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Murcko scaffold

2-Phenyl-N-(thiophen-2-ylmethyl)acetamide scaffold

27 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
27
With full pages
3
Scaffold SMILES

O=C(Cc1ccccc1)NCc1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-N-(thiophen-2-ylmethyl)acetamide page
Murcko scaffold O=C(Cc1ccccc1)NCc1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

2-(3,4-Diethoxyphenyl)-N-(2-thienylmethyl)acetamide chemical structure, C17H21NO3S, CAS 522597-91-7
2-(3,4-Diethoxyphenyl)-N-(2-thienylmethyl)acetamide
CAS 522597-91-7C17H21NO3S
2-Phenyl-N-(thiophen-2-ylmethyl)acetamide chemical structure, C13H13NOS, CAS 99329-49-4
2-Phenyl-N-(thiophen-2-ylmethyl)acetamide
CAS 99329-49-4C13H13NOS
2-(4-Nitrophenyl)-N-(thiophen-2-ylmethyl)acetamide chemical structure, C13H12N2O3S, CAS 546069-12-9
2-(4-Nitrophenyl)-N-(thiophen-2-ylmethyl)acetamide
CAS 546069-12-9C13H12N2O3S
2-(3,4-Dimethoxyphenyl)-N-(2-thienylmethyl)acetamide chemical structure, C15H17NO3S, CAS 438455-90-4
2-(3,4-Dimethoxyphenyl)-N-(2-thienylmethyl)acetamide
CAS 438455-90-4C15H17NO3S
2-(2-Fluorophenyl)-N-(thiophen-2-ylmethyl)acetamide chemical structure, C13H12FNOS, CAS 717868-50-3
2-(2-Fluorophenyl)-N-(thiophen-2-ylmethyl)acetamide
CAS 717868-50-3C13H12FNOS
2-(2-Chlorophenyl)-N-(thiophen-2-ylmethyl)acetamide chemical structure, C13H12ClNOS, CAS 775301-63-8
2-(2-Chlorophenyl)-N-(thiophen-2-ylmethyl)acetamide
CAS 775301-63-8C13H12ClNOS
2-(2-Chloro-6-fluorophenyl)-N-(thiophen-2-ylmethyl)acetamide chemical structure, C13H11ClFNOS, CAS 749877-04-1
2-(2-Chloro-6-fluorophenyl)-N-(thiophen-2-ylmethyl)acetamide
CAS 749877-04-1C13H11ClFNOS
2-(2-Nitrophenyl)-N-(thiophen-2-ylmethyl)acetamide chemical structure, C13H12N2O3S, CAS 777872-85-2
2-(2-Nitrophenyl)-N-(thiophen-2-ylmethyl)acetamide
CAS 777872-85-2C13H12N2O3S
2-Cyano-2-phenyl-N-(thiophen-2-ylmethyl)acetamide chemical structure, C14H12N2OS, CAS 695175-60-1
2-Cyano-2-phenyl-N-(thiophen-2-ylmethyl)acetamide
CAS 695175-60-1C14H12N2OS
2-Phenyl-N-[1-(thiophen-2-yl)ethyl]acetamide chemical structure, C14H15NOS, CAS 330828-29-0
2-Phenyl-N-[1-(thiophen-2-yl)ethyl]acetamide
CAS 330828-29-0C14H15NOS
2-(2-Methoxyphenyl)-N-(thiophen-2-ylmethyl)acetamide chemical structure, C14H15NO2S, CAS 136916-33-1
2-(2-Methoxyphenyl)-N-(thiophen-2-ylmethyl)acetamide
CAS 136916-33-1C14H15NO2S
2-(3-Methylphenyl)-N-(thiophen-2-ylmethyl)acetamide chemical structure, C14H15NOS, CAS 898139-06-5
2-(3-Methylphenyl)-N-(thiophen-2-ylmethyl)acetamide
