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Murcko scaffold

Piberaline scaffold

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
7
With full pages
2
Scaffold SMILES

O=C(c1ccccn1)N1CCN(Cc2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Piberaline page
Murcko scaffold O=C(c1ccccn1)N1CCN(Cc2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Piberaline chemical structure, C17H19N3O, CAS 39640-15-8
Piberaline
CAS 39640-15-8C17H19N3O
Piperaline fumarate chemical structure, C21H23N3O5, CAS 39640-14-7
Piperaline fumarate
CAS 39640-14-7C21H23N3O5
1-Benzyl-4-[4,6-bis(trifluoromethyl)pyridine-2-carbonyl]piperazine chemical structure, C19H17F6N3O, CAS 1092345-39-5
1-Benzyl-4-[4,6-bis(trifluoromethyl)pyridine-2-carbonyl]piperazine
CAS 1092345-39-5C19H17F6N3O
1-Benzyl-4-[3-(trifluoromethyl)pyridine-2-carbonyl]piperazine chemical structure, C18H18F3N3O, CAS 1092345-60-2
1-Benzyl-4-[3-(trifluoromethyl)pyridine-2-carbonyl]piperazine
CAS 1092345-60-2C18H18F3N3O
1-(3,6-Dichloropyridine-2-carbonyl)-4-[(3,4-dimethoxyphenyl)methyl]piperazine chemical structure, C19H21Cl2N3O3, CAS 1111604-93-3
1-(3,6-Dichloropyridine-2-carbonyl)-4-[(3,4-dimethoxyphenyl)methyl]piperazine
CAS 1111604-93-3C19H21Cl2N3O3
Methyl 2-(2-chlorophenyl)-2-[4-(3,6-dichloropyridine-2-carbonyl)piperazin-1-yl]acetate chemical structure, C19H18Cl3N3O3, CAS 1214168-03-2
Methyl 2-(2-chlorophenyl)-2-[4-(3,6-dichloropyridine-2-carbonyl)piperazin-1-yl]acetate
CAS 1214168-03-2C19H18Cl3N3O3
1-Benzyl-4-(6-bromopyridine-2-carbonyl)piperazine chemical structure, C17H18BrN3O, CAS 1876755-44-0
1-Benzyl-4-(6-bromopyridine-2-carbonyl)piperazine
CAS 1876755-44-0C17H18BrN3O