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Murcko scaffold

Ring system with 3 rings and 15 atoms

46 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
46
With full pages
6
Scaffold SMILES

c1ccc(-c2ccc3cnoc3n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccc3cnoc3n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 46 of 46 chemicals

6-(4-Chlorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylic acid chemical structure, C14H9ClN2O3, CAS 753468-45-0
6-(4-Chlorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylic acid
CAS 753468-45-0C14H9ClN2O3
3-Methyl-6-phenyl-4-(trifluoromethyl)isoxazolo(5,4-B)pyridine chemical structure, C14H9F3N2O, CAS 380419-66-9
3-Methyl-6-phenyl-4-(trifluoromethyl)isoxazolo(5,4-B)pyridine
CAS 380419-66-9C14H9F3N2O
Methyl 6-(4-chlorophenyl)-3-(propan-2-yl)[1,2]oxazolo[5,4-b]pyridine-4-carboxylate chemical structure, C17H15ClN2O3, CAS 796077-98-0
Methyl 6-(4-chlorophenyl)-3-(propan-2-yl)[1,2]oxazolo[5,4-b]pyridine-4-carboxylate
CAS 796077-98-0C17H15ClN2O3
Methyl 6-(4-chlorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate chemical structure, C15H11ClN2O3, CAS 878124-87-9
Methyl 6-(4-chlorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate
CAS 878124-87-9C15H11ClN2O3
3-Methyl-6-phenyl-(1,2)oxazolo(5,4-b)pyridine-4-carboxylic acid chemical structure, C14H10N2O3, CAS 923884-15-5
3-Methyl-6-phenyl-(1,2)oxazolo(5,4-b)pyridine-4-carboxylic acid
CAS 923884-15-5C14H10N2O3
Methyl 6-(4-fluorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate chemical structure, C15H11FN2O3, CAS 875424-64-9
Methyl 6-(4-fluorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate
CAS 875424-64-9C15H11FN2O3
3-Methyl-6-[2-(trifluoromethyl)phenyl]-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid chemical structure, C15H9F3N2O3, CAS 924383-70-0
3-Methyl-6-[2-(trifluoromethyl)phenyl]-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid
CAS 924383-70-0C15H9F3N2O3
6-(4-Fluorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylic acid chemical structure, C14H9FN2O3, CAS 923909-95-9
6-(4-Fluorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylic acid
CAS 923909-95-9C14H9FN2O3
6-(2-Fluorophenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid chemical structure, C14H9FN2O3, CAS 924129-81-7
6-(2-Fluorophenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid
CAS 924129-81-7C14H9FN2O3
3-Methyl-6-(4-methylphenyl)-(1,2)oxazolo(5,4-b)pyridine-4-carboxylic acid chemical structure, C15H12N2O3, CAS 924106-25-2
3-Methyl-6-(4-methylphenyl)-(1,2)oxazolo(5,4-b)pyridine-4-carboxylic acid
CAS 924106-25-2C15H12N2O3
Methyl 6-(4-methoxyphenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate chemical structure, C16H14N2O4, CAS 924221-72-7
Methyl 6-(4-methoxyphenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate
CAS 924221-72-7C16H14N2O4
6-(4-Chlorophenyl)-3-(propan-2-yl)-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid chemical structure, C16H13ClN2O3, CAS 881443-07-8
6-(4-Chlorophenyl)-3-(propan-2-yl)-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid
CAS 881443-07-8C16H13ClN2O3
6-(4-Methoxyphenyl)-3-methyl-(1,2)oxazolo(5,4-b)pyridine-4-carboxylic acid chemical structure, C15H12N2O4, CAS 938001-71-9
6-(4-Methoxyphenyl)-3-methyl-(1,2)oxazolo(5,4-b)pyridine-4-carboxylic acid
CAS 938001-71-9C15H12N2O4
6-(4-Ethoxyphenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid chemical structure, C16H14N2O4, CAS 953901-57-0
6-(4-Ethoxyphenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid
CAS 953901-57-0C16H14N2O4
6-(2,4-Dimethylphenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid chemical structure, C16H14N2O3, CAS 953731-77-6
6-(2,4-Dimethylphenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid
CAS 953731-77-6C16H14N2O3
6-(2,5-Difluorophenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid chemical structure, C14H8F2N2O3, CAS 953908-56-0
6-(2,5-Difluorophenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid
CAS 953908-56-0C14H8F2N2O3
6-(2-Methoxyphenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid chemical structure, C15H12N2O4, CAS 954253-94-2
6-(2-Methoxyphenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid
CAS 954253-94-2C15H12N2O4
6-(2-Chlorophenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid chemical structure, C14H9ClN2O3, CAS 954263-02-6
6-(2-Chlorophenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid
CAS 954263-02-6C14H9ClN2O3
6-(3-Chlorophenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid chemical structure, C14H9ClN2O3, CAS 954584-74-8
6-(3-Chlorophenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid
CAS 954584-74-8C14H9ClN2O3
6-(4-Fluorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carbohydrazide chemical structure, C14H11FN4O2, CAS 938005-34-6
6-(4-Fluorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carbohydrazide
CAS 938005-34-6C14H11FN4O2
6-(4-Chlorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carbohydrazide chemical structure, C14H11ClN4O2, CAS 938018-05-4
6-(4-Chlorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carbohydrazide
CAS 938018-05-4C14H11ClN4O2
3-Methyl-6-(4-nitrophenyl)isoxazolo[5,4-b]pyridine-4-carboxylic acid chemical structure, C14H9N3O5, CAS 938018-07-6
3-Methyl-6-(4-nitrophenyl)isoxazolo[5,4-b]pyridine-4-carboxylic acid
CAS 938018-07-6C14H9N3O5
4-Chloro-3-methyl-6-phenylisoxazolo[5,4-b]pyridine chemical structure, C13H9ClN2O, CAS 61658-64-8
4-Chloro-3-methyl-6-phenylisoxazolo[5,4-b]pyridine
CAS 61658-64-8C13H9ClN2O
N-Butyl-3-methyl-6-phenylisoxazolo[5,4-b]pyridin-4-amine chemical structure, C17H19N3O, CAS 61658-65-9
N-Butyl-3-methyl-6-phenylisoxazolo[5,4-b]pyridin-4-amine
CAS 61658-65-9C17H19N3O