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Murcko scaffold

Ring system with 3 rings and 19 atoms

28 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
28
With full pages
5
Scaffold SMILES

O=C(c1ccccc1)N1CCSC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)N1CCSC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

2-[(2-Phenyl-1,3-thiazolidin-3-yl)carbonyl]benzoic acid chemical structure, C17H15NO3S, CAS 84210-70-8
2-[(2-Phenyl-1,3-thiazolidin-3-yl)carbonyl]benzoic acid
CAS 84210-70-8C17H15NO3S
2-(2-(4-Chlorophenyl)thiazolidine-3-carbonyl)benzoic acid chemical structure, C17H14ClNO3S, CAS 310452-84-7
2-(2-(4-Chlorophenyl)thiazolidine-3-carbonyl)benzoic acid
CAS 310452-84-7C17H14ClNO3S
[2-(4-Chloro-phenyl)-thiazolidin-3-yl]-(4-nitro-phenyl)-methanone chemical structure, C16H13ClN2O3S, CAS 331986-16-4
[2-(4-Chloro-phenyl)-thiazolidin-3-yl]-(4-nitro-phenyl)-methanone
CAS 331986-16-4C16H13ClN2O3S
[2-(3,4-Dimethoxyphenyl)-1,3-thiazolidin-3-yl]-(4-nitrophenyl)methanone chemical structure, C18H18N2O5S, CAS 314045-50-6
[2-(3,4-Dimethoxyphenyl)-1,3-thiazolidin-3-yl]-(4-nitrophenyl)methanone
CAS 314045-50-6C18H18N2O5S
Methyl 2-(4-chlorophenyl)-3-(4-methoxybenzoyl)-1,3-thiazolane-4-carboxylate chemical structure, C19H18ClNO4S, CAS 477725-42-1
Methyl 2-(4-chlorophenyl)-3-(4-methoxybenzoyl)-1,3-thiazolane-4-carboxylate
CAS 477725-42-1C19H18ClNO4S
[2-(4-Methylphenyl)-1,3-thiazolidin-3-yl](4-nitrophenyl)methanone chemical structure, C17H16N2O3S, CAS 537677-87-5
[2-(4-Methylphenyl)-1,3-thiazolidin-3-yl](4-nitrophenyl)methanone
CAS 537677-87-5C17H16N2O3S
(3-Chlorophenyl)(2-(4-fluorophenyl)thiazolidin-3-yl)methanone chemical structure, C16H13ClFNOS, CAS 854177-17-6
(3-Chlorophenyl)(2-(4-fluorophenyl)thiazolidin-3-yl)methanone
CAS 854177-17-6C16H13ClFNOS
2-(4-Chlorophenyl)-3-(4-methylbenzoyl)-1,3-thiazolane-4-carbohydrazide chemical structure, C18H18ClN3O2S, CAS 1008281-47-7
2-(4-Chlorophenyl)-3-(4-methylbenzoyl)-1,3-thiazolane-4-carbohydrazide
CAS 1008281-47-7C18H18ClN3O2S
Methyl 3-benzoyl-2-(4-chlorophenyl)-1,3-thiazolidine-4-carboxylate chemical structure, C18H16ClNO3S, CAS 477768-56-2
Methyl 3-benzoyl-2-(4-chlorophenyl)-1,3-thiazolidine-4-carboxylate
CAS 477768-56-2C18H16ClNO3S
Methyl 2-(4-chlorophenyl)-3-(4-methylbenzoyl)-1,3-thiazolane-4-carboxylate chemical structure, C19H18ClNO3S, CAS 477768-31-3
Methyl 2-(4-chlorophenyl)-3-(4-methylbenzoyl)-1,3-thiazolane-4-carboxylate
CAS 477768-31-3C19H18ClNO3S
(4-Nitrophenyl)(2-phenylthiazolidin-3-yl)methanone chemical structure, C16H14N2O3S, CAS 477515-74-5
(4-Nitrophenyl)(2-phenylthiazolidin-3-yl)methanone
CAS 477515-74-5C16H14N2O3S
[2-(2,3-Dimethoxyphenyl)-1,3-thiazolidin-3-yl](2-fluorophenyl)methanone chemical structure, C18H18FNO3S, CAS 6035-34-3
