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Murcko scaffold

Ring system with 3 rings and 22 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
17
With full pages
8
Scaffold SMILES

O=C1CCC(N2C(=O)C=C(Nc3ccccc3)C2=O)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCC(N2C(=O)C=C(Nc3ccccc3)C2=O)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

4-{[1-(2,6-Dioxopiperidin-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]amino}benzoic acid chemical structure, C16H13N3O6, CAS 2703768-12-9
4-{[1-(2,6-Dioxopiperidin-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]amino}benzoic acid
CAS 2703768-12-9C16H13N3O6
2-{[1-(2,6-Dioxopiperidin-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]amino}benzoic acid chemical structure, C16H13N3O6, CAS 2703760-62-5
2-{[1-(2,6-Dioxopiperidin-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]amino}benzoic acid
CAS 2703760-62-5C16H13N3O6
3-{3-[(4-Bromophenyl)amino]-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl}piperidine-2,6-dione chemical structure, C15H12BrN3O4, CAS 2703764-28-5
3-{3-[(4-Bromophenyl)amino]-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl}piperidine-2,6-dione
CAS 2703764-28-5C15H12BrN3O4
3-{3-[(4-Hydroxyphenyl)amino]-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl}piperidine-2,6-dione chemical structure, C15H13N3O5, CAS 2703763-98-6
3-{3-[(4-Hydroxyphenyl)amino]-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl}piperidine-2,6-dione
CAS 2703763-98-6C15H13N3O5
3-{3-[(4-Ethynylphenyl)amino]-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl}piperidine-2,6-dione chemical structure, C17H13N3O4, CAS 2703760-48-7
3-{3-[(4-Ethynylphenyl)amino]-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl}piperidine-2,6-dione
CAS 2703760-48-7C17H13N3O4
3-{3-[(3-Ethynylphenyl)amino]-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl}piperidine-2,6-dione chemical structure, C17H13N3O4, CAS 2703770-72-1
3-{3-[(3-Ethynylphenyl)amino]-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl}piperidine-2,6-dione
CAS 2703770-72-1C17H13N3O4
3-{[1-(2,6-Dioxopiperidin-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]amino}benzoic acid chemical structure, C16H13N3O6, CAS 2703767-51-3
3-{[1-(2,6-Dioxopiperidin-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]amino}benzoic acid
CAS 2703767-51-3C16H13N3O6
3-(3-{[3-(3-Azidopropoxy)phenyl]amino}-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)piperidine-2,6-dione chemical structure, C18H18N6O5, CAS 2866308-86-1
3-(3-{[3-(3-Azidopropoxy)phenyl]amino}-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)piperidine-2,6-dione
CAS 2866308-86-1C18H18N6O5
3-(3-{[3-(4-Azidobutoxy)phenyl]amino}-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)piperidine-2,6-dione chemical structure, C19H20N6O5, CAS 2866318-13-8
3-(3-{[3-(4-Azidobutoxy)phenyl]amino}-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)piperidine-2,6-dione
CAS 2866318-13-8C19H20N6O5
3-(3-{[3-(2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethoxy)phenyl]amino}-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)piperidine-2,6-dione chemical structure, C23H28N6O8, CAS 2866307-41-5
3-(3-{[3-(2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethoxy)phenyl]amino}-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)piperidine-2,6-dione
CAS 2866307-41-5C23H28N6O8
3-[3-({3-[(14-Azido-3,6,9,12-tetraoxatetradecan-1-yl)oxy]phenyl}amino)-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl]piperidine-2,6-dione chemical structure, C25H32N6O9, CAS 2866307-27-7
3-[3-({3-[(14-Azido-3,6,9,12-tetraoxatetradecan-1-yl)oxy]phenyl}amino)-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl]piperidine-2,6-dione
CAS 2866307-27-7C25H32N6O9
3-(3-{[3-(2-Azidoethoxy)phenyl]amino}-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)piperidine-2,6-dione chemical structure, C17H16N6O5, CAS 2866319-20-0
3-(3-{[3-(2-Azidoethoxy)phenyl]amino}-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)piperidine-2,6-dione
CAS 2866319-20-0C17H16N6O5
3-[3-({3-[(6-Azidohexyl)oxy]phenyl}amino)-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl]piperidine-2,6-dione chemical structure, C21H24N6O5, CAS 2866307-21-1
3-[3-({3-[(6-Azidohexyl)oxy]phenyl}amino)-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl]piperidine-2,6-dione
CAS 2866307-21-1C21H24N6O5
3-[3-({3-[2-(2-Azidoethoxy)ethoxy]phenyl}amino)-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl]piperidine-2,6-dione chemical structure, C19H20N6O6, CAS 2866307-66-4
3-[3-({3-[2-(2-Azidoethoxy)ethoxy]phenyl}amino)-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl]piperidine-2,6-dione
CAS 2866307-66-4C19H20N6O6
3-{3-[(3-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}phenyl)amino]-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl}piperidine-2,6-dione chemical structure, C21H24N6O7, CAS 2866319-11-9
3-{3-[(3-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}phenyl)amino]-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl}piperidine-2,6-dione
CAS 2866319-11-9C21H24N6O7
3-[3-({3-[(5-Azidopentyl)oxy]phenyl}amino)-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl]piperidine-2,6-dione chemical structure, C20H22N6O5, CAS 2866318-30-9
3-[3-({3-[(5-Azidopentyl)oxy]phenyl}amino)-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl]piperidine-2,6-dione
CAS 2866318-30-9C20H22N6O5
3-[3-({3-[3-(3-Azidopropoxy)propoxy]phenyl}amino)-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl]piperidine-2,6-dione chemical structure, C21H24N6O6, CAS 2866307-82-4
3-[3-({3-[3-(3-Azidopropoxy)propoxy]phenyl}amino)-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl]piperidine-2,6-dione
CAS 2866307-82-4C21H24N6O6