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Murcko scaffold

Ring system with 3 rings and 19 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
20
With full pages
5
Scaffold SMILES

O=C(c1ccccc1)N1CCCC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)N1CCCC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

1-(4-Bromobenzoyl)-2-phenylpyrrolidine-2-carbonitrile chemical structure, C18H15BrN2O, CAS 333755-91-2
1-(4-Bromobenzoyl)-2-phenylpyrrolidine-2-carbonitrile
CAS 333755-91-2C18H15BrN2O
1-(4-Methoxy-3-nitrobenzoyl)-2-phenylpyrrolidine-2-carbonitrile chemical structure, C19H17N3O4, CAS 355819-97-5
1-(4-Methoxy-3-nitrobenzoyl)-2-phenylpyrrolidine-2-carbonitrile
CAS 355819-97-5C19H17N3O4
1-(4-Bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide chemical structure, C18H17BrN2O2, CAS 376617-77-5
1-(4-Bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide
CAS 376617-77-5C18H17BrN2O2
1-(2-Bromobenzoyl)-2-phenylpyrrolidine-2-carbonitrile chemical structure, C18H15BrN2O, CAS 376606-94-9
1-(2-Bromobenzoyl)-2-phenylpyrrolidine-2-carbonitrile
CAS 376606-94-9C18H15BrN2O
1-(2-Bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide chemical structure, C18H17BrN2O2, CAS 355820-04-1
1-(2-Bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide
CAS 355820-04-1C18H17BrN2O2
Methyl 1-benzoyl-2-phenylpyrrolidine-3-carboxylate chemical structure, C19H19NO3
Methyl 1-benzoyl-2-phenylpyrrolidine-3-carboxylate
C19H19NO3
Methyl (2R,3S)-1-benzoyl-2-phenylpyrrolidine-3-carboxylate chemical structure, C19H19NO3
Methyl (2R,3S)-1-benzoyl-2-phenylpyrrolidine-3-carboxylate
C19H19NO3
4-{[2-(2-Methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol chemical structure, C18H19NO3, CAS 914296-85-8
4-{[2-(2-Methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol
CAS 914296-85-8C18H19NO3
4-[(2-Phenylpyrrolidin-1-yl)carbonyl]benzene-1,3-diol chemical structure, C17H17NO3, CAS 914296-89-2
4-[(2-Phenylpyrrolidin-1-yl)carbonyl]benzene-1,3-diol
CAS 914296-89-2C17H17NO3
4-(2-Phenylpyrrolidine-1-carbonyl)aniline chemical structure, C17H18N2O, CAS 1157003-33-2
4-(2-Phenylpyrrolidine-1-carbonyl)aniline
CAS 1157003-33-2C17H18N2O
Methyl 4-[1-(5-chloro-2,4-dihydroxybenzoyl)-2-pyrrolidinyl]-3-methylbenzoate chemical structure, C20H20ClNO5, CAS 914298-77-4
Methyl 4-[1-(5-chloro-2,4-dihydroxybenzoyl)-2-pyrrolidinyl]-3-methylbenzoate
CAS 914298-77-4C20H20ClNO5
2-(2-Chlorophenyl)-1-(2-fluorobenzoyl)pyrrolidine chemical structure, C17H15ClFNO, CAS 1174887-29-6
2-(2-Chlorophenyl)-1-(2-fluorobenzoyl)pyrrolidine
CAS 1174887-29-6C17H15ClFNO
(2-(4-Methoxyphenyl)pyrrolidin-1-yl)(phenyl)methanone chemical structure, C18H19NO2, CAS 1330848-20-8
(2-(4-Methoxyphenyl)pyrrolidin-1-yl)(phenyl)methanone
CAS 1330848-20-8C18H19NO2
Methyl 4-{1-[5-chloro-2,4-bis(methoxymethoxy)benzoyl]pyrrolidin-2-yl}-3-methylbenzoate chemical structure, C24H28ClNO7, CAS 914299-16-4
Methyl 4-{1-[5-chloro-2,4-bis(methoxymethoxy)benzoyl]pyrrolidin-2-yl}-3-methylbenzoate
CAS 914299-16-4C24H28ClNO7
Methyl 3-{1-[5-chloro-2,4-bis(methoxymethoxy)benzoyl]pyrrolidin-2-yl}-2-methylbenzoate chemical structure, C24H28ClNO7, CAS 914299-23-3
Methyl 3-{1-[5-chloro-2,4-bis(methoxymethoxy)benzoyl]pyrrolidin-2-yl}-2-methylbenzoate
CAS 914299-23-3C24H28ClNO7
(2-(4-Fluorophenyl)pyrrolidin-1-yl)(phenyl)methanone chemical structure, C17H16FNO, CAS 1355178-70-9
(2-(4-Fluorophenyl)pyrrolidin-1-yl)(phenyl)methanone
CAS 1355178-70-9C17H16FNO
(2-(2,6-Dimethoxyphenyl)pyrrolidin-1-yl)(phenyl)methanone chemical structure, C19H21NO3, CAS 1355218-77-7
(2-(2,6-Dimethoxyphenyl)pyrrolidin-1-yl)(phenyl)methanone
CAS 1355218-77-7C19H21NO3
(2-(2-Methoxyphenyl)pyrrolidin-1-yl)(phenyl)methanone chemical structure, C18H19NO2, CAS 1355181-25-7
(2-(2-Methoxyphenyl)pyrrolidin-1-yl)(phenyl)methanone
CAS 1355181-25-7C18H19NO2
cis-Methyl 1-benzoyl-2-phenylpyrrolidine-3-carboxylate chemical structure, C19H19NO3, CAS 89055-14-1
cis-Methyl 1-benzoyl-2-phenylpyrrolidine-3-carboxylate
CAS 89055-14-1C19H19NO3
trans-Methyl 1-benzoyl-2-phenylpyrrolidine-3-carboxylate chemical structure, C19H19NO3, CAS 89055-15-2
trans-Methyl 1-benzoyl-2-phenylpyrrolidine-3-carboxylate
CAS 89055-15-2C19H19NO3