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Murcko scaffold

Ring system with 3 rings and 20 atoms

22 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 20
Chemicals: 22
With full pages: 5

Scaffold SMILES

O=S(=O)(c1ccccc1)c1cnc(-c2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=S(=O)(c1ccccc1)c1cnc(-c2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

S-[5-(4-Methylphenyl)sulfonyl-2-phenyl-1H-imidazol-4-yl] ethanethioate chemical structure, C18H16N2O3S2, CAS 324579-69-3

S-[5-(4-Methylphenyl)sulfonyl-2-phenyl-1H-imidazol-4-yl] ethanethioate

CAS 324579-69-3C₁₈H₁₆N₂O₃S₂

2-(4-Methoxyphenyl)-5-(methylthio)-4-tosyl-1H-imidazole chemical structure, C18H18N2O3S2, CAS 164398-67-8

2-(4-Methoxyphenyl)-5-(methylthio)-4-tosyl-1H-imidazole

CAS 164398-67-8C₁₈H₁₈N₂O₃S₂

({4-[(4-Methylphenyl)sulfonyl]-2-phenyl-1H-imidazol-5-yl}sulfanyl)acetic acid chemical structure, C18H16N2O4S2, CAS 931694-78-9

({4-[(4-Methylphenyl)sulfonyl]-2-phenyl-1H-imidazol-5-yl}sulfanyl)acetic acid

CAS 931694-78-9C₁₈H₁₆N₂O₄S₂

2-((2-Phenyl-4-tosyl-1H-imidazol-5-yl)thio)propanoic acid chemical structure, C19H18N2O4S2, CAS 931733-92-5

2-((2-Phenyl-4-tosyl-1H-imidazol-5-yl)thio)propanoic acid

CAS 931733-92-5C₁₉H₁₈N₂O₄S₂

2-((2-Phenyl-4-tosyl-1H-imidazol-5-yl)thio)acetamide chemical structure, C18H17N3O3S2, CAS 931324-41-3

2-((2-Phenyl-4-tosyl-1H-imidazol-5-yl)thio)acetamide

CAS 931324-41-3C₁₈H₁₇N₃O₃S₂

2-{[2-Phenyl-4-(phenylsulfonyl)-1H-imidazol-5-yl]sulfanyl}-N-(propan-2-yl)acetamide chemical structure, C20H21N3O3S2, CAS 950304-91-3

2-{[2-Phenyl-4-(phenylsulfonyl)-1H-imidazol-5-yl]sulfanyl}-N-(propan-2-yl)acetamide

CAS 950304-91-3C₂₀H₂₁N₃O₃S₂

2-((4-(Phenylsulfonyl)-2-(p-tolyl)-1H-imidazol-5-yl)thio)-N-propylacetamide chemical structure, C21H23N3O3S2, CAS 950420-78-7

2-((4-(Phenylsulfonyl)-2-(p-tolyl)-1H-imidazol-5-yl)thio)-N-propylacetamide

CAS 950420-78-7C₂₁H₂₃N₃O₃S₂

N-(tert-Butyl)-2-((2-phenyl-4-tosyl-1H-imidazol-5-yl)thio)acetamide chemical structure, C22H25N3O3S2, CAS 950420-87-8

N-(tert-Butyl)-2-((2-phenyl-4-tosyl-1H-imidazol-5-yl)thio)acetamide

CAS 950420-87-8C₂₂H₂₅N₃O₃S₂

Benzene, 2-(4-methoxyphenyl)-5-(4-methylphenyl)sulfonyl-4-methylsulfanyl-1H-imidazole chemical structure, C24H24N2O3S2, CAS 1179460-76-4

Benzene, 2-(4-methoxyphenyl)-5-(4-methylphenyl)sulfonyl-4-methylsulfanyl-1H-imidazole

CAS 1179460-76-4C₂₄H₂₄N₂O₃S₂

2-((2-Phenyl-4-(phenylsulfonyl)-1H-imidazol-5-yl)thio)acetamide chemical structure, C17H15N3O3S2, CAS 950351-53-8

2-((2-Phenyl-4-(phenylsulfonyl)-1H-imidazol-5-yl)thio)acetamide

CAS 950351-53-8C₁₇H₁₅N₃O₃S₂

2-((2-Phenyl-4-(phenylsulfonyl)-1H-imidazol-5-yl)thio)-N-propylacetamide chemical structure, C20H21N3O3S2, CAS 950395-85-4

