)n[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

[1-Methyl-5-(4-methylphenoxy)-3-phenyl-1H-pyrazol-4-yl]methyl 2-chloroacetate chemical structure, C20H19ClN2O3, CAS 318247-57-3
[1-Methyl-5-(4-methylphenoxy)-3-phenyl-1H-pyrazol-4-yl]methyl 2-chloroacetate
CAS 318247-57-3C20H19ClN2O3
[5-(4-Fluorophenoxy)-1-methyl-3-phenyl-1H-pyrazol-4-yl]methanol chemical structure, C17H15FN2O2, CAS 318247-67-5
[5-(4-Fluorophenoxy)-1-methyl-3-phenyl-1H-pyrazol-4-yl]methanol
CAS 318247-67-5C17H15FN2O2
{1-Methyl-3-phenyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl}methanol chemical structure, C18H15F3N2O2, CAS 318247-68-6
{1-Methyl-3-phenyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl}methanol
CAS 318247-68-6C18H15F3N2O2
5-(4-Chlorophenoxy)-1-methyl-3-phenyl-1H-pyrazole-4-carbaldehyde chemical structure, C17H13ClN2O2, CAS 109925-44-2
5-(4-Chlorophenoxy)-1-methyl-3-phenyl-1H-pyrazole-4-carbaldehyde
CAS 109925-44-2C17H13ClN2O2
1-Methyl-5-(4-methylphenoxy)-3-phenyl-1H-pyrazole-4-carbaldehyde chemical structure, C18H16N2O2, CAS 400073-98-5
1-Methyl-5-(4-methylphenoxy)-3-phenyl-1H-pyrazole-4-carbaldehyde
CAS 400073-98-5C18H16N2O2
[1-Methyl-5-(4-methylphenoxy)-3-phenyl-1H-pyrazol-4-yl]methanol chemical structure, C18H18N2O2, CAS 318234-01-4
[1-Methyl-5-(4-methylphenoxy)-3-phenyl-1H-pyrazol-4-yl]methanol
CAS 318234-01-4C18H18N2O2
1-(Isobutyl{[5-(4-methoxyphenoxy)-1-methyl-3-phenyl-1H-pyrazol-4-yl]methyl}amino)-2-propanol chemical structure, C25H33N3O3, CAS 1189456-29-8
1-(Isobutyl{[5-(4-methoxyphenoxy)-1-methyl-3-phenyl-1H-pyrazol-4-yl]methyl}amino)-2-propanol
CAS 1189456-29-8C25H33N3O3
1-(tert-Butoxy)-3-[{[5-(2,4-difluorophenoxy)-1-methyl-3-phenyl-1H-pyrazol-4-yl]methyl}(isobutyl)amino]-2-propanol chemical structure, C28H37F2N3O3, CAS 1184970-70-4
1-(tert-Butoxy)-3-[{[5-(2,4-difluorophenoxy)-1-methyl-3-phenyl-1H-pyrazol-4-yl]methyl}(isobutyl)amino]-2-propanol
CAS 1184970-70-4C28H37F2N3O3
3-(3-Bromophenyl)-5-[4-(dimethoxymethyl)phenoxy]-1-ethyl-1H-pyrazole chemical structure, C20H21BrN2O3, CAS 1289203-73-1
3-(3-Bromophenyl)-5-[4-(dimethoxymethyl)phenoxy]-1-ethyl-1H-pyrazole
CAS 1289203-73-1C20H21BrN2O3
4-{[3-(3-Bromophenyl)-1-ethyl-1H-pyrazol-5-yl]oxy}benzaldehyde chemical structure, C18H15BrN2O2, CAS 1289203-72-0
4-{[3-(3-Bromophenyl)-1-ethyl-1H-pyrazol-5-yl]oxy}benzaldehyde
CAS 1289203-72-0C18H15BrN2O2
3-[1-Ethyl-5-(4-formylphenoxy)-1H-pyrazol-3-yl]benzonitrile chemical structure, C19H15N3O2, CAS 1289203-40-2
3-[1-Ethyl-5-(4-formylphenoxy)-1H-pyrazol-3-yl]benzonitrile
CAS 1289203-40-2C19H15N3O2
3-(4-Bromophenoxy)-5-phenyl-1H-pyrazole-4-carbaldehyde chemical structure, C16H11BrN2O2, CAS 1305332-68-6
3-(4-Bromophenoxy)-5-phenyl-1H-pyrazole-4-carbaldehyde
CAS 1305332-68-6C16H11BrN2O2