CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 16 atoms

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
17
With full pages
3
Scaffold SMILES

O=C(NCCc1ccccc1)c1ccon1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCc1ccccc1)c1ccon1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

5-Methyl-N-[2-(4-sulfamoylphenyl)ethyl]-1,2-oxazole-3-carboxamide chemical structure, C13H15N3O4S, CAS 24477-36-9
5-Methyl-N-[2-(4-sulfamoylphenyl)ethyl]-1,2-oxazole-3-carboxamide
CAS 24477-36-9C13H15N3O4S
N-[2-(4-Chlorophenyl)ethyl]-5-methyl-1,2-oxazole-3-carboxamide chemical structure, C13H13ClN2O2, CAS 717858-94-1
N-[2-(4-Chlorophenyl)ethyl]-5-methyl-1,2-oxazole-3-carboxamide
CAS 717858-94-1C13H13ClN2O2
2-(4-Carbamoylsulfonylphenyl)ethyl-(5-methyl-1,2-oxazole-3-carbonyl)azanium chloride chemical structure, C14H16ClN3O5S
2-(4-Carbamoylsulfonylphenyl)ethyl-(5-methyl-1,2-oxazole-3-carbonyl)azanium chloride
C14H16ClN3O5S
N-[2-(Dimethylamino)-2-(4-methoxyphenyl)ethyl]-5-methyl-1,2-oxazole-3-carboxamide chemical structure, C16H21N3O3, CAS 877981-89-0
N-[2-(Dimethylamino)-2-(4-methoxyphenyl)ethyl]-5-methyl-1,2-oxazole-3-carboxamide
CAS 877981-89-0C16H21N3O3
[[4-[2-[[(5-Methyl-3-isoxazolyl)carbonyl]amino]ethyl]phenyl]sulfonyl]-carbamic Acid chemical structure, C15H17N3O6S, CAS 24489-02-9
[[4-[2-[[(5-Methyl-3-isoxazolyl)carbonyl]amino]ethyl]phenyl]sulfonyl]-carbamic Acid
CAS 24489-02-9C15H17N3O6S
(4-(Carbamoylsulphonyl)phenethyl)((5-methylisoxazol-3-yl)carbonyl)ammonium chloride chemical structure, C14H16ClN3O5S, CAS 80228-91-7
(4-(Carbamoylsulphonyl)phenethyl)((5-methylisoxazol-3-yl)carbonyl)ammonium chloride
CAS 80228-91-7C14H16ClN3O5S
N-(2-(2-Chlorophenyl)-2-(dimethylamino)ethyl)-5-methylisoxazole-3-carboxamide chemical structure, C15H18ClN3O2, CAS 1226440-65-8
N-(2-(2-Chlorophenyl)-2-(dimethylamino)ethyl)-5-methylisoxazole-3-carboxamide
CAS 1226440-65-8C15H18ClN3O2
5-Methyl-N-(3,3,3-trifluoro-2-hydroxy-2-phenylpropyl)isoxazole-3-carboxamide chemical structure, C14H13F3N2O3, CAS 1351586-80-5
5-Methyl-N-(3,3,3-trifluoro-2-hydroxy-2-phenylpropyl)isoxazole-3-carboxamide
CAS 1351586-80-5C14H13F3N2O3
N-(2-(4-(Dimethylamino)phenyl)-2-hydroxyethyl)-5-methylisoxazole-3-carboxamide chemical structure, C15H19N3O3, CAS 1421485-49-5
N-(2-(4-(Dimethylamino)phenyl)-2-hydroxyethyl)-5-methylisoxazole-3-carboxamide
CAS 1421485-49-5C15H19N3O3
N-(2-Methoxy-2-(o-tolyl)ethyl)-5-methylisoxazole-3-carboxamide chemical structure, C15H18N2O3, CAS 1797027-53-2
N-(2-Methoxy-2-(o-tolyl)ethyl)-5-methylisoxazole-3-carboxamide
CAS 1797027-53-2C15H18N2O3
N-(2-(2-Fluorophenyl)-2-methoxypropyl)-5-methylisoxazole-3-carboxamide chemical structure, C15H17FN2O3, CAS 1797160-13-4
N-(2-(2-Fluorophenyl)-2-methoxypropyl)-5-methylisoxazole-3-carboxamide
CAS 1797160-13-4C15H17FN2O3
N-(2-(3,4-Dimethoxyphenyl)-2-hydroxyethyl)-5-methylisoxazole-3-carboxamide chemical structure, C15H18N2O5, CAS 1797246-07-1
N-(2-(3,4-Dimethoxyphenyl)-2-hydroxyethyl)-5-methylisoxazole-3-carboxamide
CAS 1797246-07-1C15H18N2O5
N-(2-(3-Fluorophenyl)-2-methoxyethyl)-5-methylisoxazole-3-carboxamide chemical structure, C14H15FN2O3, CAS 1797023-95-0
N-(2-(3-Fluorophenyl)-2-methoxyethyl)-5-methylisoxazole-3-carboxamide
CAS 1797023-95-0C14H15FN2O3
N-(2-(2-Hydroxyethoxy)-2-(p-tolyl)ethyl)-5-methylisoxazole-3-carboxamide chemical structure, C16H20N2O4, CAS 1795485-14-1
N-(2-(2-Hydroxyethoxy)-2-(p-tolyl)ethyl)-5-methylisoxazole-3-carboxamide
CAS 1795485-14-1C16H20N2O4
N-(2-(2-Chlorophenyl)-2-methoxyethyl)-5-methylisoxazole-3-carboxamide chemical structure, C14H15ClN2O3, CAS 1788847-57-3
N-(2-(2-Chlorophenyl)-2-methoxyethyl)-5-methylisoxazole-3-carboxamide
CAS 1788847-57-3C14H15ClN2O3
N-(2-(3-Chlorophenyl)-2-methoxypropyl)-5-methylisoxazole-3-carboxamide chemical structure, C15H17ClN2O3, CAS 1788848-77-0
N-(2-(3-Chlorophenyl)-2-methoxypropyl)-5-methylisoxazole-3-carboxamide
CAS 1788848-77-0C15H17ClN2O3
N-[2-[4-(Aminosulfonyl)phenyl]ethyl]-4-chloro-5-methyl-3-isoxazolecarboxamide chemical structure, C13H14ClN3O4S, CAS 56914-85-3
N-[2-[4-(Aminosulfonyl)phenyl]ethyl]-4-chloro-5-methyl-3-isoxazolecarboxamide
CAS 56914-85-3C13H14ClN3O4S