Murcko scaffold
2-((4,5-Dihydro-1H-imidazol-2-yl)thio)-N-phenylacetamide scaffold
6 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 6
- With full pages
- 3
Scaffold SMILES
O=C(CSC1=NCCN1)Nc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
2-((4,5-Dihydro-1H-imidazol-2-yl)thio)-N-phenylacetamide
CAS 63236-62-4C11H13N3OS
2-(4,5-Dihydro-1H-imidazol-2-ylsulfanyl)-N-(4-methoxyphenyl)acetamide
CAS 403834-84-4C12H15N3O2S
N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-(4,5-dihydro-1H-imidazol-2-ylsulfanyl)acetamide
CAS 403835-84-7C12H11ClF3N3OS
RefChem:382796
CAS 63274-80-6C11H12N4O3S
2-((4,5-Dihydro-1H-imidazol-2-yl)thio)-N-(p-tolyl)acetamide hydrochloride
CAS 474648-40-3C12H16ClN3OS
2-(4,5-Dihydro-1H-imidazol-2-ylsulfanyl)-N-(4-methoxyphenyl)acetamide hydrochloride
CAS 474647-54-6C12H16ClN3O2S