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Murcko scaffold

2-Propen-1-one, 1-phenyl-3-(thienyl)- scaffold

121 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
121
With full pages
11
Scaffold SMILES

O=C(C=Cc1cccs1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Propen-1-one, 1-phenyl-3-(thienyl)- page
Murcko scaffold O=C(C=Cc1cccs1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 121 chemicals

4',5-Dichloro-2-thienylchalcone chemical structure, C13H8Cl2OS, CAS 22619-36-9
4',5-Dichloro-2-thienylchalcone
CAS 22619-36-9C13H8Cl2OS
2-Propen-1-one, 1-phenyl-3-(thienyl)- chemical structure, C13H10OS, CAS 89144-95-6
2-Propen-1-one, 1-phenyl-3-(thienyl)-
CAS 89144-95-6C13H10OS
1-(4-Chlorophenyl)-3-(thiophen-2-yl)prop-2-en-1-one chemical structure, C13H9ClOS, CAS 89144-97-8
1-(4-Chlorophenyl)-3-(thiophen-2-yl)prop-2-en-1-one
CAS 89144-97-8C13H9ClOS
1-(4-Methylphenyl)-3-(2-thienyl)-2-propen-1-one chemical structure, C14H12OS, CAS 6028-89-3
1-(4-Methylphenyl)-3-(2-thienyl)-2-propen-1-one
CAS 6028-89-3C14H12OS
4'-Methyl-3-(2-thienyl)acrylophenone chemical structure, C14H12OS, CAS 69837-03-2
4'-Methyl-3-(2-thienyl)acrylophenone
CAS 69837-03-2C14H12OS
3-(4-Bromo-2-thienyl)-1-(4-chloro-3-methylphenyl)prop-2-en-1-one chemical structure, C14H10BrClOS, CAS 219619-24-6
3-(4-Bromo-2-thienyl)-1-(4-chloro-3-methylphenyl)prop-2-en-1-one
CAS 219619-24-6C14H10BrClOS
2-Propen-1-one, 3-(5-methyl-2-thienyl)-1-(4-nitrophenyl)- chemical structure, C14H11NO3S, CAS 58235-89-5
2-Propen-1-one, 3-(5-methyl-2-thienyl)-1-(4-nitrophenyl)-
CAS 58235-89-5C14H11NO3S
2-Propen-1-one, 3-(5-bromo-2-thienyl)-1-(4-nitrophenyl)- chemical structure, C13H8BrNO3S, CAS 58235-90-8
2-Propen-1-one, 3-(5-bromo-2-thienyl)-1-(4-nitrophenyl)-
CAS 58235-90-8C13H8BrNO3S
3-(5-Bromothiophen-2-yl)-1-(4-methylphenyl)prop-2-en-1-one chemical structure, C14H11BrOS, CAS 73673-46-8
3-(5-Bromothiophen-2-yl)-1-(4-methylphenyl)prop-2-en-1-one
CAS 73673-46-8C14H11BrOS
(2E)-1-(4-Bromophenyl)-3-(thiophen-2-yl)prop-2-en-1-one chemical structure, C13H9BrOS, CAS 2910-79-4
(2E)-1-(4-Bromophenyl)-3-(thiophen-2-yl)prop-2-en-1-one
CAS 2910-79-4C13H9BrOS
(2E)-1-(4-Fluorophenyl)-3-(thiophen-2-yl)prop-2-en-1-one chemical structure, C13H9FOS, CAS 1345959-93-4
(2E)-1-(4-Fluorophenyl)-3-(thiophen-2-yl)prop-2-en-1-one
CAS 1345959-93-4C13H9FOS
(E)-1-(4-Ethoxyphenyl)-3-thiophen-2-ylprop-2-en-1-one chemical structure, C15H14O2S, CAS 6028-88-2
(E)-1-(4-Ethoxyphenyl)-3-thiophen-2-ylprop-2-en-1-one
CAS 6028-88-2C15H14O2S
(2E)-3-(5-Methylthiophen-2-yl)-1-(4-nitrophenyl)prop-2-en-1-one chemical structure, C14H11NO3S, CAS 1699750-47-4
(2E)-3-(5-Methylthiophen-2-yl)-1-(4-nitrophenyl)prop-2-en-1-one
CAS 1699750-47-4C14H11NO3S
(E)-3-(5-Methoxythiophen-2-yl)-1-(4-nitrophenyl)prop-2-en-1-one chemical structure, C14H11NO4S, CAS 62913-88-6
(E)-3-(5-Methoxythiophen-2-yl)-1-(4-nitrophenyl)prop-2-en-1-one
CAS 62913-88-6C14H11NO4S
(2E)-1-(3,4-Dimethoxyphenyl)-3-(3-methylthiophen-2-yl)prop-2-en-1-one chemical structure, C16H16O3S, CAS 337495-34-8
(2E)-1-(3,4-Dimethoxyphenyl)-3-(3-methylthiophen-2-yl)prop-2-en-1-one
CAS 337495-34-8C16H16O3S
RefChem:305901 chemical structure, C13H10O2S, CAS 2875-22-1
RefChem:305901
CAS 2875-22-1C13H10O2S
(2E)-1-(2-Hydroxy-4-methoxyphenyl)-3-(thiophen-2-yl)prop-2-en-1-one chemical structure, C14H12O3S, CAS 6622-60-2
(2E)-1-(2-Hydroxy-4-methoxyphenyl)-3-(thiophen-2-yl)prop-2-en-1-one
CAS 6622-60-2C14H12O3S
(E)-1-(4-Bromophenyl)-3-(5-bromothiophen-2-yl)prop-2-en-1-one chemical structure, C13H8Br2OS, CAS 22609-37-6
(E)-1-(4-Bromophenyl)-3-(5-bromothiophen-2-yl)prop-2-en-1-one
CAS 22609-37-6C13H8Br2OS
(2E)-1-(5-Chloro-2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-en-1-one chemical structure, C13H9ClO2S, CAS 7209-80-5
(2E)-1-(5-Chloro-2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-en-1-one
CAS 7209-80-5C13H9ClO2S
(Z)-2-Methyl-1-phenyl-3-thiophen-2-ylprop-2-en-1-one chemical structure, C14H12OS, CAS 67615-48-9
(Z)-2-Methyl-1-phenyl-3-thiophen-2-ylprop-2-en-1-one
CAS 67615-48-9C14H12OS
3-(4-Bromo-2-thienyl)-1-(4-fluorophenyl)prop-2-en-1-one chemical structure, C13H8BrFOS, CAS 1082708-51-7
3-(4-Bromo-2-thienyl)-1-(4-fluorophenyl)prop-2-en-1-one
CAS 1082708-51-7C13H8BrFOS
1-(4-Chlorophenyl)-3-(2-thienyl)prop-2-en-1-one chemical structure, C13H9ClOS, CAS 6028-91-7
1-(4-Chlorophenyl)-3-(2-thienyl)prop-2-en-1-one
CAS 6028-91-7C13H9ClOS
2-Propen-1-one, 1-phenyl-3-(2-thienyl)- chemical structure, C13H10OS, CAS 2910-81-8
2-Propen-1-one, 1-phenyl-3-(2-thienyl)-
CAS 2910-81-8C13H10OS
1-(4-Methoxyphenyl)-3-(2-thienyl)prop-2-en-1-one chemical structure, C14H12O2S, CAS 69837-02-1
1-(4-Methoxyphenyl)-3-(2-thienyl)prop-2-en-1-one
CAS 69837-02-1C14H12O2S