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Murcko scaffold

Ring system with 3 rings and 22 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
8
With full pages
3
Scaffold SMILES

O=C(NN=Cc1ccccn1)c1cc(-c2ccccc2)n[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccn1)c1cc(-c2ccccc2)n[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

(E)-N'-(Pyridin-2-ylmethylene)-3-(p-tolyl)-1H-pyrazole-5-carbohydrazide chemical structure, C17H15N5O, CAS 1285532-43-5
(E)-N'-(Pyridin-2-ylmethylene)-3-(p-tolyl)-1H-pyrazole-5-carbohydrazide
CAS 1285532-43-5C17H15N5O
(E)-3-(3-Ethoxyphenyl)-N'-(pyridin-2-ylmethylene)-1H-pyrazole-5-carbohydrazide chemical structure, C18H17N5O2, CAS 307350-70-5
(E)-3-(3-Ethoxyphenyl)-N'-(pyridin-2-ylmethylene)-1H-pyrazole-5-carbohydrazide
CAS 307350-70-5C18H17N5O2
3-(2-Ethoxyphenyl)-N'-(2-pyridinylmethylene)-1H-pyrazole-5-carbohydrazide chemical structure, C18H17N5O2, CAS 303107-80-4
3-(2-Ethoxyphenyl)-N'-(2-pyridinylmethylene)-1H-pyrazole-5-carbohydrazide
CAS 303107-80-4C18H17N5O2
3-(4-Isobutylphenyl)-N'-(2-pyridinylmethylene)-1H-pyrazole-5-carbohydrazide chemical structure, C20H21N5O, CAS 303104-95-2
3-(4-Isobutylphenyl)-N'-(2-pyridinylmethylene)-1H-pyrazole-5-carbohydrazide
CAS 303104-95-2C20H21N5O
(E)-3-(4-Ethoxy-3-methoxyphenyl)-N'-(pyridin-2-ylmethylene)-1H-pyrazole-5-carbohydrazide chemical structure, C19H19N5O3, CAS 1284270-45-6
(E)-3-(4-Ethoxy-3-methoxyphenyl)-N'-(pyridin-2-ylmethylene)-1H-pyrazole-5-carbohydrazide
CAS 1284270-45-6C19H19N5O3
(E)-3-(4-Isopropoxyphenyl)-N'-(pyridin-2-ylmethylene)-1H-pyrazole-5-carbohydrazide chemical structure, C19H19N5O2, CAS 1285535-65-0
(E)-3-(4-Isopropoxyphenyl)-N'-(pyridin-2-ylmethylene)-1H-pyrazole-5-carbohydrazide
CAS 1285535-65-0C19H19N5O2
3-(4-Ethylphenyl)-N-[(E)-pyridin-2-ylmethylideneamino]-1H-pyrazole-5-carboxamide chemical structure, C18H17N5O, CAS 402504-02-3
3-(4-Ethylphenyl)-N-[(E)-pyridin-2-ylmethylideneamino]-1H-pyrazole-5-carboxamide
CAS 402504-02-3C18H17N5O
(E)-3-(4-Butoxyphenyl)-N'-(pyridin-2-ylmethylene)-1H-pyrazole-5-carbohydrazide chemical structure, C20H21N5O2, CAS 1285612-22-7
(E)-3-(4-Butoxyphenyl)-N'-(pyridin-2-ylmethylene)-1H-pyrazole-5-carbohydrazide
CAS 1285612-22-7C20H21N5O2