2-((2-Phenyl-4-(phenylsulfonyl)-1H-imidazol-5-yl)thio)-N-propylacetamide

CAS 950395-85-4C₂₀H₂₁N₃O₃S₂

2-((4-(Phenylsulfonyl)-2-(p-tolyl)-1H-imidazol-5-yl)thio)acetamide chemical structure, C18H17N3O3S2, CAS 950304-99-1

2-((4-(Phenylsulfonyl)-2-(p-tolyl)-1H-imidazol-5-yl)thio)acetamide

CAS 950304-99-1C₁₈H₁₇N₃O₃S₂

2-{[4-(Benzenesulfonyl)-2-(4-methylphenyl)-1H-imidazol-5-yl]sulfanyl}-N-(propan-2-yl)acetamide chemical structure, C21H23N3O3S2, CAS 950396-46-0

2-{[4-(Benzenesulfonyl)-2-(4-methylphenyl)-1H-imidazol-5-yl]sulfanyl}-N-(propan-2-yl)acetamide

CAS 950396-46-0C₂₁H₂₃N₃O₃S₂

N-(sec-Butyl)-2-((2-phenyl-4-tosyl-1H-imidazol-5-yl)thio)acetamide chemical structure, C22H25N3O3S2, CAS 950396-66-4

N-(sec-Butyl)-2-((2-phenyl-4-tosyl-1H-imidazol-5-yl)thio)acetamide

CAS 950396-66-4C₂₂H₂₅N₃O₃S₂

N-Isopropyl-2-((2-phenyl-4-tosyl-1H-imidazol-5-yl)thio)acetamide chemical structure, C21H23N3O3S2, CAS 950421-14-4

N-Isopropyl-2-((2-phenyl-4-tosyl-1H-imidazol-5-yl)thio)acetamide

CAS 950421-14-4C₂₁H₂₃N₃O₃S₂

2-((4-(Phenylsulfonyl)-2-(p-tolyl)-1H-imidazol-5-yl)thio)acetic acid chemical structure, C18H16N2O4S2, CAS 1040675-22-6

2-((4-(Phenylsulfonyl)-2-(p-tolyl)-1H-imidazol-5-yl)thio)acetic acid

CAS 1040675-22-6C₁₈H₁₆N₂O₄S₂

N,N-Dimethyl-2-((2-phenyl-4-tosyl-1H-imidazol-5-yl)thio)acetamide chemical structure, C20H21N3O3S2, CAS 1040638-95-6

N,N-Dimethyl-2-((2-phenyl-4-tosyl-1H-imidazol-5-yl)thio)acetamide

CAS 1040638-95-6C₂₀H₂₁N₃O₃S₂

N,N-Dimethyl-2-((2-phenyl-4-(phenylsulfonyl)-1H-imidazol-5-yl)thio)acetamide chemical structure, C19H19N3O3S2, CAS 1021106-09-1

N,N-Dimethyl-2-((2-phenyl-4-(phenylsulfonyl)-1H-imidazol-5-yl)thio)acetamide

CAS 1021106-09-1C₁₉H₁₉N₃O₃S₂

N-(2-Methylpropyl)-2-{[2-phenyl-4-(phenylsulfonyl)-1H-imidazol-5-yl]sulfanyl}acetamide chemical structure, C21H23N3O3S2, CAS 1021037-45-5

N-(2-Methylpropyl)-2-{[2-phenyl-4-(phenylsulfonyl)-1H-imidazol-5-yl]sulfanyl}acetamide

CAS 1021037-45-5C₂₁H₂₃N₃O₃S₂

2-((2-Phenyl-4-tosyl-1H-imidazol-5-yl)thio)-N-propylacetamide chemical structure, C21H23N3O3S2, CAS 1021106-13-7

2-((2-Phenyl-4-tosyl-1H-imidazol-5-yl)thio)-N-propylacetamide

CAS 1021106-13-7C₂₁H₂₃N₃O₃S₂

(5-Benzenesulfonyl-2-phenyl-3H-imidazol-4-ylsulfanyl)-acetic acid chemical structure, C17H14N2O4S2, CAS 1171935-29-7

(5-Benzenesulfonyl-2-phenyl-3H-imidazol-4-ylsulfanyl)-acetic acid

CAS 1171935-29-7C₁₇H₁₄N₂O₄S₂

Potassium [4-(benzenesulfonyl)-2-phenyl-1H-imidazol-5-yl]sulfanide chemical structure, C15H11KN2O2S2, CAS 164398-56-5

Potassium [4-(benzenesulfonyl)-2-phenyl-1H-imidazol-5-yl]sulfanide

CAS 164398-56-5C₁₅H₁₁KN₂O₂S₂