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Murcko scaffold

Proline benzyl ester scaffold

97 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
97
With full pages
4
Scaffold SMILES

O=C(OCc1ccccc1)C1CCCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Proline benzyl ester page
Murcko scaffold O=C(OCc1ccccc1)C1CCCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 97 chemicals

Proline benzyl ester chemical structure, C12H15NO2, CAS 80089-25-4
Proline benzyl ester
CAS 80089-25-4C12H15NO2
t-Butyloxycarbonyl-cyanoalanylproline benzyl ester chemical structure, C21H27N3O5, CAS 132247-17-7
t-Butyloxycarbonyl-cyanoalanylproline benzyl ester
CAS 132247-17-7C21H27N3O5
Benzyl (2R)-pyrrolidine-2-carboxylate chemical structure, C12H15NO2, CAS 64472-06-6
Benzyl (2R)-pyrrolidine-2-carboxylate
CAS 64472-06-6C12H15NO2
Benzyl L-prolinate chemical structure, C12H15NO2, CAS 41324-66-7
Benzyl L-prolinate
CAS 41324-66-7C12H15NO2
t-Butyloxycarbonyl-asparaginylproline benzyl ester chemical structure, C21H29N3O6, CAS 35930-84-8
t-Butyloxycarbonyl-asparaginylproline benzyl ester
CAS 35930-84-8C21H29N3O6
Benzyl L-prolinate hydrochloride chemical structure, C12H16ClNO2, CAS 16652-71-4
Benzyl L-prolinate hydrochloride
CAS 16652-71-4C12H16ClNO2
Benzyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate chemical structure, C12H15NO3, CAS 68172-39-4
Benzyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate
CAS 68172-39-4C12H15NO3
Benzyl (4R)-1-Boc-4-hydroxy-D-prolinate chemical structure, C17H23NO5, CAS 132622-92-5
Benzyl (4R)-1-Boc-4-hydroxy-D-prolinate
CAS 132622-92-5C17H23NO5
2-Benzyl 1-tert-butyl (2S,3R)-3-hydroxypyrrolidine-1,2-dicarboxylate chemical structure, C17H23NO5, CAS 186132-82-1
2-Benzyl 1-tert-butyl (2S,3R)-3-hydroxypyrrolidine-1,2-dicarboxylate
CAS 186132-82-1C17H23NO5
(2S)-2-Benzyl 1-tert-butyl 5-methoxypyrrolidine-1,2-dicarboxylate chemical structure, C18H25NO5, CAS 331949-31-6
(2S)-2-Benzyl 1-tert-butyl 5-methoxypyrrolidine-1,2-dicarboxylate
CAS 331949-31-6C18H25NO5
(S)-2-Benzyl 1-tert-butyl pyrrolidine-1,2-dicarboxylate chemical structure, C17H23NO4, CAS 37787-77-2
(S)-2-Benzyl 1-tert-butyl pyrrolidine-1,2-dicarboxylate
CAS 37787-77-2C17H23NO4
(2S, 4S)-1-N-Boc-4-bromo-proline benzyl ester chemical structure, C17H22BrNO4, CAS 874162-95-5
(2S, 4S)-1-N-Boc-4-bromo-proline benzyl ester
CAS 874162-95-5C17H22BrNO4
O2-benzyl O1-tert-butyl (2S,4S)-4-(trifluoromethyl)pyrrolidine-1,2-dicarboxylate chemical structure, C18H22F3NO4, CAS 527704-55-8
O2-benzyl O1-tert-butyl (2S,4S)-4-(trifluoromethyl)pyrrolidine-1,2-dicarboxylate
CAS 527704-55-8C18H22F3NO4
Boc-hyp-obzl chemical structure, C17H23NO5, CAS 89813-47-8
Boc-hyp-obzl
CAS 89813-47-8C17H23NO5
N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-L-proline phenylmethyl ester chemical structure, C20H28N2O5, CAS 35084-69-6
N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-L-proline phenylmethyl ester
CAS 35084-69-6C20H28N2O5
N-Boc-glycyl-L-proline benzyl ester chemical structure, C19H26N2O5, CAS 29776-78-1
N-Boc-glycyl-L-proline benzyl ester
CAS 29776-78-1C19H26N2O5
Benzyl (2-Methoxy-2-oxoethyl)-L-prolinate chemical structure, C15H19NO4, CAS 87297-08-3
Benzyl (2-Methoxy-2-oxoethyl)-L-prolinate
CAS 87297-08-3C15H19NO4
Boc-L-4-trans-hydroxyproline benzyl ester chemical structure, C17H23NO5
Boc-L-4-trans-hydroxyproline benzyl ester
C17H23NO5
Benzyl (4S)-1-Boc-4-hydroxy-L-prolinate chemical structure, C17H23NO5, CAS 132622-90-3
Benzyl (4S)-1-Boc-4-hydroxy-L-prolinate
CAS 132622-90-3C17H23NO5
Boc-D-Pro-OBzl chemical structure, C17H23NO4, CAS 98265-60-2
Boc-D-Pro-OBzl
CAS 98265-60-2C17H23NO4
2-Benzyl 1-tert-butyl pyrrolidine-1,2-dicarboxylate chemical structure, C17H23NO4, CAS 2089093-10-5
2-Benzyl 1-tert-butyl pyrrolidine-1,2-dicarboxylate
CAS 2089093-10-5C17H23NO4
Benzyl 1-[(2R)-2-hydroxy-4-methylpentanoyl]-L-prolinate chemical structure, C18H25NO4, CAS 187753-73-7
Benzyl 1-[(2R)-2-hydroxy-4-methylpentanoyl]-L-prolinate
CAS 187753-73-7C18H25NO4
Boc-Val-Pro-OBzl chemical structure, C22H32N2O5, CAS 58872-03-0
Boc-Val-Pro-OBzl
CAS 58872-03-0C22H32N2O5
Benzyl L-valyl-L-prolinate chemical structure, C17H24N2O3, CAS 106665-76-3
Benzyl L-valyl-L-prolinate
CAS 106665-76-3C17H24N2O3