[2-(2,3-Dimethoxyphenyl)-1,3-thiazolidin-3-yl](2-fluorophenyl)methanone
CAS 6035-34-3C18H18FNO3S
2-(4-Fluorophenyl)-3-(2-methylbenzoyl)-N-(2-methylpropyl)-1,3-thiazolidine-4-carboxamide chemical structure, C22H25FN2O2S, CAS 5930-91-6
2-(4-Fluorophenyl)-3-(2-methylbenzoyl)-N-(2-methylpropyl)-1,3-thiazolidine-4-carboxamide
CAS 5930-91-6C22H25FN2O2S
(2-(4-(Dimethylamino)phenyl)thiazolidin-3-yl)(4-nitrophenyl)methanone chemical structure, C18H19N3O3S, CAS 312594-65-3
(2-(4-(Dimethylamino)phenyl)thiazolidin-3-yl)(4-nitrophenyl)methanone
CAS 312594-65-3C18H19N3O3S
2-[2-(3,4-Dimethoxyphenyl)-1,3-thiazolidine-3-carbonyl]benzoic acid chemical structure, C19H19NO5S, CAS 499986-54-8
2-[2-(3,4-Dimethoxyphenyl)-1,3-thiazolidine-3-carbonyl]benzoic acid
CAS 499986-54-8C19H19NO5S
(2-(4-Methoxyphenyl)thiazolidin-3-yl)(2-(trifluoromethyl)phenyl)methanone chemical structure, C18H16F3NO2S, CAS 2034262-19-4
(2-(4-Methoxyphenyl)thiazolidin-3-yl)(2-(trifluoromethyl)phenyl)methanone
CAS 2034262-19-4C18H16F3NO2S
3-(2-(4-(Trifluoromethyl)phenyl)thiazolidine-3-carbonyl)benzonitrile chemical structure, C18H13F3N2OS, CAS 2034286-88-7
3-(2-(4-(Trifluoromethyl)phenyl)thiazolidine-3-carbonyl)benzonitrile
CAS 2034286-88-7C18H13F3N2OS
4-(2-(3-Fluorophenyl)thiazolidine-3-carbonyl)benzonitrile chemical structure, C17H13FN2OS, CAS 2034614-27-0
4-(2-(3-Fluorophenyl)thiazolidine-3-carbonyl)benzonitrile
CAS 2034614-27-0C17H13FN2OS
Methyl 4-(2-(3-fluorophenyl)thiazolidine-3-carbonyl)benzoate chemical structure, C18H16FNO3S, CAS 2034243-09-7
Methyl 4-(2-(3-fluorophenyl)thiazolidine-3-carbonyl)benzoate
CAS 2034243-09-7C18H16FNO3S
(2-(3-Methoxyphenyl)thiazolidin-3-yl)(o-tolyl)methanone chemical structure, C18H19NO2S, CAS 2034614-40-7
(2-(3-Methoxyphenyl)thiazolidin-3-yl)(o-tolyl)methanone
CAS 2034614-40-7C18H19NO2S
(2-(3-Methoxyphenyl)thiazolidin-3-yl)(3-(trifluoromethyl)phenyl)methanone chemical structure, C18H16F3NO2S, CAS 2034614-46-3
(2-(3-Methoxyphenyl)thiazolidin-3-yl)(3-(trifluoromethyl)phenyl)methanone
CAS 2034614-46-3C18H16F3NO2S
(2-(3,4-Dichlorophenyl)thiazolidin-3-yl)(2-fluorophenyl)methanone chemical structure, C16H12Cl2FNOS, CAS 2034263-38-0
(2-(3,4-Dichlorophenyl)thiazolidin-3-yl)(2-fluorophenyl)methanone
CAS 2034263-38-0C16H12Cl2FNOS
3-(2-(3,4-Dichlorophenyl)thiazolidine-3-carbonyl)benzonitrile chemical structure, C17H12Cl2N2OS, CAS 2034263-45-9
3-(2-(3,4-Dichlorophenyl)thiazolidine-3-carbonyl)benzonitrile
CAS 2034263-45-9C17H12Cl2N2OS
Methyl 4-(2-(3,4-dichlorophenyl)thiazolidine-3-carbonyl)benzoate chemical structure, C18H15Cl2NO3S, CAS 2034287-94-8
Methyl 4-(2-(3,4-dichlorophenyl)thiazolidine-3-carbonyl)benzoate
CAS 2034287-94-8C18H15Cl2NO3S