Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 3 rings and 22 atoms

7 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 22
Chemicals: 7
With full pages: 3

Scaffold SMILES

O=C(c1ccc(C#Cc2ccccc2)cc1)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(c1ccc(C#Cc2ccccc2)cc1)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

(4-Hydroxypiperidin-1-yl)-[4-(2-phenylethynyl)phenyl]methanone chemical structure, C20H19NO2, CAS 393110-43-5

(4-Hydroxypiperidin-1-yl)-[4-(2-phenylethynyl)phenyl]methanone

CAS 393110-43-5C₂₀H₁₉NO₂

(3-(Hydroxymethyl)piperidin-1-yl)(4-((4-methoxyphenyl)ethynyl)phenyl)methanone chemical structure, C22H23NO3, CAS 1382451-87-7

(3-(Hydroxymethyl)piperidin-1-yl)(4-((4-methoxyphenyl)ethynyl)phenyl)methanone

CAS 1382451-87-7C₂₂H₂₃NO₃

Methanone, [(3S)-3-(hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]- chemical structure, C22H23NO3, CAS 1382481-80-2

Methanone, [(3S)-3-(hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-

CAS 1382481-80-2C₂₂H₂₃NO₃

Methanone, (4-hydroxy-4-methyl-1-piperidinyl)[4-[2-(4-methoxyphenyl)ethynyl]phenyl]- chemical structure, C22H23NO3, CAS 1382451-69-5

Methanone, (4-hydroxy-4-methyl-1-piperidinyl)[4-[2-(4-methoxyphenyl)ethynyl]phenyl]-

CAS 1382451-69-5C₂₂H₂₃NO₃

[(3R)-1-({4-[2-(4-Methoxyphenyl)ethynyl]phenyl}carbonyl)piperidin-3-yl]methanol chemical structure, C22H23NO3, CAS 1382481-79-9

[(3R)-1-({4-[2-(4-Methoxyphenyl)ethynyl]phenyl}carbonyl)piperidin-3-yl]methanol

CAS 1382481-79-9C₂₂H₂₃NO₃

[2-Fluoro-4-[2-(4-methoxyphenyl)ethynyl]phenyl]-[(3R)-3-hydroxypiperidin-1-yl]methanone chemical structure, C21H20FNO3, CAS 1443118-44-2

[2-Fluoro-4-[2-(4-methoxyphenyl)ethynyl]phenyl]-[(3R)-3-hydroxypiperidin-1-yl]methanone

CAS 1443118-44-2C₂₁H₂₀FNO₃

1-[4-(4-Methoxy-phenylethynyl)-benzoyl]-piperidine-3-carboxylic acid chemical structure, C22H21NO4, CAS 1382451-77-5

1-[4-(4-Methoxy-phenylethynyl)-benzoyl]-piperidine-3-carboxylic acid

CAS 1382451-77-5C₂₂H₂₁NO₄