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Murcko scaffold

2-(1H-Pyrazol-3-yl)pyrazine scaffold

323 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
323
With full pages
4
Scaffold SMILES

c1cnc(-c2ccn[nH]2)cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1H-Pyrazol-3-yl)pyrazine page
Murcko scaffold c1cnc(-c2ccn[nH]2)cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 323 chemicals

1-(1-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)-N-methylmethanamine chemical structure, C12H17N5, CAS 2098038-70-9
1-(1-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)-N-methylmethanamine
CAS 2098038-70-9C12H17N5
1-(1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)-N-methylmethanamine chemical structure, C11H14FN5, CAS 2098070-03-0
1-(1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)-N-methylmethanamine
CAS 2098070-03-0C11H14FN5
N-Methyl-1-(1-(prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methanamine chemical structure, C12H13N5, CAS 2098070-02-9
N-Methyl-1-(1-(prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methanamine
CAS 2098070-02-9C12H13N5
1-(1-(Difluoromethyl)-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)-N-methylmethanamine chemical structure, C10H11F2N5, CAS 2098131-01-0
1-(1-(Difluoromethyl)-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)-N-methylmethanamine
CAS 2098131-01-0C10H11F2N5
2-(4-(Bromomethyl)-1H-pyrazol-3-yl)pyrazine chemical structure, C8H7BrN4, CAS 2091213-35-1
2-(4-(Bromomethyl)-1H-pyrazol-3-yl)pyrazine
CAS 2091213-35-1C8H7BrN4
2-(4-Bromo-1,5-dimethyl-1H-pyrazol-3-yl)pyrazine chemical structure, C9H9BrN4, CAS 2092814-24-7
2-(4-Bromo-1,5-dimethyl-1H-pyrazol-3-yl)pyrazine
CAS 2092814-24-7C9H9BrN4
2-(4-Bromo-1-ethyl-5-methyl-1H-pyrazol-3-yl)pyrazine chemical structure, C10H11BrN4, CAS 2091576-87-1
2-(4-Bromo-1-ethyl-5-methyl-1H-pyrazol-3-yl)pyrazine
CAS 2091576-87-1C10H11BrN4
2-(4-Bromo-1-isopropyl-5-methyl-1H-pyrazol-3-yl)pyrazine chemical structure, C11H13BrN4, CAS 2091138-73-5
2-(4-Bromo-1-isopropyl-5-methyl-1H-pyrazol-3-yl)pyrazine
CAS 2091138-73-5C11H13BrN4
2-(4-Bromo-1-isobutyl-5-methyl-1H-pyrazol-3-yl)pyrazine chemical structure, C12H15BrN4, CAS 2098044-57-4
2-(4-Bromo-1-isobutyl-5-methyl-1H-pyrazol-3-yl)pyrazine
CAS 2098044-57-4C12H15BrN4
2-(4-Bromo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile chemical structure, C10H8BrN5, CAS 2092098-20-7
2-(4-Bromo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile
CAS 2092098-20-7C10H8BrN5
2-(4-Bromo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-amine chemical structure, C10H12BrN5, CAS 2091685-41-3
2-(4-Bromo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-amine
CAS 2091685-41-3C10H12BrN5
2-(4-Bromo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid chemical structure, C10H9BrN4O2, CAS 2098005-74-2
2-(4-Bromo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid
CAS 2098005-74-2C10H9BrN4O2
2-(4-Bromo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-ol chemical structure, C10H11BrN4O, CAS 2090852-66-5
2-(4-Bromo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-ol
CAS 2090852-66-5C10H11BrN4O
2-(4-Bromo-1-(2-chloroethyl)-5-methyl-1H-pyrazol-3-yl)pyrazine chemical structure, C10H10BrClN4, CAS 2090986-00-6
2-(4-Bromo-1-(2-chloroethyl)-5-methyl-1H-pyrazol-3-yl)pyrazine
CAS 2090986-00-6C10H10BrClN4
4-Bromo-1-methyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid chemical structure, C9H7BrN4O2, CAS 2092533-49-6
4-Bromo-1-methyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid
CAS 2092533-49-6C9H7BrN4O2
4-Bromo-1-ethyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid chemical structure, C10H9BrN4O2, CAS 2098074-35-0
4-Bromo-1-ethyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid
CAS 2098074-35-0C10H9BrN4O2
Methyl 4-bromo-1-methyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylate chemical structure, C10H9BrN4O2, CAS 2098074-42-9
Methyl 4-bromo-1-methyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylate
CAS 2098074-42-9C10H9BrN4O2
2-(4-Iodo-1,5-dimethyl-1H-pyrazol-3-yl)pyrazine chemical structure, C9H9IN4, CAS 2091213-86-2
2-(4-Iodo-1,5-dimethyl-1H-pyrazol-3-yl)pyrazine
CAS 2091213-86-2C9H9IN4
2-(1-Ethyl-4-iodo-5-methyl-1H-pyrazol-3-yl)pyrazine chemical structure, C10H11IN4, CAS 2090318-30-0
2-(1-Ethyl-4-iodo-5-methyl-1H-pyrazol-3-yl)pyrazine
CAS 2090318-30-0C10H11IN4
2-(4-Iodo-1-isopropyl-5-methyl-1H-pyrazol-3-yl)pyrazine chemical structure, C11H13IN4, CAS 2092641-15-9
2-(4-Iodo-1-isopropyl-5-methyl-1H-pyrazol-3-yl)pyrazine
CAS 2092641-15-9C11H13IN4
2-(4-Iodo-1-isobutyl-5-methyl-1H-pyrazol-3-yl)pyrazine chemical structure, C12H15IN4, CAS 2098108-39-3
2-(4-Iodo-1-isobutyl-5-methyl-1H-pyrazol-3-yl)pyrazine
CAS 2098108-39-3C12H15IN4
2-(4-Iodo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile chemical structure, C10H8IN5, CAS 2090610-04-9
2-(4-Iodo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile
CAS 2090610-04-9C10H8IN5
2-(4-Iodo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-amine chemical structure, C10H12IN5, CAS 2090987-97-4
2-(4-Iodo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-amine
CAS 2090987-97-4C10H12IN5
2-(4-Iodo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid chemical structure, C10H9IN4O2, CAS 2098074-93-0
2-(4-Iodo-5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid
CAS 2098074-93-0C10H9IN4O2