CAS 898139-06-5C14H15NOS
2-(4-Acetamidophenyl)-N-[(thiophen-2-yl)methyl]acetamide chemical structure, C15H16N2O2S, CAS 878569-21-2
2-(4-Acetamidophenyl)-N-[(thiophen-2-yl)methyl]acetamide
CAS 878569-21-2C15H16N2O2S
2-(2-Chloro-6-fluorophenyl)-N-(1-(thiophen-2-yl)ethyl)acetamide chemical structure, C14H13ClFNOS, CAS 1037969-60-0
2-(2-Chloro-6-fluorophenyl)-N-(1-(thiophen-2-yl)ethyl)acetamide
CAS 1037969-60-0C14H13ClFNOS
(I+/-S)-I+/--Amino-N-(2-thienylmethyl)benzeneacetamide chemical structure, C13H14N2OS, CAS 1177225-43-2
(I+/-S)-I+/--Amino-N-(2-thienylmethyl)benzeneacetamide
CAS 1177225-43-2C13H14N2OS
2,2-Dimethyl-N-[4-({[(thiophen-2-yl)methyl]carbamoyl}methyl)phenyl]propanamide chemical structure, C18H22N2O2S, CAS 1060251-89-9
2,2-Dimethyl-N-[4-({[(thiophen-2-yl)methyl]carbamoyl}methyl)phenyl]propanamide
CAS 1060251-89-9C18H22N2O2S
2-Methoxy-N-[4-({[(thiophen-2-yl)methyl]carbamoyl}methyl)phenyl]acetamide chemical structure, C16H18N2O3S, CAS 1060313-27-0
2-Methoxy-N-[4-({[(thiophen-2-yl)methyl]carbamoyl}methyl)phenyl]acetamide
CAS 1060313-27-0C16H18N2O3S
Methyl N-[4-({[(thiophen-2-yl)methyl]carbamoyl}methyl)phenyl]carbamate chemical structure, C15H16N2O3S, CAS 1060356-14-0
Methyl N-[4-({[(thiophen-2-yl)methyl]carbamoyl}methyl)phenyl]carbamate
CAS 1060356-14-0C15H16N2O3S
2-(4-Methanesulfonamidophenyl)-N-[(thiophen-2-yl)methyl]acetamide chemical structure, C14H16N2O3S2, CAS 1060328-80-4
2-(4-Methanesulfonamidophenyl)-N-[(thiophen-2-yl)methyl]acetamide
CAS 1060328-80-4C14H16N2O3S2
2-Amino-2-phenyl-N-(thiophen-2-ylmethyl)acetamide chemical structure, C13H14N2OS, CAS 1218009-07-4
2-Amino-2-phenyl-N-(thiophen-2-ylmethyl)acetamide
CAS 1218009-07-4C13H14N2OS
2-(4-Aminophenyl)-N-(thiophen-2-ylmethyl)acetamide chemical structure, C13H14N2OS, CAS 1099661-02-5
2-(4-Aminophenyl)-N-(thiophen-2-ylmethyl)acetamide
CAS 1099661-02-5C13H14N2OS
Ethyl 4-oxo-4-((4-(2-oxo-2-((thiophen-2-ylmethyl)amino)ethyl)phenyl)amino)butanoate chemical structure, C19H22N2O4S, CAS 1206988-51-3
Ethyl 4-oxo-4-((4-(2-oxo-2-((thiophen-2-ylmethyl)amino)ethyl)phenyl)amino)butanoate
CAS 1206988-51-3C19H22N2O4S
N-[(4-Bromothiophen-2-yl)methyl]-2-(4-fluorophenyl)acetamide chemical structure, C13H11BrFNOS, CAS 1457265-48-3
N-[(4-Bromothiophen-2-yl)methyl]-2-(4-fluorophenyl)acetamide
CAS 1457265-48-3C13H11BrFNOS
N-[(4-Bromothiophen-2-yl)methyl]-2-phenylacetamide chemical structure, C13H12BrNOS, CAS 1455522-16-3
N-[(4-Bromothiophen-2-yl)methyl]-2-phenylacetamide
CAS 1455522-16-3C13H12BrNOS