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Murcko scaffold

Ring system with 3 rings and 20 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
20
With full pages
6
Scaffold SMILES

c1ccc(OCCCN2CCc3ccccc3C2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(OCCCN2CCc3ccccc3C2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

1-(3,4-Dihydro-1H-isoquinolin-2-yl)-3-(3-methoxyphenoxy)propan-2-ol chemical structure, C19H23NO3, CAS 439128-96-8
1-(3,4-Dihydro-1H-isoquinolin-2-yl)-3-(3-methoxyphenoxy)propan-2-ol
CAS 439128-96-8C19H23NO3
1-(3,4-Dihydro-1H-isoquinolin-2-yl)-3-(2,4-dimethyl-phenoxy)-propan-2-ol chemical structure, C20H25NO2, CAS 439129-13-2
1-(3,4-Dihydro-1H-isoquinolin-2-yl)-3-(2,4-dimethyl-phenoxy)-propan-2-ol
CAS 439129-13-2C20H25NO2
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-(3-methoxyphenoxy)propan-2-ol hydrochloride chemical structure, C19H24ClNO3, CAS 478614-53-8
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-(3-methoxyphenoxy)propan-2-ol hydrochloride
CAS 478614-53-8C19H24ClNO3
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-(2,4-dimethylphenoxy)propan-2-ol hydrochloride chemical structure, C20H26ClNO2, CAS 473267-05-9
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-(2,4-dimethylphenoxy)propan-2-ol hydrochloride
CAS 473267-05-9C20H26ClNO2
1-(3,4-Dihydro-2(1H)-isoquinolinyl)-3-(2-isopropyl-5-methylphenoxy)-2-propanol chemical structure, C22H29NO2, CAS 327104-54-1
1-(3,4-Dihydro-2(1H)-isoquinolinyl)-3-(2-isopropyl-5-methylphenoxy)-2-propanol
CAS 327104-54-1C22H29NO2
1-(2,4-Dichlorophenoxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol hydrochloride chemical structure, C18H20Cl3NO2, CAS 474303-06-5
1-(2,4-Dichlorophenoxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol hydrochloride
CAS 474303-06-5C18H20Cl3NO2
1-(2,4-Dichlorophenoxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol chemical structure, C18H19Cl2NO2, CAS 753444-37-0
1-(2,4-Dichlorophenoxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol
CAS 753444-37-0C18H19Cl2NO2
1-(3,4-Dihydro-1H-isoquinolin-2-yl)-3-(2,6-dimethylphenoxy)propan-2-ol chemical structure, C20H25NO2, CAS 618066-87-8
1-(3,4-Dihydro-1H-isoquinolin-2-yl)-3-(2,6-dimethylphenoxy)propan-2-ol
CAS 618066-87-8C20H25NO2
1-(2-Chloro-4-fluorophenoxy)-3-(3,4-dihydro-1H-isoquinolin-2-yl)propan-2-ol chemical structure, C18H19ClFNO2, CAS 522603-33-4
1-(2-Chloro-4-fluorophenoxy)-3-(3,4-dihydro-1H-isoquinolin-2-yl)propan-2-ol
CAS 522603-33-4C18H19ClFNO2
1-{4-[3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropoxy]phenyl}ethanone chemical structure, C20H23NO3, CAS 524710-91-6
1-{4-[3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropoxy]phenyl}ethanone
CAS 524710-91-6C20H23NO3
1-(4-Methoxyphenoxy)-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-2-ol hydrochloride chemical structure, C19H24ClNO3, CAS 474263-96-2
1-(4-Methoxyphenoxy)-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-2-ol hydrochloride
CAS 474263-96-2C19H24ClNO3
1-(1,2,3,4-Tetrahydroisoquinolin-2-yl)-3-(2,3,5-trimethylphenoxy)propan-2-ol hydrochloride chemical structure, C21H28ClNO2, CAS 1216731-47-3
1-(1,2,3,4-Tetrahydroisoquinolin-2-yl)-3-(2,3,5-trimethylphenoxy)propan-2-ol hydrochloride
CAS 1216731-47-3C21H28ClNO2
1-(4-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropoxy)phenyl)ethanone hydrochloride chemical structure, C20H24ClNO3, CAS 1177966-31-2
1-(4-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropoxy)phenyl)ethanone hydrochloride
CAS 1177966-31-2C20H24ClNO3
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-(2-methoxyphenoxy)propan-2-ol hydrochloride chemical structure, C19H24ClNO3, CAS 1185675-06-2
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-(2-methoxyphenoxy)propan-2-ol hydrochloride
CAS 1185675-06-2C19H24ClNO3
1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(2-methoxyphenoxy)propan-2-ol hydrochloride chemical structure, C21H28ClNO5, CAS 1185677-05-7
1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(2-methoxyphenoxy)propan-2-ol hydrochloride
CAS 1185677-05-7C21H28ClNO5
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-(p-tolyloxy)propan-2-ol hydrochloride chemical structure, C19H24ClNO2, CAS 1185704-24-8
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-(p-tolyloxy)propan-2-ol hydrochloride
CAS 1185704-24-8C19H24ClNO2
1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(p-tolyloxy)propan-2-ol hydrochloride chemical structure, C21H28ClNO4, CAS 1185432-23-8
1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(p-tolyloxy)propan-2-ol hydrochloride
CAS 1185432-23-8C21H28ClNO4
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-(2-isopropyl-5-methylphenoxy)propan-2-ol oxalate chemical structure, C24H31NO6, CAS 1217077-33-2
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-(2-isopropyl-5-methylphenoxy)propan-2-ol oxalate
CAS 1217077-33-2C24H31NO6
1-(3-Bromophenoxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol chemical structure, C18H20BrNO2, CAS 1088176-04-8
1-(3-Bromophenoxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol
CAS 1088176-04-8C18H20BrNO2
1-(2,4-Dibromophenoxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol hydrochloride chemical structure, C18H20Br2ClNO2, CAS 1185015-48-8
1-(2,4-Dibromophenoxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol hydrochloride
CAS 1185015-48-8C18H20Br2ClNO2