CompoundList
Sign in
Murcko scaffold

4-(4-(Pyridin-2-yl)piperazin-1-yl)thieno[2,3-d]pyrimidine scaffold

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
6
With full pages
1
Scaffold SMILES

c1ccc(N2CCN(c3ncnc4sccc34)CC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(4-(Pyridin-2-yl)piperazin-1-yl)thieno[2,3-d]pyrimidine page
Murcko scaffold c1ccc(N2CCN(c3ncnc4sccc34)CC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

6-Ethyl-4-(4-(pyridin-2-yl)piperazin-1-yl)thieno[2,3-d]pyrimidine chemical structure, C17H19N5S, CAS 313649-28-4
6-Ethyl-4-(4-(pyridin-2-yl)piperazin-1-yl)thieno[2,3-d]pyrimidine
CAS 313649-28-4C17H19N5S
5,6-Dimethyl-4-(4-(pyridin-2-yl)piperazin-1-yl)thieno[2,3-d]pyrimidine chemical structure, C17H19N5S, CAS 379243-82-0
5,6-Dimethyl-4-(4-(pyridin-2-yl)piperazin-1-yl)thieno[2,3-d]pyrimidine
CAS 379243-82-0C17H19N5S
4-(4-(Pyridin-2-yl)piperazin-1-yl)thieno[2,3-d]pyrimidine chemical structure, C15H15N5S, CAS 786715-29-5
4-(4-(Pyridin-2-yl)piperazin-1-yl)thieno[2,3-d]pyrimidine
CAS 786715-29-5C15H15N5S
Ethyl 5-methyl-4-(4-pyridin-2-ylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxylate chemical structure, C19H21N5O2S, CAS 423142-90-9
Ethyl 5-methyl-4-(4-pyridin-2-ylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxylate
CAS 423142-90-9C19H21N5O2S
6-Ethyl-4-(4-(pyridin-2-yl)piperazin-1-yl)thieno[2,3-d]pyrimidine hydrochloride chemical structure, C17H20ClN5S, CAS 1215624-16-0
6-Ethyl-4-(4-(pyridin-2-yl)piperazin-1-yl)thieno[2,3-d]pyrimidine hydrochloride
CAS 1215624-16-0C17H20ClN5S
2-{4-[2-(2-Aminoethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl}nicotinamide chemical structure, C20H25N7OS, CAS 1269384-13-5
2-{4-[2-(2-Aminoethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl}nicotinamide
CAS 1269384-13-5C20H25N7OS